TXLNA (taxilin alpha)

2007-02-01  

Identity

HGNC
TXLNA
LOCATION
1p35.2
LOCUSID
200081
ALIAS
IL14,TXLN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 200081
MIM: 608676
HGNC: 30685
Ensembl: ENSG00000084652

Variants:

dbSNP: 200081
ClinVar: 200081
TCGA: ENSG00000084652
COSMIC: TXLNA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000084652ENST00000373609P40222
ENSG00000084652ENST00000373610P40222

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
170157572006Development of autoimmunity in IL-14alpha-transgenic mice.25
190385812009IL-14 alpha, the nexus for primary Sjögren's disease in mice and humans.21
151840722004Identification and characterization of taxilin isoforms.17
238167042013Identification of α-taxilin as an essential factor for the life cycle of hepatitis B virus.14
215519452011Increased alpha-taxilin protein expression is associated with the metastatic and invasive potential of renal cell cancer.8
265277382016Characterization of α-taxilin as a novel factor controlling the release of hepatitis C virus.7
210427092010Expression of α-taxilin in hepatocellular carcinoma correlates with growth activity and malignant potential of the tumor.6
246909212014α-Taxilin interacts with sorting nexin 4 and participates in the recycling pathway of transferrin receptor.2
186454992008Regulation of human interleukin 14 transcription in vitro and in vivo after renal transplantation.1
227851562012Interaction of α-taxilin localized on intracellular components with the microtubule cytoskeleton.1

Citation

Dessen P

TXLNA (taxilin alpha)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46367/txlna