ADRA1A (adrenergic, alpha-1A-, receptor)

Identity

Other names	ADRA1C
	ADRA1L1
	ALPHA1AAR
HGNC	ADRA1A
Location	8p21.2
Location_base_pair	Starts at 26683139 and ends at 26778839 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ADRA1A   277
Entrez_Gene	ADRA1A  148  adrenergic, alpha-1A-, receptor
	Cards
GeneCards	ADRA1A
Ensembl	ADRA1A [Search_View]   ENSG00000120907 [Gene_View]
Genatlas	ADRA1A
GeneLynx	ADRA1A
eGenome	ADRA1A
euGene	148
	Genomic and cartography
GoldenPath	ADRA1A  -  8p21.2   chr8:26683139-26778839 -  8p21.2   [Description]    (hg18-March_2006)
Ensembl	ADRA1A - 8p21.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ADRA1A
	Gene and transcription
Genbank	AF013261 [ ENTREZ ]
Genbank	AF395806 [ ENTREZ ]
Genbank	AK289548 [ ENTREZ ]
Genbank	AY491775 [ ENTREZ ]
Genbank	AY491776 [ ENTREZ ]
RefSeq	NM_000680 [ SRS ]    NM_000680 [ ENTREZ ]
RefSeq	NM_033302 [ SRS ]    NM_033302 [ ENTREZ ]
RefSeq	NM_033303 [ SRS ]    NM_033303 [ ENTREZ ]
RefSeq	NM_033304 [ SRS ]    NM_033304 [ ENTREZ ]
RefSeq	AC_000051 [ SRS ]    AC_000051 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_023666 [ SRS ]    NT_023666 [ ENTREZ ]
RefSeq	NW_001839127 [ SRS ]    NW_001839127 [ ENTREZ ]
RefSeq	NW_923907 [ SRS ]    NW_923907 [ ENTREZ ]
AceView	ADRA1A AceView - NCBI
Unigene	Hs.709175 [ SRS ]    Hs.709175 [ NCBI ]     HS709175 [ spliceNest ]
Fast-db	2911 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P35348 [ SRS]    P35348 [ EXPASY ]     P35348 [ INTERPRO ]     P35348 [ UNIPROT ]
Prosite	PS00237 G_PROTEIN_RECEP_F1_1 [ SRS ]    PS00237 G_PROTEIN_RECEP_F1_1 [ Expasy ]
Prosite	PS50262 G_PROTEIN_RECEP_F1_2 [ SRS ]    PS50262 G_PROTEIN_RECEP_F1_2 [ Expasy ]
Interpro	IPR001004 Adrene_rcpt_A1Cs [ SRS ]    IPR001004 Adrene_rcpt_A1Cs [ EBI ]
Interpro	IPR002233 Adrnrgc_rcpt [ SRS ]    IPR002233 Adrnrgc_rcpt [ EBI ]
Interpro	IPR000276 GPCR_Rhodpsn [ SRS ]    IPR000276 GPCR_Rhodpsn [ EBI ]
Interpro	IPR017452 GPCR_Rhodpsn_supfam [ SRS ]    IPR017452 GPCR_Rhodpsn_supfam [ EBI ]
CluSTr	P35348
Pfam	PF00001 7tm_1 [ SRS ]    PF00001 7tm_1 [ Sanger ]    pfam00001 [ NCBI-CDD ]
Blocks	P35348
HPRD	00081
	Protein Interaction databases
DIP	P35348
IntAct	P35348
	Polymorphism : SNP, mutations, diseases
OMIM	104221    [ map ]
GENECLINICS	104221
SNP	ADRA1A [dbSNP-NCBI]
SNP	NM_000680 [SNP-NCI]
SNP	NM_033302 [SNP-NCI]
SNP	NM_033303 [SNP-NCI]
SNP	NM_033304 [SNP-NCI]
SNP	ADRA1A [GeneSNPs - Utah]  ADRA1A] [HGBASE - SRS]
HAPMAP	ADRA1A [HAPMAP]
HGMD	ADRA1A
	General knowledge
Family Browser	ADRA1A [UCSC Family Browser]
SOURCE	NM_000680
SOURCE	NM_033302
SOURCE	NM_033303
SOURCE	NM_033304
SMD	Hs.709175
SAGE	Hs.709175
GO	rhodopsin-like receptor activity [Amigo]  rhodopsin-like receptor activity
GO	receptor activity [Amigo]  receptor activity
GO	adrenoceptor activity [Amigo]  adrenoceptor activity
GO	alpha1-adrenergic receptor activity [Amigo]  alpha1-adrenergic receptor activity
GO	alpha1-adrenergic receptor activity [Amigo]  alpha1-adrenergic receptor activity
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	apoptosis [Amigo]  apoptosis
GO	smooth muscle contraction [Amigo]  smooth muscle contraction
GO	signal transduction [Amigo]  signal transduction
GO	G-protein coupled receptor protein signaling pathway [Amigo]  G-protein coupled receptor protein signaling pathway
GO	protein kinase cascade [Amigo]  protein kinase cascade
GO	cell-cell signaling [Amigo]  cell-cell signaling
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
KEGG	Calcium signaling pathway
KEGG	Neuroactive ligand-receptor interaction
PubGene	ADRA1A
TreeFam	ADRA1A
CTD	148 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ADRA1A Related clones (RZPD - Berlin)
	PubMed
PubMed	53 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:29:37 2008