| Clinics and Pathology |
| Disease | myeloid malignancies |
| Epidemiology | only 2 cases to date |
| Clinics | a 1 yr old infant with M5a acute non lymphocytic leukemia (ANLL), and a 21 yr old female patient with refractory anemia with ringed sideroblasts (RARS) and a suspicion of Fanconi anemia11 yrs before diagnosis of RARS |
| Prognosis | death occurred 8 mths after diagnosis in the case with ANLL |
| Cytogenetics |
| Cytogenetics Morphological | the translocation presents as + der(1) t(1;19)(p13;p13) in both known cases |
| Additional anomalies | sole anomaly in one of the two cases |
| Genes involved and Proteins |
| Note | genes involved are unknown |
| External links |
| Other database | t(1;19)(p13;p13.1) | Mitelman database (CGAP - NCBI) | |
| Other database | t(1;19)(p13;p13.1) | CancerChromosomes (NCBI) |
| To be noted |
| Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
| Bibliography |
| Novel der(1)t(1;19) in two patients with myeloid neoplasias. |
| Tchinda J, Volpert S, Neumann T, Kennerknecht I, Ritter J, Bˆºchner T, Berdel WE, Horst J |
| Cancer genetics and cytogenetics. 2002 ; 133 (1) : 61-65. |
| PMID 11890991 |
| Contributor(s) |
| Written | 04-2002 | Jean-Loup Huret |
| Citation |
| This paper should be referenced as such : |
| Huret JL . t(1;19)(p13;p13.1). Atlas Genet Cytogenet Oncol Haematol. April 2002 . URL : http://AtlasGeneticsOncology.org/Genes/t0119p13p13ID1230.html |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sat Dec 6 18:02:12 2008 |
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