AKAP13 (A kinase (PRKA) anchor protein 13)

Identity

Other names	AKAP-Lbc
	BRX
	FLJ11952
	FLJ43341
	HA-3
	Ht31
	LBC
	PROTO-LB
	PROTO-LBC
	c-lbc
Hugo	AKAP13
Location	15q24-q25
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	AKAP13
GDB	AKAP13
Entrez_Gene	AKAP13  11214  A kinase (PRKA) anchor protein 13
	Cards
GeneCards	AKAP13
Ensembl	AKAP13 [Search_View]   ENSG00000170776 [Gene_View]
Genatlas	AKAP13
GeneLynx	AKAP13
eGenome	AKAP13
euGene	11214
	Genomic and cartography
GoldenPath	AKAP13  -     chr15:83724875-84093590 +  15q25.3    (hg18-March_2006)
Ensembl	AKAP13 - 15q25.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	AKAP13
	Gene and transcription
Genbank	AB055890 [ ENTREZ ]
Genbank	AB209414 [ ENTREZ ]
Genbank	AF086293 [ ENTREZ ]
Genbank	AF126008 [ ENTREZ ]
Genbank	AF387101 [ ENTREZ ]
RefSeq	NM_006738 [ SRS ]    NM_006738 [ ENTREZ ]
RefSeq	NM_007200 [ SRS ]    NM_007200 [ ENTREZ ]
RefSeq	NM_144767 [ SRS ]    NM_144767 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010274 [ SRS ]    NT_010274 [ ENTREZ ]
RefSeq	NW_925940 [ SRS ]    NW_925940 [ ENTREZ ]
AceView	AKAP13 AceView - NCBI
Unigene	Hs.703123 [ SRS ]    Hs.703123 [ NCBI ]     HS703123 [ spliceNest ]
Fast-db	9788 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q12802 [ SRS]    Q12802 [ EXPASY ]     Q12802 [ INTERPRO ]
Prosite	PS00741 DH_1 [ SRS ]    PS00741 DH_1 [ Expasy ]
Prosite	PS50010 DH_2 [ SRS ]    PS50010 DH_2 [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR000219 DH-domain [ SRS ]    IPR000219 DH-domain [ EBI ]
Interpro	IPR001331 GDS_CDC24_CS [ SRS ]    IPR001331 GDS_CDC24_CS [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR015721 RhoGEF_like [ SRS ]    IPR015721 RhoGEF_like [ EBI ]
CluSTr	Q12802
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00621 RhoGEF [ SRS ]    PF00621 RhoGEF [ Sanger ]    pfam00621 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00233 PH [EMBL]
Smart	SM00325 RhoGEF [EMBL]
Blocks	Q12802
PDB	2DRN [ SRS ]    2DRN [ PdbSum ],   2DRN [ IMB ]   2DRN [ RSDB ]
HPRD	05253
	Protein Interaction databases
DIP	Q12802
IntAct	Q12802
	Polymorphism : SNP, mutations, diseases
OMIM	604686    [ map ]
GENECLINICS	604686
SNP	AKAP13 [dbSNP-NCBI]
SNP	NM_006738 [SNP-NCI]
SNP	NM_007200 [SNP-NCI]
SNP	NM_144767 [SNP-NCI]
SNP	AKAP13 [GeneSNPs - Utah]  AKAP13] [HGBASE - SRS]
HAPMAP	AKAP13 [HAPMAP]
COSMIC	AKAP13 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	AKAP13
	General knowledge
Family Browser	AKAP13 [UCSC Family Browser]
SOURCE	NM_006738
SOURCE	NM_007200
SOURCE	NM_144767
SMD	Hs.703123
SAGE	Hs.703123
GO	cAMP-dependent protein kinase activity [Amigo]  cAMP-dependent protein kinase activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	receptor activity [Amigo]  receptor activity
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	Rho guanyl-nucleotide exchange factor activity [Amigo]  Rho guanyl-nucleotide exchange factor activity
GO	protein binding [Amigo]  protein binding
GO	cellular_component [Amigo]  cellular_component
GO	intracellular [Amigo]  intracellular
GO	membrane fraction [Amigo]  membrane fraction
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	biological_process [Amigo]  biological_process
GO	zinc ion binding [Amigo]  zinc ion binding
GO	membrane [Amigo]  membrane
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	regulation of Rho protein signal transduction [Amigo]  regulation of Rho protein signal transduction
GO	metal ion binding [Amigo]  metal ion binding
BIOCARTA	Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation    [Genes]
PubGene	AKAP13
	Other databases
	Probes
Probe	AKAP13 Related clones (RZPD - Berlin)
	PubMed
PubMed	33 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

BiblioGene - INIST
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Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Apr 17 08:39:46 2008