UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X)

2017-08-01  

Identity

HGNC
LOCATION
22q12.2
LOCUSID
ALIAS
HSPC051,HSPC119,HSPC151,QCR9,UCCR7.2,UCRC
FUSION GENES

Other Information

Locus ID:

NCBI: 29796
MIM: 610843
HGNC: 30863
Ensembl: ENSG00000184076

Variants:

dbSNP: 29796
ClinVar: 29796
TCGA: ENSG00000184076
COSMIC: UQCR10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184076ENST00000330029Q9UDW1
ENSG00000184076ENST00000401406Q9UDW1

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Alzheimer's diseaseKEGGko05010
Huntington's diseaseKEGGko05016
Oxidative phosphorylationKEGGhsa00190
Alzheimer's diseaseKEGGhsa05010
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
Cardiac muscle contractionKEGGhsa04260
Cardiac muscle contractionKEGGko04260
Metabolic pathwaysKEGGhsa01100
Cytochrome bc1 complexKEGGhsa_M00152
Cytochrome bc1 complexKEGGM00152
Non-alcoholic fatty liver disease (NAFLD)KEGGhsa04932
Non-alcoholic fatty liver disease (NAFLD)KEGGko04932
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Respiratory electron transportREACTOMER-HSA-611105

References

Pubmed IDYearTitleCitations
160540892005Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing.446
222779672012Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.141
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
274011492016Novel fusion genes and chimeric transcripts in ependymal tumors.2

Citation

Dessen P

UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56988/uqcr10