AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3)

Identity

Other names	AIFL
	FLJ30473
HGNC	AIFM3
Location	22q11.21
Location_base_pair	Starts at 19649451 and ends at 19665647 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	AIFM3   26398
Entrez_Gene	AIFM3  150209  apoptosis-inducing factor, mitochondrion-associated, 3
	Cards
GeneCards	AIFM3
Ensembl	AIFM3 [Search_View]   ENSG00000183773 [Gene_View]
Genatlas	AIFM3
GeneLynx	AIFM3
eGenome	AIFM3
euGene	150209
	Genomic and cartography
GoldenPath	AIFM3  -  22q11.21   chr22:19649451-19665647 +  22q11.21   [Description]    (hg18-March_2006)
Ensembl	AIFM3 - 22q11.21 [CytoView]
NCBI	Mapview
HomoloGene	AIFM3
	Gene and transcription
Genbank	AK055035 [ ENTREZ ]
Genbank	AK094844 [ ENTREZ ]
Genbank	AK126917 [ ENTREZ ]
Genbank	BC032485 [ ENTREZ ]
Genbank	CR456342 [ ENTREZ ]
RefSeq	NM_001018060 [ SRS ]    NM_001018060 [ ENTREZ ]
RefSeq	NM_144704 [ SRS ]    NM_144704 [ ENTREZ ]
RefSeq	AC_000065 [ SRS ]    AC_000065 [ ENTREZ ]
RefSeq	AC_000154 [ SRS ]    AC_000154 [ ENTREZ ]
RefSeq	NC_000022 [ SRS ]    NC_000022 [ ENTREZ ]
RefSeq	NT_011520 [ SRS ]    NT_011520 [ ENTREZ ]
RefSeq	NW_001838740 [ SRS ]    NW_001838740 [ ENTREZ ]
RefSeq	NW_927495 [ SRS ]    NW_927495 [ ENTREZ ]
AceView	AIFM3 AceView - NCBI
Unigene	Hs.163543 [ SRS ]    Hs.163543 [ NCBI ]     HS163543 [ spliceNest ]
Fast-db	1942 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q96NN9 [ SRS]    Q96NN9 [ EXPASY ]     Q96NN9 [ INTERPRO ]     Q96NN9 [ UNIPROT ]
Prosite	PS51296 RIESKE [ SRS ]    PS51296 RIESKE [ Expasy ]
Interpro	IPR000759 Adrndx_reductase [ SRS ]    IPR000759 Adrndx_reductase [ EBI ]
Interpro	IPR013027 FAD_pyr_nucl-diS_OxRdtase [ SRS ]    IPR013027 FAD_pyr_nucl-diS_OxRdtase [ EBI ]
Interpro	IPR004099 Pyr_nucl-diS_OxRdtase_dimer [ SRS ]    IPR004099 Pyr_nucl-diS_OxRdtase_dimer [ EBI ]
Interpro	IPR001327 Pyr_OxRdtase_NAD_bd [ SRS ]    IPR001327 Pyr_OxRdtase_NAD_bd [ EBI ]
Interpro	IPR000103 Pyridine_nuc-diS_OxRdtase_2 [ SRS ]    IPR000103 Pyridine_nuc-diS_OxRdtase_2 [ EBI ]
Interpro	IPR005805 Rieske_C [ SRS ]    IPR005805 Rieske_C [ EBI ]
Interpro	IPR005806 Rieske_reg [ SRS ]    IPR005806 Rieske_reg [ EBI ]
CluSTr	Q96NN9
Pfam	PF00070 Pyr_redox [ SRS ]    PF00070 Pyr_redox [ Sanger ]    pfam00070 [ NCBI-CDD ]
Pfam	PF07992 Pyr_redox_2 [ SRS ]    PF07992 Pyr_redox_2 [ Sanger ]    pfam07992 [ NCBI-CDD ]
Pfam	PF00355 Rieske [ SRS ]    PF00355 Rieske [ Sanger ]    pfam00355 [ NCBI-CDD ]
Prodom	PD000139 FAD_pyr_redox[INRA-Toulouse]
Prodom	Q96NN9 AIFM3_HUMAN [ Domain structure ]   Q96NN9 AIFM3_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q96NN9
HPRD	08085
	Protein Interaction databases
DIP	Q96NN9
IntAct	Q96NN9
	Polymorphism : SNP, mutations, diseases
SNP	AIFM3 [dbSNP-NCBI]
SNP	NM_001018060 [SNP-NCI]
SNP	NM_144704 [SNP-NCI]
SNP	AIFM3 [GeneSNPs - Utah]  AIFM3] [HGBASE - SRS]
HAPMAP	AIFM3 [HAPMAP]
HGMD	AIFM3
	General knowledge
Family Browser	AIFM3 [UCSC Family Browser]
SOURCE	NM_001018060
SOURCE	NM_144704
SMD	Hs.163543
SAGE	Hs.163543
Enzyme	1.-.-.- [ Enzyme-Expasy ]   1.-.-.- [ Enzyme-SRS ]   1.-.-.- [ IntEnz-EBI ]   1.-.-.- [ BRENDA ]   1.-.-.- [ KEGG ]   1.-.-.- [ WIT ]
GO	iron ion binding [Amigo]  iron ion binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	mitochondrion [Amigo]  mitochondrion
GO	mitochondrial inner membrane [Amigo]  mitochondrial inner membrane
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	cytosol [Amigo]  cytosol
GO	plasma membrane [Amigo]  plasma membrane
GO	transport [Amigo]  transport
GO	apoptosis [Amigo]  apoptosis
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	caspase activation via cytochrome c [Amigo]  caspase activation via cytochrome c
GO	caspase activator activity [Amigo]  caspase activator activity
GO	electron carrier activity [Amigo]  electron carrier activity
GO	oxidoreductase activity [Amigo]  oxidoreductase activity
GO	cell redox homeostasis [Amigo]  cell redox homeostasis
GO	metal ion binding [Amigo]  metal ion binding
GO	FAD binding [Amigo]  FAD binding
GO	2 iron, 2 sulfur cluster binding [Amigo]  2 iron, 2 sulfur cluster binding
GO	mitochondrial depolarization [Amigo]  mitochondrial depolarization
GO	oxidation reduction [Amigo]  oxidation reduction
PubGene	AIFM3
TreeFam	AIFM3
CTD	150209 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	AIFM3 Related clones (RZPD - Berlin)
	PubMed
PubMed	6 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:02:26 2008