Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Chromosome 6

Chromosome 6 : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret

Leukaemia     

t(1;6)(p35;p25)
t(3;6)(q25;q26)
t(3;6)(q27;p21) (NHL; BCL6 and SFRS3; rare)
t(3;6)(q27;p21) (NHL; BCL6 and PIM1; rare)
t(3;6)(q27;q15) (NHL; BCL6 and SNHG5; rare)
del(6q) abnormalities in lymphoid malignancies
del(6q) in Multiple Myeloma
i(6)(p10)
+6 or trisomy 6
t(6;7)(q23;q34)
t(6;8)(q11;q11)
t(6;8)(q27;p12)
t(6;9)(p23;q34)
t(6;11)(q27;q23)
t(6;11)(q13;q23)
t(6;11)(q21;q23) (AML, T-NHL; AF6q21 and MLL; rare)
t(6;12)(p21;p13) in lymphoid malignancies
t(6;12)(q15;p13)/NHL (AML, T-CLD; - ; rare)
t(6;12)(q21-22;p13) (AML, B-ALL, T-ALL, CLD; FRK and ETV6 in AML; rare)
t(6;12)(q22-23;p13) (Cell line (B-ALL); STL and ETV6; rare)
t(6;14)(p21;q32)
t(6;14)(p22;q32)
t(6;14)(p25;q32) ( CLD; IRF4 and IgH; rare)
t(6;21)(p22;q22)
t(X;6)(p11;q23)

Solid Tumors     

inv(6)(p13;q25)
6p21 rearrangements
t(6;11)(p21;q12)

Cancer prone diseases     

All Genes by Location (Kb)
Chromosome 6 by location

Losses / Amplicons     

BONE/SOFT TISSUE

External links     

  • Chromosome 6 - HUGO Chromosomes
  • Chromosome 6 - GoldenPath - Santa Cruz
  • Chromosome 6 - Ensembl Project
  • Chromosome 6 - Map View - NCBI
  • Chromosome 6 - GDB (Genome Data Base)
  • Chromosome 6 - OMIM Gene map
  • Chromosome 6 - Genomic Variants
  • Chromosome 6 - HAPMAP Project
  • Chromosome 6 - Genome Channel - ORNL
  • Chromosome 6 - LaunchPad HGMIS
  • Chromosome 6 - Human Protein Atlas
  • Chromosome 6 - SpliceNest
  • Human BAC Resource (NCBI)
  • FISH-mapped BACs (CCAP)
  • Genetic Maps (CHLC)
  • YACs mapped by FISH (Bari)
  • PCP (Partial Chromosome Paints) (Bari)
  • Positional Cloning Project (Berlin Dahlem)
  • Mouse homology - OMIM - NCBI
  • Cancer GeneWeb
  • GeneCards (Weizmann)
  • Human Proteomics Initiative (Expasy)

