ACSL4 (acyl-CoA synthetase long-chain family member 4)

Identity

Other names	ACS4
	FACL4
	LACS4
	MRX63
	MRX68
Hugo	ACSL4
Location	Xq22.3-q23
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	ACSL4
GDB	ACSL4
Entrez_Gene	ACSL4  2182  acyl-CoA synthetase long-chain family member 4
	Cards
GeneCards	ACSL4
Ensembl	ACSL4 [Search_View]   ENSG00000068366 [Gene_View]
Genatlas	ACSL4
GeneLynx	ACSL4
eGenome	ACSL4
euGene	2182
	Genomic and cartography
GoldenPath	ACSL4  -     chrX:108771222-108863275 -  Xq22.3    (hg18-March_2006)
Ensembl	ACSL4 - Xq22.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ACSL4
	Gene and transcription
Genbank	AB061713 [ ENTREZ ]
Genbank	AB061714 [ ENTREZ ]
Genbank	AF030555 [ ENTREZ ]
Genbank	AK292070 [ ENTREZ ]
Genbank	BC034959 [ ENTREZ ]
RefSeq	NM_004458 [ SRS ]    NM_004458 [ ENTREZ ]
RefSeq	NM_022977 [ SRS ]    NM_022977 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_011651 [ SRS ]    NT_011651 [ ENTREZ ]
RefSeq	NW_927717 [ SRS ]    NW_927717 [ ENTREZ ]
AceView	ACSL4 AceView - NCBI
Unigene	Hs.268785 [ SRS ]    Hs.268785 [ NCBI ]     HS268785 [ spliceNest ]
Fast-db	13635 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O60488 [ SRS]    O60488 [ EXPASY ]     O60488 [ INTERPRO ]
Prosite	PS00455 AMP_BINDING [ SRS ]    PS00455 AMP_BINDING [ Expasy ]
Interpro	IPR000873 AMP-dep_Synth/Lig [ SRS ]    IPR000873 AMP-dep_Synth/Lig [ EBI ]
CluSTr	O60488
Pfam	PF00501 AMP-binding [ SRS ]    PF00501 AMP-binding [ Sanger ]    pfam00501 [ NCBI-CDD ]
Blocks	O60488
HPRD	02152
	Protein Interaction databases
DIP	O60488
IntAct	O60488
	Polymorphism : SNP, mutations, diseases
OMIM	300157;300387    [ map ]
GENECLINICS	300157;300387
SNP	ACSL4 [dbSNP-NCBI]
SNP	NM_004458 [SNP-NCI]
SNP	NM_022977 [SNP-NCI]
SNP	ACSL4 [GeneSNPs - Utah]  ACSL4] [HGBASE - SRS]
HAPMAP	ACSL4 [HAPMAP]
COSMIC	ACSL4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ACSL4
	General knowledge
Family Browser	ACSL4 [UCSC Family Browser]
SOURCE	NM_004458
SOURCE	NM_022977
SMD	Hs.268785
SAGE	Hs.268785
Enzyme	6.2.1.3 [ Enzyme-SRS ]   6.2.1.3 [ Brenda-SRS ]   6.2.1.3 [ KEGG ]   6.2.1.3 [ WIT ]
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	long-chain-fatty-acid-CoA ligase activity [Amigo]  long-chain-fatty-acid-CoA ligase activity
GO	mitochondrion [Amigo]  mitochondrion
GO	mitochondrial outer membrane [Amigo]  mitochondrial outer membrane
GO	peroxisome [Amigo]  peroxisome
GO	peroxisomal membrane [Amigo]  peroxisomal membrane
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	endoplasmic reticulum membrane [Amigo]  endoplasmic reticulum membrane
GO	microsome [Amigo]  microsome
GO	lipid metabolic process [Amigo]  lipid metabolic process
GO	fatty acid metabolic process [Amigo]  fatty acid metabolic process
GO	learning and/or memory [Amigo]  learning and/or memory
GO	metabolic process [Amigo]  metabolic process
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	ligase activity [Amigo]  ligase activity
KEGG	Fatty acid metabolism
KEGG	PPAR signaling pathway
KEGG	Adipocytokine signaling pathway
PubGene	ACSL4
	Other databases
	Probes
Probe	ACSL4 Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

BiblioGene - INIST
Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Apr 17 08:39:01 2008