Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Chromosome 2

Chromosome 2 : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret

Leukaemia     

t(1;2)(q25;p23)
t(1;2)(q12;q37)
inv(2)(p23q35)
Trisomy 2
t(2;3)(p23;q21)
t(2;3)(p15-23;q26-27)
t(2;3)(p12;q27)
t(2;4)(p22;q12)
t(2;4)(p23;q25-q35)
t(2;5)(p23;q35)
t(2;8)(p12;q24)
t(2;9)(p11;p13)
t(2;11)(p21;q23)
t(2;11)(q11;q23)
t(2;11)(q31;p15) (MDS, AML; NUP98 and HOXD13; rare)
t(2;11)(q31;p15) (MDS, AML; NUP98 and HOXD11; rare)
t(2;11)(q37;q23) (AML; SEPT2 and MLL; rare)
t(2;11)(q37;q23) in AML
t(2;12)(q31;p13)
t(2;13)(p16;q12)
t(2;14)(p13;q32)
t(2;17)(p23;q23)
t(2;17)(p23;q25)
t(2;18)(p11;q21)
t(2;19)(p11;p13)
t(2;19)(p12;q13) IGK/BCL3
t(2;21)(p11;q22)
t(2;22)(p13;q11) (NHL; REL and IgL; rare)
t(2;22)(p23;q11.2)
t(2;22)(p23;q11.2)
t(X;2)(q11;p23)

Solid Tumors     

t(1;2)(q25;p23)
t(1;2)(q25;p23)
t(1;2)(q25;p23)
inv(2)(p21p23)
t(2;2)(p23;q13)
t(2;2)(p23;q13)
t(2;11)(p23;p15)
t(2;11)(p23;p15)
t(2;13)(q35;q14)
t(2;13)(q35;q14)
t(2;17)(p23;q23)
t(2;17)(p23;q23)
t(2;19)(p23;p13)
t(2;19)(p23;p13.1)
t(2;19)(p23;p13.1)
t(2;22)(q23;q12)

Cancer prone diseases     

Carney complex (CNC)
Familial clear cell renal cancer
Hereditary non polyposis colorectal carcinoma (HNPCC Syndrome)
Hereditary Pancreatic Cancer
Trichothiodystrophy (TTD)
Waardenburg syndrome (WS)
Xeroderma pigmentosum

All Genes by Location (Kb)
Chromosome 2 by location

Losses / Amplicons     

BONE/SOFT TISSUE

External links     

  • Chromosome 2 - HUGO Chromosomes
  • Chromosome 2 - GoldenPath - Santa Cruz
  • Chromosome 2 - Ensembl Project
  • Chromosome 2 - Map View - NCBI
  • Chromosome 2 - GDB (Genome Data Base)
  • Chromosome 2 - OMIM Gene map
  • Chromosome 2 - Genomic Variants
  • Chromosome 2 - HAPMAP Project
  • Chromosome 2 - Genome Channel - ORNL
  • Chromosome 2 - LaunchPad HGMIS
  • Chromosome 2 - Human Protein Atlas
  • Chromosome 2 - SpliceNest
  • Human BAC Resource (NCBI)
  • FISH-mapped BACs (CCAP)
  • Genetic Maps (CHLC)
  • YACs mapped by FISH (Bari)
  • PCP (Partial Chromosome Paints) (Bari)
  • Positional Cloning Project (Berlin Dahlem)
  • Mouse homology - OMIM - NCBI
  • Cancer GeneWeb
  • GeneCards (Weizmann)
  • IMGT, the international ImMunoGeneTics database (Montpellier,France)
  • Human Proteomics Initiative (Expasy)

