| Clinics and Pathology |
| Disease | Myeloid malignancies |
| Epidemiology | Only 2 cases to date, a 62-year-old male patient with a refractory anemia with excess of blasts (RAEB), and a patient with a treatment related myelodysplastic syndrome evolving to overt leukaemia (Davis et al., 1984; Olney et al., 2002). |
| Prognosis | The patient with RAEB died one month after diagnosis. |
| Cytogenetics |
| Additional anomalies | The patient with RAEB also had a del(7q) and a del(20q). |
| Genes involved and Proteins |
| Note | The genes involved in this anomaly are unknown. |
| External links |
| Other database | inv(6)(p15q13) | Mitelman database (CGAP - NCBI) |
| To be noted |
| Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
| Bibliography |
| Hematologic manifestations associated with deletions of the long arm of chromosome 20. |
| Davis MP, Dewald GW, Pierre RV, Hoagland HC. |
| Cancer Genet Cytogenet. 1984 May;12(1):63-71. |
| PMID 6713360 |
| Unique balanced chromosome abnormalities in treatment-related myelodysplastic syndromes and acute myeloid leukemia: report from an international workshop. |
| Olney HJ, Mitelman F, Johansson B, Mrozek K, Berger R, Rowley JD. |
| Genes Chromosomes Cancer. 2002 Apr;33(4):413-23. |
| PMID 11921275 |
| Contributor(s) |
| Written | 11-2008 | Jean-Loup Huret |
| Genetics, Dept Medical Information, University of Poitiers; CHU Poitiers Hospital, F-86021 Poitiers, France |
| Citation |
| This paper should be referenced as such : |
| Huret JL . inv(6)(p15q13). Atlas Genet Cytogenet Oncol Haematol. November 2008 . URL : http://AtlasGeneticsOncology.org/Anomalies/inv06p15q13ID1529.html |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sat Feb 6 15:45:14 CET 2010 |
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