    • Genes

    Annotated genes
    Ordered by Name Ordered by Location
     Kb pter-qter
    AKAP12 151603.202 6q24-q25
    CAGE1 7271.886 6p24.3
    CDKN1A 36754.437 6p21.1
    CTGF 132311.010 6q23.2
    DDX43 74161.192 6q12-q13
    DEK 18332.379 6p22.3
    E2F3 20510.116 6p22
    EPHA7 94007.860 6q16.1
    FANCE 35528.116 6p22-p21
    FGFR1OP 167332.806 6q27
    FOXO3 108988.762 6q21
    HFE 26195.488 6p21.3
    HMGA1 34312.628 6p21
    ID4 19945.596 6p22.3
    IGF2R 160310.121 6q25-q27
    LTA 31648.072 6p21.3
    MLLT4 167970.520 6q27
    PIM1 37245.964 6p21
    PLAGL1 144303.130 6q24-q25
    POLH 43651.856 6p21
    RNASET2 167262.994 6q27
    RUNX2 45404.032 6p21
    SMAP1 71434.200 6q12-q13
    TFEB 41759.694 6p21
    THBS2 169357.800 6q27
    TNF 31651.329 6p21.3
    WISP3 112481.971 6q21
    Other genes
    possibly implicated
    in cancer
    Ordered by Name Ordered by Location
     Kb pter-qter
    ABCC10 43507.467 6p12.3
    ABCF1 30647.149 6p21.33
    ACAT2 160102.979 6q25.3-q26
    AGER 32256.724 6p21.3
    AIF1 31691.012 6p21.3
    AIG1 143423.716 6q24.1
    AIM1 107066.423 6q21
    AKAP7 131613.197 6q23
    AMD1 111302.681 6q21-q22
    APOM 31731.650 6p21.33
    ARG1 131936.058 6q23
    ARHGAP18 129939.933 6q23.1
    ASF1A 119263.628 6q22.31
    BACH2 90692.969 6q15
    BAG2 57145.293 6p12.3-p11.2
    BAI3 69402.353 6q12
    BAK1 33648.301 6p21.31
    BAT1 31605.975 6p21.3
    BAT3 31714.784 6p21.3
    BCLAF1 136619.694 6q22-q23
    BMP5 55728.196 6p12.1
    BMP6 7672.010 6p24-p23
    BRD2 33046.656 6p21.3
    BVES 105651.392 6q21
    BYSL 41996.943 6p21.1
    C6orf173 126702.971 6q22.32
    C6orf66 97445.609 6q16.3
    CAP2 17501.715 6p22.3
    CASP8AP2 90596.379 6q15
    CCDC28A 139136.350 6q23.1-q24.1
    CCNC 100096.984 6q21
    CCND3 42010.649 6p21
    CCR6 167445.285 6q27
    CD109 74462.235 6q14.1
    CD164 109794.414 6q21
    CD83 14225.844 6p23
    CDC2L6 111037.874 6q21
    CDC5L 44463.280 6p21
    CGA 87851.941 6q12-q21
    CITED2 139735.090 6q23.3
    CNR1 88906.304 6q14-q15
    COL11A2 33238.447 6p21.3
    COX7A2 76004.223 6q14.1
    CRISP2 49768.031 6p12.3
    CRISP3 49803.054 6p12.3
    CSNK2B 31741.636 6p21.3
    CUL7 43113.333 6p21.1
    CYP21A2 32114.061 6p21.3
    DACT2 168450.433 6q27
    DAXX 33394.379 6p21.3
    DCDC2 24279.962 6p22.1
    DDR1 30959.840 6p21.33
    DEF6 35373.573 6p21.33-p21.1
    DHX16 30728.886 6p21.3
    DLL1 170433.219 6q27
    DSE 116707.976 6q22
    DSP 7486.869 6pter-p21
    DST 56587.339 6p12.1
    DUSP22 237.101 6pter-q22.33
    EDN1 12398.515 6p24.1
    EEF1A1 74282.194 6q14.1
    EEF1E1 8024.638 6p24.3
    EFHC1 52392.953 6p12.3
    ENPP1 132170.849 6q22-q23
    ENPP3 132000.135 6q22
    EPM2A 145988.133 6q24
    ESR1 152170.507 6q25.1
    ETV7 36441.949 6p21
    EXOC2 430.138 6p25.3
    EZR 159106.761 6q25.3
    F13A1 6089.310 6p25.3-p24.3
    FABP7 123142.345 6q22-q23
    FAM46A 82512.166 6q14
    FBXO30 146160.965 6q24
    FBXO5 153333.351 6q25-q26
    FGD2 37081.401 6p21.2
    FKBP5 35649.345 6p21.31
    FNDC1 159510.417 6q25
    FOXC1 1555.680 6p25
    FOXF2 1335.068 6p25.3
    FOXP4 41622.142 6p21.1
    FOXQ1 1257.675 6p25
    FRK 116369.386 6q21-q22.3
    FYN 112089.178 6q21
    GABBR1 29677.984 6p21.31
    GCLC 53470.099 6p12
    GJA1 121798.444 6q22-q23
    GLO1 38751.680 6p21.3-p21.1
    GLP1R 39124.535 6p21
    GMNN 24883.143 6p21.32
    GNMT 43036.478 6p12
    GOPC 117988.126 6q21
    GPLD1 24536.384 6p22.1
    GPX5 28601.768 6p22.1
    GRM1 146390.475 6q24
