VGLL2 (vestigial like family member 2)

2016-05-01  

Identity

HGNC
VGLL2
LOCATION
6q22.1
LOCUSID
245806
ALIAS
VGL2,VITO1

Other Information

Locus ID:

NCBI: 245806
MIM: 609979
HGNC: 20232
Ensembl: ENSG00000170162

Variants:

dbSNP: 245806
ClinVar: 245806
TCGA: ENSG00000170162
COSMIC: VGLL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170162ENST00000326274Q8N8G2
ENSG00000170162ENST00000352536Q8N8G2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
123765442002Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.48
265012262016A Molecular Study of Pediatric Spindle and Sclerosing Rhabdomyosarcoma: Identification of Novel and Recurrent VGLL2-related Fusions in Infantile Cases.30
147622062004VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation.21

Citation

Dessen P

VGLL2 (vestigial like family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55796/vgll2