| Nomenclature | | HGNC | MLLT4 7137 |
| Entrez_Gene | MLLT4 4301 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| Cards |
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| Atlas | AF6 |
| GeneCards | MLLT4 |
| Ensembl | MLLT4 [Search_View] ENSG00000130396 [Gene_View] |
| Genatlas | MLLT4 |
| GeneLynx | MLLT4 |
| eGenome | MLLT4 |
| euGene | 4301 |
| Genomic and cartography |
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| GoldenPath | MLLT4 - 6q27 chr6:167970520-168108564 + 6q27 [Description] (hg18-Mar_2006) |
| Ensembl | MLLT4 - 6q27 [CytoView] |
| NCBI | Mapview |
| OMIM | Disease map [OMIM] |
| HomoloGene | MLLT4 |
| Gene and transcription | | Genbank | AB209420 [ ENTREZ ] |
| Genbank | AF085836 [ ENTREZ ] |
| Genbank | AK055689 [ ENTREZ ] |
| Genbank | AK091815 [ ENTREZ ] |
| Genbank | AL161973 [ ENTREZ ] |
| RefSeq | NM_001040000 [ SRS ] NM_001040000 [ ENTREZ ] |
| RefSeq | NM_001040001 [ SRS ] NM_001040001 [ ENTREZ ] |
| RefSeq | NM_005936 [ SRS ] NM_005936 [ ENTREZ ] |
| RefSeq | AC_000049 [ SRS ] AC_000049 [ ENTREZ ] |
| RefSeq | AC_000138 [ SRS ] AC_000138 [ ENTREZ ] |
| RefSeq | NC_000006 [ SRS ] NC_000006 [ ENTREZ ] |
| RefSeq | NT_007302 [ SRS ] NT_007302 [ ENTREZ ] |
| RefSeq | NW_001838994 [ SRS ] NW_001838994 [ ENTREZ ] |
| RefSeq | NW_923184 [ SRS ] NW_923184 [ ENTREZ ] |
| AceView | MLLT4 AceView - NCBI |
| Unigene | Hs.709178 [ SRS ] Hs.709178 [ NCBI ]
HS709178 [ spliceNest ] |
| Fast-db | 17058 (alternative variants) |
| Protein : pattern, domain, 3D structure |
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| SwissProt | P55196 [ SRS] P55196 [ EXPASY ] P55196 [ INTERPRO ] P55196 [ UNIPROT ] |
| Prosite | PS51126 DILUTE [ SRS ] PS51126 DILUTE [ Expasy ] |
| Prosite | PS50006 FHA_DOMAIN [ SRS ] PS50006 FHA_DOMAIN [ Expasy ] |
| Prosite | PS50106 PDZ [ SRS ] PS50106 PDZ [ Expasy ] |
| Prosite | PS50200 RA [ SRS ] PS50200 RA [ Expasy ] |
| Interpro | IPR002710 DIL [ SRS ] IPR002710 DIL [ EBI ] |
| Interpro | IPR000253 FHA [ SRS ] IPR000253 FHA [ EBI ] |
| Interpro | IPR001478 PDZ [ SRS ] IPR001478 PDZ [ EBI ] |
| Interpro | IPR000159 Ras-assoc [ SRS ] IPR000159 Ras-assoc [ EBI ] |
| CluSTr | P55196 |
| Pfam | PF01843 DIL [ SRS ] PF01843 DIL [ Sanger ] pfam01843 [ NCBI-CDD ] |
| Pfam | PF00498 FHA [ SRS ] PF00498 FHA [ Sanger ] pfam00498 [ NCBI-CDD ] |
| Pfam | PF00595 PDZ [ SRS ] PF00595 PDZ [ Sanger ] pfam00595 [ NCBI-CDD ] |
| Pfam | PF00788 RA [ SRS ] PF00788 RA [ Sanger ] pfam00788 [ NCBI-CDD ] |
| Smart | SM00240 FHA [EMBL] |
| Smart | SM00228 PDZ [EMBL] |
| Smart | SM00314 RA [EMBL] |
| Prodom | PD003376 DIL[INRA-Toulouse] |
| Prodom | P55196 AFAD_HUMAN [ Domain structure ] P55196 AFAD_HUMAN [ sequences sharing at least 1 domain ] |
| Blocks | P55196 |
| PDB | 1T2M [ SRS ] 1T2M [ PdbSum ], 1T2M [ IMB ] 1T2M [ RSDB ] |
| PDB | 1XZ9 [ SRS ] 1XZ9 [ PdbSum ], 1XZ9 [ IMB ] 1XZ9 [ RSDB ] |