    • Genes

    Annotated genes
    Ordered by Name Ordered by Location
     Kb pter-qter
    ACVR2A 148319.040 2q22.2-q23.3
    ADAM23 207016.613 2q33
    AFF3 99530.148 2q11.2-q12
    ALK 29269.144 2p23
    ATF2 175647.252 2q32
    ATIC 215884.937 2q35
    BARD1 215301.520 2q34-q35
    BCL11A 60531.806 2p16.1
    BIN1 127522.078 2q14
    BIRC6 32435.600 2p22.3
    BOK 242146.865 2q37.3
    CFLAR 201691.632 2q33-q34
    CXCR7 237143.119 2q37.3
    DIRC1 189306.710 2q33
    DIRC3 217856.992 2q35
    E2F6 11501.952 2p25.1
    ERCC3 127731.336 2q21
    HSPD1 198059.553 2q33.1
    IGK@ 88937.794 2p12
    IKZF2 213572.656 2q13.1
    IL1B 113303.808 2q14
    LHCGR 48767.417 2p21
    MAP4K4 101680.920 2q11.2-q12
    MIRN10B 176723.277 2
    MSH2 47483.767 2p21
    MSH6 47863.725 2p16
    MYCN 15998.134 2p24.3
    NLRC4 32303.022 2p22-p21
    PAX3 222866.593 2q36.1
    PMS1 190357.056 2q31-q33|2q31.1
    RANBP2 108702.369 2q13
    REL 60962.256 2p13-p12
    RHOB 20510.316 2p24
    RTN4 55052.831 2p14-p13
    SDC1 20264.039 2p24.1
    SEPT2 241903.396 2q37.3
    STRN 36928.976 2p22.2
    TACSTD1 47449.971 2p21
    Other genes
    possibly implicated
    in cancer
    Ordered by Name Ordered by Location
     Kb pter-qter
    AAK1 69538.631 2p24.3-p14
    AAMP 218837.096 2q
    ABCA12 215504.511 2q34
    ABCB11 169487.695 2q24
    ABCB6 219782.738 2q36
    ABI2 203901.248 2
    ACP1 254.872 2p25
    ACSL3 223433.976 2q34-q35
    ACTR1B 97638.863 2q11.1-q11.2
    ACTR2 65308.406 2p14
    ACTR3 114364.007 2q14.1
    ACVR1 158301.205 2q23-q24
    ACVR1C 158091.525 2q24.2
    ACYP2 54195.914 2p16.2
    ADAM17 9546.862 2p25
    ADI1 3480.697 2p25.2
    ADRA2B 96142.350 2p13-q13
    AHSA2 61258.325 2p14
    ALPI 233029.077 2q37.1
    ALPPL2 232979.796 2q37
    ALS2 202273.522 2q33-q35
    ALS2CR2 202024.637 2q33.1
    ANAPC1 112243.111 2q12.1
    ANKRD36B 97487.693 2q11.2
    ANKRD44 197567.495 2q33.1
    ANO7 241776.597 2q37.3
    ANTXR1 69093.993 2p13.1
    ANXA4 69822.631 2p13.3
    APLF 68548.246 2
    APOB 21077.806 2p24-p23
    ARHGAP15 143603.369 2q22.2-q22.3
    ARHGAP25 68815.472 2p13.3
    ARHGEF4 131390.694 2q22
    ARMC9 231771.586 2q37.1
    ARPC2 218790.365 2q36.1
    ASPRV1 70040.728 2p13.3
    ATG4B 242225.700 2q37.3
    B3GNT2 62276.766 2p15
    BAZ2B 159883.736 2q24.2
    BCL2L11 111594.962 2q13
    BCS1L 219232.623 2q35
    BMP10 68946.117 2p13.2
    BMPR2 202949.295 2q33-q34
    BRE 27967.061 2p23
    BUB1 111111.881 2p11-q21
    C1D 68122.840 2p13-p12
    C2orf12 160836.908 2q24.3
    C2orf13 68548.246 2
    C2orf25 150134.397 2q23
    C2orf29 101235.777 2q12.1
    C2orf40 106048.545 2q12.2
    CAB39 231285.909 2q37.1
    CAD 27293.762 2p22-p21
    CAPG 85475.382 2p11.2
    CAPN10 241174.818 2q37.3
    CASP10 201755.866 2q33-q34
    CASP8 201806.411 2q33-q34
    CCDC88A 55368.482 2p16.3
    CCL20 228386.802 2q33-q37
    CCNT2 135392.863 2q21.3
    CD28 204279.443 2q33
