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t(6;8)(q11;q11)

Clinics and Pathology

Disease Diffuse large B-cell lymphoma (DLBCL)
Epidemiology only 2 cases so far, aaged 42 and 57 yrs; 2 female patients
Prognosis one patient is alive at 12 mths+, the other one died at 31 mths.

Cytogenetics

Cytogenetics Morphological the anomaly had been uncovered by SKY
  the unbalanced form der(6)t(6;8) was found in the two cases

Genes involved and Proteins

Note genes involved are yet unknown

External links

Other databaset(6;8)(q11;q11) Mitelman database (CGAP - NCBI)
Other databaset(6;8)(q11;q11) CancerChromosomes (NCBI)

To be noted

Additional cases are needed to delineate the epidemiology of this rare entity:
you are welcome to submit a paper to our new Case Report section.

Bibliography

Spectral karyotyping identifies new rearrangements, translocations, and clinical associations in diffuse large B-cell lymphoma.
Nanjangud G, Rao PH, Hegde A, Teruya-Feldstein J, Donnelly G, Qin J, Jhanwar SC, Zelenetz AD, Chaganti RS
Blood. 2002 ; 99 (7) : 2554-2561.
PMID 11895793
 

Contributor(s)

Written07-2002Jean-Loup Huret

Citation

This paper should be referenced as such :
Huret JL . t(6;8)(q11;q11). Atlas Genet Cytogenet Oncol Haematol. July 2002 .
URL : http://AtlasGeneticsOncology.org/Anomalies/t0608q11q11ID1253.html

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon May 12 18:12:28 2008


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