    GRM4 34097.606 6p21.3
    GSTA1 52764.347 6p12
    GSTA2 52723.140 6p12.2
    GSTA3 52869.403 6p12
    GSTA4 52950.710 6p12.1
    GTF2H4 30983.956 6p21.3
    GTF2H5 158511.489 6q25.3
    HACE1 105282.661 6q21
    HCRP1 42434.507 -
    HDAC2 114364.020 6q21
    HECA 139497.942 6q23-q24
    HEY2 126112.425 6q21
    HIST1H1A 26125.239 6p22.1
    HIST1H2AC 26232.352 6p22.1
    HIST1H4I 27215.067 6p22.1
    HLA-A 30018.310 6p21.3
    HLA-B 31429.628 6p21.3
    HLA-C 31344.508 6p21.3
    HLA-DOA 33079.938 6p21.3
    HLA-DOB 32888.518 6p21.3
    HLA-DPB1 33151.738 6p21.3
    HLA-DQA1 32713.161 6p21.3
    HLA-DQB1 32735.635 6p21.3
    HLA-DRA 32515.625 6p21.3
    HLA-DRB1 32654.525 6p21.3
    HLA-E 30565.250 6p21.3
    HLA-G 29902.735 6p21.3
    HMGN3 79967.681 6q14.1
    HMGN4 26646.551 6p21.3
    HSD17B8 33280.397 6p21.3
    HSF2 122762.494 6q22.31
    HSP90AB1 44322.827 6p12
    HSPA1A 31891.270 6p21.3
    HSPA1B 31903.491 6p21.3
    HSPA1L 31885.375 6p21.3
    HULC 8597.440 6p24.3
    HUS1B 600.939 6p25.3
    ICK 52974.057 6p12.3-p11.2
    IER3 30818.955 6p21.3
    IFNGR1 137560.314 6q23.3
    IHPK3 33797.421 6p21.31
    IL17A 52159.144 6p12
    IL17F 52209.443 6p12
    IRF4 336.752 6p25-p23
    ITPR3 33697.139 6p21.31
    IYD 150731.721 6q25.1
    JARID2 15354.506 6p24-p23
    KHDRBS2 62447.824 6
    KIAA1244 138524.917 6q23.3
    KPNA5 117109.060 6q22.2
    LAMA4 112535.827 6q21
    LATS1 150023.744 6q25.1
    LIN28B 105511.616 6q21
    LPA 160872.505 6q26
    LST1 31661.950 6p21.3
    LTB 31656.315 6p21.3
    MAD2L1BP 43705.257 6p21.1
    MAK 10870.942 6p24
    MAP3K4 161332.812 6q26
    MAP3K5 136919.880 6q22.33
    MAP3K7 91282.074 6q15
    MAP3K7IP2 149680.756 6q25.1-q25.3
    MAP7 136705.565 6q23.3
    MAPK13 36206.240 6p21
    MAPK14 36103.432 6p21.3-p21.2
    MAS1 160247.964 6q24-q27
    MAS1L 29562.522 6p21
    MCM3 52236.771 6p12
    MDC1 30775.563 6pter-p21.31
    MED23 131949.566 6q22.33-q24.1
    MEP1A 46869.053 6p12-p11
    MICA 31479.350 6p21.3
    MICB 31573.834 6p21.3
    MIRN206 52117.106 6
    MRS2 24511.132 6p22.3-p22.1
    MSH5 31815.753 6p21.3
    MTCH1 37043.895 6pter-p24.1
    MTHFD1L 151228.384 6q25.1
    MYB 135544.146 6q22-q23
    MYCT1 153060.723 6q25.1
    MYO6 76515.629 6q14.1
    NCOA7 126153.694 6q22.33
    NCR2 41411.506 6p21.1
    NCR3 31664.651 6p21.3
    NEDD9 11291.519 6p25-p24
    NEU1 31934.808 6p21
    NFKBIE 44333.881 6p21.1
    NFYA 41148.688 6p21.3
    NKAIN2 124166.768 6q21
    NOTCH4 32270.598 6p21.3
    NOX3 155758.196 6q25.3
    NQO2 2945.066 6pter-q12
    NRN1 5943.232 6p25.1
    NRSN1 24234.393 6p22.1
    NT5E 86216.021 6q14-q21
    NUP153 17723.248 6p22.3
    OPRM1 154402.136 6q24-q25
    ORC3L 88356.562 6q
    PACRG 163068.154 6q26
    PARC 43257.900 6p21.1
    PARK2 161688.580 6q25.2-q27
    PBOV1 138578.820 6q23-q24
    PBX2 32260.488 6p21.32
    PCMT1 150112.658 6q22.3-q24
    PDCD2 170728.375 6q27
    PDE10A 165660.768 6q26
    PDSS2 107580.454 6q21
    PEX6 43039.589 6p22-p11
    PFDN6 33365.356 6p21.3
    PGC 41812.430 6pter-p21.1
    PHF1 33486.934 6p21.3
    PI16 37030.187 6p21.31
    PKIB 122973.076 6q22.31
    PLG 161043.264 6q26
    POU3F2 99389.301 6q16.2
    POU5F1 31240.093 6p21.33
    PPARD 35418.313 6p21.2
    PPP1R10 30676.161 6p21.3
    PPP1R11 30142.911 6p21.3
    PPP1R14C 150505.881 6q24.3-q25.3
    PPP2R5D 43060.308 6p21.1
    PRDM1 106640.888 6q21-q22.1
    PRICKLE4 41856.478 6p21.31
    PRIM2 57290.381 6p12-p11.1
    PRL 22395.459 6p22.2-p21.3