    CD302 160333.610 2q24.2
    CD8A 86865.239 2p12
    CD8B 86922.200 2p12
    CDC42EP3 37724.247 2p21
    CDCA7 173927.807 2q31.1
    CDK5R2 219532.642 2q35
    CDKL4 39259.192 2p22.3
    CENPA 26862.387 2p24-p21
    CHN1 175372.338 2q31-q32.1
    CIAO1 96295.611 2q11.1-q11.2
    CIB4 26657.577 2p23.3
    CLK1 201425.978 2q33
    CNTNAP5 124499.334 2q14.1
    COL3A1 189547.344 2q32.2
    COL4A3 227737.525 2q36-q37
    COL6A3 237897.394 2q37
    COPS7B 232359.406 2q37.1
    COX5B 97628.953 2cen-q13
    COX7A2L 42431.148 2p21
    CPS1 211050.654 2p
    CREB1 208102.931 2q34
    CRIM1 36436.901 2p21
    CTLA4 204440.754 2q33
    CUL3 225043.113 2q36.2
    CXCR4 136588.389 2q21
    CYP1B1 38148.250 2p22.2
    DBI 119840.974 2q12-q21
    DDX1 15649.221 2p24
    DDX18 118288.725 2q21.2
    DFNB59 179026.351 2q31.2
    DHX57 38878.379 2p22.3
    DNAJB2 219852.284 2q32-q34
    DNAJC10 183289.244 2q32.1
    DNAJC5G 27351.793 2p23
    DNMT3A 25309.349 2p23
    DOK1 74635.368 2p13
    DPP4 162557.001 2q24.3
    DPYSL5 26924.473 2p23.3
    DTYMK 242263.830 2q37.3
    DUSP2 96172.635 2q11
    DYSF 71534.261 2p13.3
    EEF1B2 206732.563 2q33.3
    EFEMP1 55946.606 2p16
    EIF2AK2 37187.203 2p22-p21
    EIF2AK3 88637.374 2p12
    EML4 42250.020 2p21
    EN1 119316.217 2q14.2
    EPAS1 46378.067 2p21-p16
    EPC2 149119.030 2q23
    EPHA4 221990.991 2q36.3
    ERBB4 211948.687 2q33.3-q34
    ETAA1 67477.946 2p14
    FAM119A 208182.084 2q33.3
    FAM84A 14690.307 2p24.3
    FANCL 58239.882 2p16.1
    FAP 162735.446 2q23
    FEV 219554.053 2q36
    FHL2 105343.715 2q12.2
    FN1 215933.424 2q34
    FOSL2 28469.283 2p23.3
    FOXD4L1 113973.131 2q14.1
    FOXN2 48395.299 2p22-p16
    FRZB 183406.982 2qter
    FSHR 49043.156 2p21-p16
    FZD5 208335.555 2q33-q34
    FZD7 202607.555 2q33
    GAL3ST2 242364.913 2q37.2
    GALNT3 166312.559 2q24-q31
    GBX2 236739.046 2q37.2
    GCG 162707.634 2q36-q37
    GCKR 27573.210 2p23
    GDF7 20729.905 2p24.1
    GEMIN6 38858.831 2p22.1
    GEN1 17798.895 2p24.2
    GKN1 69055.209 2p13.3
    GKN2 69025.868 2p14
    GLI2 121271.337 2q14
    GLS 191453.792 2q32-q34
    GNLY 85774.925 2p12-q11
    GPBAR1 218833.983 2q35
    GPC1 241023.788 2q35-q37
    GPD2 157001.146 2q24.1
    GPN1 27705.407 2p23.3
    GPR39 132890.617 2q21-q22
    GRB14 165057.569 2q22-q24
    GREB1 11591.693 2p25.1
    HAT1 172487.204 2q31.2-q33.1
    HDAC4 239634.801 2q37.3
    HDLBP 241815.352 2q37.3
    HECW2 196772.222 2q32.3
    HES6 238811.647 2q37.3
    HJURP 234410.225 2q37.1
    HK2 74913.290 2p13
    HOXD11 176680.330 2q31.1
    HOXD13 176665.778 2q31.1
    HOXD3 176737.051 2q31.1
    HOXD9 176695.659 2q31.1
    HSPE1 198073.365 2q33.1
    HTRA2 74610.040 2p13.1
    ICOS 204509.748 2q33
    ID2 8739.564 2p25
    IDH1 208809.198 2q32-qter
    IFIH1 162831.835 2q24.2
    IGFBP2 217206.372 2q33-q34
    IGFBP5 217245.073 2q33-q36
    IHH 219627.390 2q33-q35
    IL18R1 102345.529 2q12
    IL1A 113247.963 2q14
