ADORA2A (adenosine A2a receptor)

Identity

Other names	ADORA2
	RDC8
	hA2aR
HGNC	ADORA2A
Location	22q11.23
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	ADORA2A   263
Entrez_Gene	ADORA2A  135  adenosine A2a receptor
	Cards
GeneCards	ADORA2A
Ensembl	ADORA2A [Search_View]   ENSG00000128271 [Gene_View]
Genatlas	ADORA2A
GeneLynx	ADORA2A
eGenome	ADORA2A
euGene	135
	Genomic and cartography
GoldenPath	ADORA2A  -  22q11.23   chr22:23153530-23168325 +  22q11.23   [Description]    (hg18-March_2006)
Ensembl	ADORA2A - 22q11.23 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ADORA2A
	Gene and transcription
Genbank	AK123058 [ ENTREZ ]
Genbank	AK289871 [ ENTREZ ]
Genbank	AK312946 [ ENTREZ ]
Genbank	AY136747 [ ENTREZ ]
Genbank	BC013780 [ ENTREZ ]
RefSeq	NM_000675 [ SRS ]    NM_000675 [ ENTREZ ]
RefSeq	AC_000065 [ SRS ]    AC_000065 [ ENTREZ ]
RefSeq	AC_000154 [ SRS ]    AC_000154 [ ENTREZ ]
RefSeq	NC_000022 [ SRS ]    NC_000022 [ ENTREZ ]
RefSeq	NT_011520 [ SRS ]    NT_011520 [ ENTREZ ]
RefSeq	NW_001838745 [ SRS ]    NW_001838745 [ ENTREZ ]
RefSeq	NW_927628 [ SRS ]    NW_927628 [ ENTREZ ]
AceView	ADORA2A AceView - NCBI
Unigene	Hs.712771 [ SRS ]    Hs.712771 [ NCBI ]     HS712771 [ spliceNest ]
Fast-db	2841 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P29274 [ SRS]    P29274 [ EXPASY ]     P29274 [ INTERPRO ]     P29274 [ UNIPROT ]
Prosite	PS00237 G_PROTEIN_RECEP_F1_1 [ SRS ]    PS00237 G_PROTEIN_RECEP_F1_1 [ Expasy ]
Prosite	PS50262 G_PROTEIN_RECEP_F1_2 [ SRS ]    PS50262 G_PROTEIN_RECEP_F1_2 [ Expasy ]
Interpro	IPR001513 Adeno_A2A_rcpt [ SRS ]    IPR001513 Adeno_A2A_rcpt [ EBI ]
Interpro	IPR001634 Adenosn_rcpt [ SRS ]    IPR001634 Adenosn_rcpt [ EBI ]
Interpro	IPR000276 GPCR_Rhodpsn [ SRS ]    IPR000276 GPCR_Rhodpsn [ EBI ]
Interpro	IPR017452 GPCR_Rhodpsn_supfam [ SRS ]    IPR017452 GPCR_Rhodpsn_supfam [ EBI ]
CluSTr	P29274
Pfam	PF00001 7tm_1 [ SRS ]    PF00001 7tm_1 [ Sanger ]    pfam00001 [ NCBI-CDD ]
Blocks	P29274
PDB	1MMH [ SRS ]    1MMH [ PdbSum ],   1MMH [ IMB ]   1MMH [ RSDB ]
PDB	1UPE [ SRS ]    1UPE [ PdbSum ],   1UPE [ IMB ]   1UPE [ RSDB ]
HPRD	00043
	Protein Interaction databases
DIP	P29274
IntAct	P29274
	Polymorphism : SNP, mutations, diseases
OMIM	102776    [ map ]
GENECLINICS	102776
SNP	ADORA2A [dbSNP-NCBI]
SNP	NM_000675 [SNP-NCI]
SNP	ADORA2A [GeneSNPs - Utah]  ADORA2A] [HGBASE - SRS]
HAPMAP	ADORA2A [HAPMAP]
HGMD	ADORA2A
	General knowledge
Family Browser	ADORA2A [UCSC Family Browser]
SOURCE	NM_000675
SMD	Hs.712771
SAGE	Hs.712771
GO	rhodopsin-like receptor activity [Amigo]  rhodopsin-like receptor activity
GO	adenosine receptor activity, G-protein coupled [Amigo]  adenosine receptor activity, G-protein coupled
GO	synaptic transmission, dopaminergic [Amigo]  synaptic transmission, dopaminergic
GO	adenosine receptor signaling pathway [Amigo]  adenosine receptor signaling pathway
GO	response to amphetamine [Amigo]  response to amphetamine
GO	receptor activity [Amigo]  receptor activity
GO	membrane fraction [Amigo]  membrane fraction
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	cAMP biosynthetic process [Amigo]  cAMP biosynthetic process
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	neurotransmitter transport [Amigo]  neurotransmitter transport
GO	phagocytosis [Amigo]  phagocytosis
GO	apoptosis [Amigo]  apoptosis
GO	inflammatory response [Amigo]  inflammatory response
GO	cellular defense response [Amigo]  cellular defense response
GO	signal transduction [Amigo]  signal transduction
GO	transmembrane receptor protein tyrosine kinase signaling pathway [Amigo]  transmembrane receptor protein tyrosine kinase signaling pathway
GO	G-protein coupled receptor protein signaling pathway [Amigo]  G-protein coupled receptor protein signaling pathway
GO	G-protein signaling, adenylate cyclase activating pathway [Amigo]  G-protein signaling, adenylate cyclase activating pathway
GO	activation of adenylate cyclase activity [Amigo]  activation of adenylate cyclase activity
GO	cell-cell signaling [Amigo]  cell-cell signaling
GO	central nervous system development [Amigo]  central nervous system development
GO	blood coagulation [Amigo]  blood coagulation
GO	sensory perception [Amigo]  sensory perception
GO	locomotory behavior [Amigo]  locomotory behavior
GO	blood circulation [Amigo]  blood circulation
GO	integral to membrane [Amigo]  integral to membrane
GO	gastric inhibitory peptide receptor activity [Amigo]  gastric inhibitory peptide receptor activity
GO	positive regulation of synaptic transmission, GABAergic [Amigo]  positive regulation of synaptic transmission, GABAergic
GO	eating behavior [Amigo]  eating behavior
KEGG	Calcium signaling pathway
KEGG	Neuroactive ligand-receptor interaction
PubGene	ADORA2A
TreeFam	ADORA2A
CTD	135 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ADORA2A Related clones (RZPD - Berlin)
	PubMed
PubMed	88 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 19:59:15 2008