    PRPF4B 3966.568 6p25.2
    PRPH2 42772.311 6p21.2-cen
    PSMB8 32916.472 6p21.3
    PSMB9 32929.916 6p21.3
    PTCRA 42991.705 6p21.3
    PTK7 43152.007 6p21.1-p12.2
    PTP4A1 64339.879 6q12
    PTPRK 128331.625 6q22.2-q22.3
    QKI 163755.665 6q26
    QRSL1 107184.146 6q21
    RAB23 57161.541 6p12.1
    RAB32 146906.521 6q24.3
    RAET1E 150251.294 6q24.3
    RANBP9 13729.709 6p23
    RCAN2 46296.428 6p12.3
    REPS1 139267.313 6q24.1
    REV3L 111726.927 6q21
    RGL2 33367.414 6p21.3
    RGS17 153373.725 6q25-q26
    RING1 33284.264 6p21.3
    RIOK1 7335.061 6p24.3
    RIPK1 3022.057 6p25.2
    RNF144B 18495.573 6p22.3
    RNF146 127629.713 6q22.1-q22.33
    RNF39 30146.022 6p21.3
    RNF5 32254.140 6p21.31
    RNF8 37429.726 6p21.3
    ROS1 117716.223 6q22
    RPL10A 35544.156 6p21.31
    RPS10 34493.209 6p21.31
    RPS12 133177.401 6q23.2
    RPS6KA2 166742.844 6q27
    RRAGD 90134.313 6q15-q16
    RXRB 33269.343 6p21.3
    SASH1 148705.422 6q24.3
    SCGN 25760.408 6p22.3-p22.1
    SEC63 108295.653 6q21
    SENP6 76368.342 6q13-q14.3
    SERINC1 122806.192 6q22.32
    SERPINB9 2832.503 6p25
    SESN1 109414.338 6q21
    SFRS18 99954.562 6q16.3
    SFRS3 36670.068 6p21
    SGK1 134532.077 6q23
    SHPRH 146247.637 6q24.2
    SKIV2L 32034.560 6p21
    SLC22A16 110852.601 6q21
    SLC22A2 160557.782 6q25.3
    SLC29A1 44295.220 6p21.1
    SMPDL3A 123151.670 6q22.32
    SNHG5 86443.516 6q14.3
    SNX3 108639.410 6q21
    SOD2 160022.745 6q25
    SOX4 21701.951 6p22.3
    SPDEF 34613.558 6p21.3
    SRF 43246.898 6p
    SRPK1 35908.789 6p21.31
    SSR1 7226.287 6p24.3
    STK19 32047.625 6p21.3
    STK38 36569.647 6p21
    STL 125271.087 6q22.33
    SUPT3H 44905.428 6p21.1-p12.3
    SYNE1 152484.515 6q25
    SYNJ2 158322.907 6q25.3
    T 166491.076 6q27
    TAP1 32920.964 6p21.3
    TAP2 32901.165 6p21.3
    TAPBP 33375.450 6p21.3
    TBCC 42820.212 6p21.1
    TBP 170705.396 6q27
    TBX18 85500.876 6q14-q15
    TCF21 134251.970 6pter-qter
    TFAP2A 10504.902 6pter-p22.3
    TFAP2B 50894.398 6p12
    TIAM2 155579.789 6q25.2
    TNFAIP3 138230.274 6q23-q25
    TNFRSF21 47307.227 6p21.1
    TNXB 32116.911 6p21.3
    TPBG 83130.258 6q14-q15
    TPD52L1 125517.119 6q22-q23
    TPMT 18236.524 6p22.3
    TRAF3IP2 111986.836 6q21
    TRAM2 52470.159 6p21.1-p12
    TRERF1 42303.842 6p21.1-p12.1
    TRIM26 30260.211 6p21.3
    TRIM27 28978.758 6p22
    TSG1 94473.521 6q16.1
    TTBK1 43319.200 6p21.1
    TTK 80771.078 6q13-q21
    TTRAP 24758.184 6p22.3-p22.1
    TUBB 30796.136 6p21.33
    TUBB2A 3098.901 6p25.2
    TUBB2B 3169.514 6p25.2
    TXNDC5 7826.751 6p24.3
    UBD 29631.387 6p21.3
    UBE2J1 90093.063 6q16.1
    ULBP2 150304.829 6q25
    UNC93A 167624.891 6q27
    UST 149109.964 6q25.1
    UTRN 144654.566 6q24
    VARS2 30989.961 6p21.33
    VEGFA 43845.931 6p12
    VIP 153113.626 6q25
    WRNIP1 2710.665 6p25.2
    WTAP 160068.142 6q25-q27
    XPO5 43598.051 6p21.1
    ZKSCAN3 28425.670 6p22.1
    ZNF451 57062.787 6p12.1
    ZNRD1 30137.015 6p21.3

    GeneCards   GDB - List of genes

    This page should be referenced as such :
    Dessen P, Knuutila S, Huret JL Chromosome 6. Atlas Genet Cytogenet Oncol Haematol. 2002.
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_6.html
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : Sat Nov 8 19:45:37 2008
    Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case reports   Journals   Portal   Teaching   

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