    IL1F7 113387.019 2q12-q14.1
    IL1F9 113452.077 2q12-q21
    IL1R1 102136.834 2q12
    IL1R2 101974.738 2q12-q22
    IL1RL1 102320.149 2q12
    IL1RN 113591.941 2q14.2
    IL8RA 218735.813 2q35
    IL8RB 218698.991 2q35
    ING5 242290.129 2q37.3
    INHA 220145.198 2q33-q36
    INHBB 120820.189 2cen-q13
    INPP1 190916.441 2q32
    INPP4A 98427.845 2q11.2
    INPP5D 233633.280 2q37.1
    INSIG2 118562.520 2q14.1
    IRS1 227304.277 2q36
    ITGA4 182029.864 2q31.3
    ITGA6 173000.560 2q31.1
    ITGAV 187163.045 2q31-q32
    ITGB1BP1 9463.266 2p25.2
    ITGB6 160666.479 2q24.2
    ITSN2 24279.239 2pter-p25.1
    JMJD1A 86521.865 2p11.2
    KBTBD10 170074.458 2p14-q14.3
    KCMF1 85051.742 2p11.2
    KCNIP3 95376.495 2q21.1
    KCNJ3 155263.339 2q24.1
    KHK 27163.115 2p23.3-p23.2
    KIAA1486 225973.846 2q36.3
    KIDINS220 8786.511 2p24
    LANCL1 211004.220 2q33-q35
    LBH 30307.901 2p23.1
    LCT 136261.885 2q21
    LIMS1 108571.199 2q12.3
    LIMS2 128112.471 2q21.1
    LOXL3 74613.454 2p13
    LRP1B 140705.466 2q21.2
    LRP2 169691.865 2q24-q31
    LTBP1 33213.181 2p22-p21
    LY75 160368.114 2q24
    MAL 95055.206 2cen-q13
    MAP1D 172573.050 2q31.1
    MAP2 209997.016 2q34-q35
    MAP3K2 127778.609 2q21.1
    MAP4K3 39329.926 2p22.3
    MAPRE3 27047.029 2p23.3-p23.1
    MAT2A 85619.799 2p11.2
    MCM6 136313.666 2q14-q21
    MDH1 63669.626 2p23
    MEIS1 66516.036 2p14
    MERTK 112372.662 2q14.1
    MGAT4A 98602.001 2q12
    MGAT5 134728.300 2q21
    MOBKL1B 74236.719 2p13.1
    MSGN1 17861.267 2p24.2
    MSTN 190628.671 2q32.1
    MTA3 42649.175 2p22.1
    MXD1 69995.707 2p13-p12
    MYCNOS 15993.837 2p24.1
    MYL1 210863.113 2q33-q34
    MYO3B 170742.901 2q31.1-q31.2
    NAB1 191222.093 2q32.3-q33
    NAG 15224.483 2p24
    NCAPH 96365.211 2q11.2
    NCL 232027.703 2q12-qter
    NCOA1 24660.850 2p23
    NEB 152050.099 2q22
    NEUROD1 182249.439 2q32
    NFE2L2 177803.279 2q31
    NGEF 233451.640 2q37
    NHEJ1 219648.290 2q35
    NMI 151835.228 2q23
    NOSTRIN 169367.399 2q31.1
    NPAS2 100803.045 2q11.2
    NR4A2 156889.190 2q22-q23
    NRBP1 27504.977 2p23
    NRP2 206255.469 2q33.3
    ODC1 10497.959 2p25
    ORC2L 201483.139 2q33
    ORC4L 148408.202 2q22-q23
    OSR1 19414.727 2p24.1
    OXER1 42843.143 2p22.1
    PASK 241694.188 2q37.3
    PAX8 113690.045 2q13
    PCBP1 70168.205 2p13-p12
    PCGEM1 193322.815 2q32.3
    PCGF1 74585.678 2p13.1
    PDCD1 242440.706 2q37.3
    PDE11A 178196.223 2q31.3
    PDK1 173129.025 2q31.1
    PELI1 64173.290 2p13.3
    PER2 238817.418 2q37.3
    PFTK2 202379.443 2q33.2
    PIGF 46661.917 2p21-p16
    PIP5K3 208839.236 2q34
    PLCD4 219180.876 2q35
    PLCL1 198377.778 2q33
    PLEK 68445.826 2p13.3
    PLEKHA3 179053.445 2q31.2
    PNPT1 55714.702 2p15
    POLE4 75039.283 2p12
    POLR1B 113016.084 2q13
    POLR2D 128320.705 2q21
    POMC 25237.226 2p23
    PPM1B 44249.504 2p22.1
    PPM1G 27457.565 2p23.3
