ADRBK2 (adrenergic, beta, receptor kinase 2)

Identity

Other names	BARK2
	GRK3
HGNC	ADRBK2
Location	22q11
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ADRBK2   290
Entrez_Gene	ADRBK2  157  adrenergic, beta, receptor kinase 2
	Cards
GeneCards	ADRBK2
Ensembl	ADRBK2 [Search_View]   ENSG00000100077 [Gene_View]
Genatlas	ADRBK2
GeneLynx	ADRBK2
eGenome	ADRBK2
euGene	157
	Genomic and cartography
GoldenPath	ADRBK2  -  22q11   chr22:24290861-24455258 +  22q11.23   [Description]    (hg18-March_2006)
Ensembl	ADRBK2 - 22q11.23 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ADRBK2
	Gene and transcription
Genbank	AK055687 [ ENTREZ ]
Genbank	AK058103 [ ENTREZ ]
Genbank	AK123767 [ ENTREZ ]
Genbank	AK124922 [ ENTREZ ]
Genbank	AK292234 [ ENTREZ ]
RefSeq	NM_005160 [ SRS ]    NM_005160 [ ENTREZ ]
RefSeq	AC_000065 [ SRS ]    AC_000065 [ ENTREZ ]
RefSeq	AC_000154 [ SRS ]    AC_000154 [ ENTREZ ]
RefSeq	NC_000022 [ SRS ]    NC_000022 [ ENTREZ ]
RefSeq	NT_011520 [ SRS ]    NT_011520 [ ENTREZ ]
RefSeq	NW_001838745 [ SRS ]    NW_001838745 [ ENTREZ ]
RefSeq	NW_927628 [ SRS ]    NW_927628 [ ENTREZ ]
AceView	ADRBK2 AceView - NCBI
Unigene	Hs.657494 [ SRS ]    Hs.657494 [ NCBI ]     HS657494 [ spliceNest ]
Fast-db	2988 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P35626 [ SRS]    P35626 [ EXPASY ]     P35626 [ INTERPRO ]     P35626 [ UNIPROT ]
Prosite	PS51285 AGC_KINASE_CTER [ SRS ]    PS51285 AGC_KINASE_CTER [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Prosite	PS50132 RGS [ SRS ]    PS50132 RGS [ Expasy ]
Interpro	IPR015743 BARK [ SRS ]    IPR015743 BARK [ EBI ]
Interpro	IPR000239 GPCR_kinase [ SRS ]    IPR000239 GPCR_kinase [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR000961 Pkinase_C [ SRS ]    IPR000961 Pkinase_C [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR000342 Regulat_G_prot_signal [ SRS ]    IPR000342 Regulat_G_prot_signal [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	P35626
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Pfam	PF00615 RGS [ SRS ]    PF00615 RGS [ Sanger ]    pfam00615 [ NCBI-CDD ]
Smart	SM00233 PH [EMBL]
Smart	SM00315 RGS [EMBL]
Smart	SM00133 S_TK_X [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P35626 ARBK2_HUMAN [ Domain structure ]   P35626 ARBK2_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P35626
HPRD	00183
	Protein Interaction databases
DIP	P35626
IntAct	P35626
	Polymorphism : SNP, mutations, diseases
OMIM	109636    [ map ]
GENECLINICS	109636
SNP	ADRBK2 [dbSNP-NCBI]
SNP	NM_005160 [SNP-NCI]
SNP	ADRBK2 [GeneSNPs - Utah]  ADRBK2] [HGBASE - SRS]
HAPMAP	ADRBK2 [HAPMAP]
COSMIC	ADRBK2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ADRBK2
	General knowledge
Family Browser	ADRBK2 [UCSC Family Browser]
SOURCE	NM_005160
SMD	Hs.657494
SAGE	Hs.657494
Enzyme	2.7.11.15 [ Enzyme-Expasy ]   2.7.11.15 [ Enzyme-SRS ]   2.7.11.15 [ IntEnz-EBI ]   2.7.11.15 [ BRENDA ]   2.7.11.15 [ KEGG ]   2.7.11.15 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	G-protein coupled receptor kinase activity [Amigo]  G-protein coupled receptor kinase activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	ATP binding [Amigo]  ATP binding
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	signal transduction [Amigo]  signal transduction
GO	transferase activity [Amigo]  transferase activity
GO	beta-adrenergic receptor kinase activity [Amigo]  beta-adrenergic receptor kinase activity
KEGG	Olfactory transduction
PubGene	ADRBK2
TreeFam	ADRBK2
CTD	157 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ADRBK2 Related clones (RZPD - Berlin)
	PubMed
PubMed	24 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 19:59:19 2008