ADAM33 (ADAM metallopeptidase domain 33)

Identity

Other names	DJ964F7.1
	DKFZp434K0521
	FLJ35308
	FLJ36751
	MGC149823
	MGC71889
Hugo	ADAM33
Location	20p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	ADAM33
GDB	ADAM33
Entrez_Gene	ADAM33  80332  ADAM metallopeptidase domain 33
	Cards
GeneCards	ADAM33
Ensembl	ADAM33 [Search_View]   ENSG00000149451 [Gene_View]
Genatlas	ADAM33
GeneLynx	ADAM33
eGenome	ADAM33
euGene	80332
	Genomic and cartography
GoldenPath	ADAM33  -  20p13   chr20:3596621-3610738 -  20p13   [Description]    (hg18-March_2006)
Ensembl	ADAM33 - 20p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ADAM33
	Gene and transcription
Genbank	AB055891 [ ENTREZ ]
Genbank	AF466287 [ ENTREZ ]
Genbank	AF466289 [ ENTREZ ]
Genbank	AK092627 [ ENTREZ ]
Genbank	AK094070 [ ENTREZ ]
RefSeq	NM_025220 [ SRS ]    NM_025220 [ ENTREZ ]
RefSeq	NM_153202 [ SRS ]    NM_153202 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	ADAM33 AceView - NCBI
Unigene	Hs.173716 [ SRS ]    Hs.173716 [ NCBI ]     HS173716 [ spliceNest ]
Fast-db	3489 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9BZ11 [ SRS]    Q9BZ11 [ EXPASY ]     Q9BZ11 [ INTERPRO ]
Prosite	PS50215 ADAM_MEPRO [ SRS ]    PS50215 ADAM_MEPRO [ Expasy ]
Prosite	PS00546 CYSTEINE_SWITCH [ SRS ]    PS00546 CYSTEINE_SWITCH [ Expasy ]
Prosite	PS00427 DISINTEGRIN_1 [ SRS ]    PS00427 DISINTEGRIN_1 [ Expasy ]
Prosite	PS50214 DISINTEGRIN_2 [ SRS ]    PS50214 DISINTEGRIN_2 [ Expasy ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS00142 ZINC_PROTEASE [ SRS ]    PS00142 ZINC_PROTEASE [ Expasy ]
Interpro	IPR006586 ADAM_cysteine [ SRS ]    IPR006586 ADAM_cysteine [ EBI ]
Interpro	IPR001762 Blood-coag_inhib_Disintegrin [ SRS ]    IPR001762 Blood-coag_inhib_Disintegrin [ EBI ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR013111 EGF_extracell [ SRS ]    IPR013111 EGF_extracell [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR001818 Pept_M10A_M12B [ SRS ]    IPR001818 Pept_M10A_M12B [ EBI ]
Interpro	IPR006025 Pept_M_Zn_BS [ SRS ]    IPR006025 Pept_M_Zn_BS [ EBI ]
Interpro	IPR001590 Peptidase_M12B [ SRS ]    IPR001590 Peptidase_M12B [ EBI ]
Interpro	IPR002870 Peptidase_M12B_N [ SRS ]    IPR002870 Peptidase_M12B_N [ EBI ]
CluSTr	Q9BZ11
Pfam	PF08516 ADAM_CR [ SRS ]    PF08516 ADAM_CR [ Sanger ]    pfam08516 [ NCBI-CDD ]
Pfam	PF00200 Disintegrin [ SRS ]    PF00200 Disintegrin [ Sanger ]    pfam00200 [ NCBI-CDD ]
Pfam	PF07974 EGF_2 [ SRS ]    PF07974 EGF_2 [ Sanger ]    pfam07974 [ NCBI-CDD ]
Pfam	PF01562 Pep_M12B_propep [ SRS ]    PF01562 Pep_M12B_propep [ Sanger ]    pfam01562 [ NCBI-CDD ]
Pfam	PF01421 Reprolysin [ SRS ]    PF01421 Reprolysin [ Sanger ]    pfam01421 [ NCBI-CDD ]
Smart	SM00608 ACR [EMBL]
Smart	SM00050 DISIN [EMBL]
Smart	SM00181 EGF [EMBL]
Prodom	PD000664 Disintegrin[INRA-Toulouse]
Prodom	Q9BZ11 ADA33_HUMAN [ Domain structure ]   Q9BZ11 ADA33_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q9BZ11
PDB	1R54 [ SRS ]    1R54 [ PdbSum ],   1R54 [ IMB ]   1R54 [ RSDB ]
PDB	1R55 [ SRS ]    1R55 [ PdbSum ],   1R55 [ IMB ]   1R55 [ RSDB ]
HPRD	06173
	Protein Interaction databases
DIP	Q9BZ11
IntAct	Q9BZ11
	Polymorphism : SNP, mutations, diseases
OMIM	607114    [ map ]
GENECLINICS	607114
SNP	ADAM33 [dbSNP-NCBI]
SNP	NM_025220 [SNP-NCI]
SNP	NM_153202 [SNP-NCI]
SNP	ADAM33 [GeneSNPs - Utah]  ADAM33] [HGBASE - SRS]
HAPMAP	ADAM33 [HAPMAP]
COSMIC	ADAM33 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ADAM33
	General knowledge
Family Browser	ADAM33 [UCSC Family Browser]
SOURCE	NM_025220
SOURCE	NM_153202
SMD	Hs.173716
SAGE	Hs.173716
Enzyme	3.4.24.- [ Enzyme-SRS ]   3.4.24.- [ Brenda-SRS ]   3.4.24.- [ KEGG ]   3.4.24.- [ WIT ]
GO	metalloendopeptidase activity [Amigo]  metalloendopeptidase activity
GO	metalloendopeptidase activity [Amigo]  metalloendopeptidase activity
GO	proteolysis [Amigo]  proteolysis
GO	proteolysis [Amigo]  proteolysis
GO	integrin-mediated signaling pathway [Amigo]  integrin-mediated signaling pathway
GO	metallopeptidase activity [Amigo]  metallopeptidase activity
GO	zinc ion binding [Amigo]  zinc ion binding
GO	zinc ion binding [Amigo]  zinc ion binding
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	metal ion binding [Amigo]  metal ion binding
PubGene	ADAM33
TreeFam	ADAM33
CTD	80332 [Comparative Genomics Database]
	Other databases
	Probes
Probe	ADAM33 Related clones (RZPD - Berlin)
	PubMed
PubMed	28 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 19:54:36 2008