    PPP1CB 28828.130 2p23
    PPP1R1C 182558.796 2q31.3
    PPP1R7 241738.575 2q37.3
    PPP3R1 68259.493 2p16-p15
    PREPL 44399.406 2p22.1
    PRKAG3 219395.350 2
    PRKCE 45732.547 2p21
    PRKD3 37331.150 2p21
    PRLH 238139.956 2q37.3
    PROC 127892.487 2q13-q14
    PROM2 95303.928 2q11.1
    PSD4 113648.031 2q13
    PSME4 53944.708 2p16.1
    PTMA 232281.479 2q37.1
    PTMAP7 232281.660 14q32
    PTPN18 130830.088 2q21
    PTPN4 120233.677 2q14.2
    PTPRN 219862.589 2q35-q36.1
    PUM2 20311.934 2p22-p21
    PXDN 1614.666 2p25.3
    RAB10 26110.478 2p23.3
    RAB11FIP5 73154.018 2p13
    RAB17 238147.704 2q37.3
    RAB1A 65167.493 2p14
    RAB6C 130453.705 2q21.1
    RABL2A 114101.287 2q13
    RALB 120726.884 2cen-q13
    RAPH1 204014.437 2q33
    RASGRP3 33514.920 2p25.1-p24.1
    RBJ 25020.009 2p23.3
    RBMS1 160838.759 2q24.2
    REG1A 79201.092 2p12
    REG3A 79237.641 2p12
    REV1 99383.370 2q11.1-q11.2
    RHOQ 46623.371 2p21
    RND3 151032.955 2q23.3
    RNF103 86684.027 2p11.2
    RNF144A 6974.974 2p25.2
    RNF149 101258.985 2q12.1
    RNF25 219236.831 2q35
    ROCK2 11239.229 2p24
    RPRM 154042.098 2q24.1
    RPS27A 55313.328 2p16
    RRM2 10180.186 2p25-p24
    RTKN 74506.496 2p13.1
    SAG 233881.048 2q37.1
    SATB2 199842.469 2q33.1
    SCG2 224169.902 2q35-q36
    SCLY 238634.371 2q37.3
    SCN1A 166553.916 2q24.3
    SCN9A 166759.943 2q24
    SCTR 119913.889 2q14.1
    SEMA4F 74734.901 2p13.1
    SEPT10 109657.665 2q13
    SERPINE2 224548.121 2q33-q35
    SESTD1 179674.664 2q31.3
    SIX3 45022.541 2p21
    SLC11A1 218954.996 2q35
    SLC19A3 228258.170 2q37
    SLC20A1 113119.998 2q11-q14
    SLC4A10 162189.091 2q23-q24
    SMARCAL1 216985.718 2q35
    SMC6 17708.562 2p24.3
    SMEK2 55629.018 2p16.1
    SMPD4 130625.450 2q21.1
    SMYD1 88148.497 2p11.1
    SMYD5 73294.874 2p12
    SOS1 39062.194 2p21
    SOX11 5750.250 2p25
    SP100 230989.115 2q37.1
    SP3 174481.504 2q31
    SP5 171280.107 2q31
    SPHKAP 228552.919 2q36.3
    SPRED2 65391.489 2p14
    SPTBN1 54536.958 2p21
    SRD5A2 31603.160 2p23.1
    SSB 170363.635 2q31.1
    SSFA2 182464.717 2q32.1
    STAT1 191542.007 2q32.2-q32.3
    STAT4 191602.551 2q32.2-q32.3
    STK11IP 220170.840 2q35
    STK16 219818.436 2q35
    STK17B 196710.103 2q33.1
    STK25 242083.105 2q37.3
    STK36 219245.053 2q35
    STK39 168518.776 2q24.3
    SUMO1 202779.148 2q33
    SUPT7L 27727.183 2p23.3
    TACR1 75129.738 2p13.1-p12
    TAF1B 9901.024 2p25
    TANK 161701.712 2q24-q31
    TCF7L1 85214.245 2p11.2
    TET3 74126.958 2p13.1
    TFPI 188051.551 2q32
    TGFA 70527.925 2p13
    TGFBRAP1 105249.972 2q12.1
    THADA 43311.479 2p21
    TIA1 70290.080 2p13
    TLK1 171556.814 2q31.1
    TLX2 74595.119 2p13.1
    TMEFF2 192522.992 2q32.3
    TMEM16G 241776.597 2q37.3
    TMSB10 84986.274 2p11.2
    TNFAIP6 151922.351 2q23.3
    TNP1 217432.427 2q35-q36
    TNS1 218372.757 2q35-q36
    TP53I3 24153.809 2p23.3