YTHDF1 (YTH N6-methyladenosine RNA binding protein 1)

2018-11-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
C20orf21,DF1
FUSION GENES

Other Information

Locus ID:

NCBI: 54915
MIM: 616529
HGNC: 15867
Ensembl: ENSG00000149658

Variants:

dbSNP: 54915
ClinVar: 54915
TCGA: ENSG00000149658
COSMIC: YTHDF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149658ENST00000370334Q5JXC6
ENSG00000149658ENST00000370339Q9BYJ9

Expression (GTEx)

0
10
20
30
40
50
60
70

References

Pubmed IDYearTitleCitations
273718282016N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.76
263184512015Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.47
307285042019Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.43
294393112018Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma.39
316538492019YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.14

Citation

Dessen P

YTHDF1 (YTH N6-methyladenosine RNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57717/ythdf1