VPS37B (VPS37B subunit of ESCRT-I)

2014-11-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 79720
MIM: 610037
HGNC: 25754
Ensembl: ENSG00000139722

Variants:

dbSNP: 79720
ClinVar: 79720
TCGA: ENSG00000139722
COSMIC: VPS37B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139722ENST00000267202Q9H9H4
ENSG00000139722ENST00000267202A0A024RBU0
ENSG00000139722ENST00000371248F5H1F6
ENSG00000139722ENST00000535765F5H4M0

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
ESCRT-I complexKEGGhsa_M00409
ESCRT-I complexKEGGM00409
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Assembly Of The HIV VirionREACTOMER-HSA-175474
Synthesis And Processing Of GAG, GAGPOL PolyproteinsREACTOMER-HSA-174495
Membrane binding and targetting of GAG proteinsREACTOMER-HSA-174490
Budding and maturation of HIV virionREACTOMER-HSA-162588
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Endosomal Sorting Complex Required For Transport (ESCRT)REACTOMER-HSA-917729

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
239247352013VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-I.7

Citation

Dessen P

VPS37B (VPS37B subunit of ESCRT-I)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75634/vps37b