| PDB | 2AIN [ SRS ] 2AIN [ PdbSum ], 2AIN [ IMB ] 2AIN [ RSDB ] |
| PDB | 2EXG [ SRS ] 2EXG [ PdbSum ], 2EXG [ IMB ] 2EXG [ RSDB ] |
| HPRD | 01164 |
| Protein Interaction databases |
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| DIP | P55196 |
| IntAct | P55196 |
| Polymorphism : SNP, mutations, diseases |
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| OMIM | 159559 [ map ] |
| GENECLINICS | 159559 |
| SNP | MLLT4 [dbSNP-NCBI] |
| SNP | NM_001040000 [SNP-NCI] |
| SNP | NM_001040001 [SNP-NCI] |
| SNP | NM_005936 [SNP-NCI] |
| SNP | MLLT4 [GeneSNPs - Utah] MLLT4] [HGBASE - SRS] |
| HAPMAP | MLLT4 [HAPMAP] |
| COSMIC | MLLT4 [Somatic mutation (COSMIC-CGP-Sanger)] |
| TICdb | MLLT4 [Translocation breakpoints In Cancer] |
| HGMD | MLLT4 |
| General knowledge |
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| Family Browser | MLLT4 [UCSC Family Browser] |
| SOURCE | NM_001040000 |
| SOURCE | NM_001040001 |
| SOURCE | NM_005936 |
| SMD | Hs.709178 |
| SAGE | Hs.709178 |
| GO | molecular_function [Amigo] molecular_function |
| GO | protein binding [Amigo] protein binding |
| GO | cellular_component [Amigo] cellular_component |
| GO | intercellular junction [Amigo] intercellular junction |
| GO | cell adhesion [Amigo] cell adhesion |
| GO | signal transduction [Amigo] signal transduction |
| GO | signal transduction [Amigo] signal transduction |
| GO | cell-cell signaling [Amigo] cell-cell signaling |
| GO | protein C-terminus binding [Amigo] protein C-terminus binding |
| GO | biological_process [Amigo] biological_process |
| KEGG | Adherens junction |
| KEGG | Tight junction |
| KEGG | Leukocyte transendothelial migration |
| PubGene | MLLT4 |
| TreeFam | MLLT4 |
| CTD | 4301 [Comparative ToxicoGenomics Database] |
| Other databases |
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| Probes |
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| Probe | Cancer Cytogenetics (Bari) |
| Probe | MLLT4 Related clones (RZPD - Berlin) |
| PubMed |
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| PubMed | 48 Pubmed reference(s) in Entrez |
| Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation. |
| Prasad R, Gu Y, Alder H, Nakamura T, Canaani O, Saito H, Huebner K, Gale RP, Nowell PC, Kuriyama K |
| Cancer research. 1993 ; 53 (23) : 5624-5628. |
| PMID 8242616 |
| |
| Chromosome abnormalities in leukaemia: the 11q23 paradigm. |
| Young BD, Saha V |
| Cancer surveys. 1996 ; 28 : 225-245. |
| PMID 8977038 |
| |
| Molecular basis of 11q23 rearrangements in hematopoietic malignant proliferations. |
| Bernard OA, Berger R |
| Genes, chromosomes & cancer. 1995 ; 13 (2) : 75-85. |
| PMID 7542910 |
| |
| 11q23 rearrangements in acute leukemia. |
| Rubnitz JE, Behm FG, Downing JR |
| Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 1996 ; 10 (1) : 74-82. |
| PMID 8558942 |
| |
