APEX2 (APEX nuclease (apurinic/apyrimidinic endonuclease) 2)

Identity

Other names	APE2
	APEXL2
	XTH2
Hugo	APEX2
Location	Xp11.21
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	APEX2
GDB	APEX2
Entrez_Gene	APEX2  27301  APEX nuclease (apurinic/apyrimidinic endonuclease) 2
	Cards
GeneCards	APEX2
Ensembl	APEX2 [Search_View]   ENSG00000169188 [Gene_View]
Genatlas	APEX2
GeneLynx	APEX2
eGenome	APEX2
euGene	27301
	Genomic and cartography
GoldenPath	APEX2  -  Xp11.21   chrX:55043505-55050936 +  Xp11.21    (hg18-March_2006)
Ensembl	APEX2 - Xp11.21 [CytoView]
NCBI	Mapview
HomoloGene	APEX2
	Gene and transcription
Genbank	AB021260 [ ENTREZ ]
Genbank	AB049211 [ ENTREZ ]
Genbank	AF119046 [ ENTREZ ]
Genbank	AJ011311 [ ENTREZ ]
Genbank	BC002959 [ ENTREZ ]
RefSeq	NM_014481 [ SRS ]    NM_014481 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_011630 [ SRS ]    NT_011630 [ ENTREZ ]
RefSeq	NW_927709 [ SRS ]    NW_927709 [ ENTREZ ]
AceView	APEX2 AceView - NCBI
Unigene	Hs.659558 [ SRS ]    Hs.659558 [ NCBI ]     HS659558 [ spliceNest ]
Fast-db	9314 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9UBZ4 [ SRS]    Q9UBZ4 [ EXPASY ]     Q9UBZ4 [ INTERPRO ]
Prosite	PS00726 AP_NUCLEASE_F1_1 [ SRS ]    PS00726 AP_NUCLEASE_F1_1 [ Expasy ]
Prosite	PS00727 AP_NUCLEASE_F1_2 [ SRS ]    PS00727 AP_NUCLEASE_F1_2 [ Expasy ]
Prosite	PS00728 AP_NUCLEASE_F1_3 [ SRS ]    PS00728 AP_NUCLEASE_F1_3 [ Expasy ]
Interpro	IPR000097 AP_endonuc_F1 [ SRS ]    IPR000097 AP_endonuc_F1 [ EBI ]
Interpro	IPR005135 Endo/exonuclease/phosphatase [ SRS ]    IPR005135 Endo/exonuclease/phosphatase [ EBI ]
Interpro	IPR004808 exoDNase_III [ SRS ]    IPR004808 exoDNase_III [ EBI ]
Interpro	IPR010666 Znf_GRF [ SRS ]    IPR010666 Znf_GRF [ EBI ]
CluSTr	Q9UBZ4
Pfam	PF03372 Exo_endo_phos [ SRS ]    PF03372 Exo_endo_phos [ Sanger ]    pfam03372 [ NCBI-CDD ]
Pfam	PF06839 zf-GRF [ SRS ]    PF06839 zf-GRF [ Sanger ]    pfam06839 [ NCBI-CDD ]
Blocks	Q9UBZ4
HPRD	06442
	Protein Interaction databases
DIP	Q9UBZ4
IntAct	Q9UBZ4
	Polymorphism : SNP, mutations, diseases
SNP	APEX2 [dbSNP-NCBI]
SNP	NM_014481 [SNP-NCI]
SNP	APEX2 [GeneSNPs - Utah]  APEX2] [HGBASE - SRS]
HAPMAP	APEX2 [HAPMAP]
COSMIC	APEX2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	APEX2
	General knowledge
Family Browser	APEX2 [UCSC Family Browser]
SOURCE	NM_014481
SMD	Hs.659558
SAGE	Hs.659558
Enzyme	4.2.99.18 [ Enzyme-SRS ]   4.2.99.18 [ Brenda-SRS ]   4.2.99.18 [ KEGG ]   4.2.99.18 [ WIT ]
GO	DNA binding [Amigo]  DNA binding
GO	DNA-(apurinic or apyrimidinic site) lyase activity [Amigo]  DNA-(apurinic or apyrimidinic site) lyase activity
GO	endonuclease activity [Amigo]  endonuclease activity
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	mitochondrion [Amigo]  mitochondrion
GO	DNA repair [Amigo]  DNA repair
GO	zinc ion binding [Amigo]  zinc ion binding
GO	lyase activity [Amigo]  lyase activity
PubGene	APEX2
	Other databases
	Probes
Probe	APEX2 Related clones (RZPD - Berlin)
	PubMed
PubMed	7 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

BiblioGene - INIST
Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Apr 17 08:40:26 2008