ARHGEF16 (Rho guanine exchange factor (GEF) 16)

Identity

Other names	GEF16
	NBR
HGNC	ARHGEF16
Location	1p36.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ARHGEF16   15515
Entrez_Gene	ARHGEF16  27237  Rho guanine exchange factor (GEF) 16
	Cards
GeneCards	ARHGEF16
Ensembl	ARHGEF16 [Search_View]   ENSG00000130762 [Gene_View]
Genatlas	ARHGEF16
GeneLynx	ARHGEF16
eGenome	ARHGEF16
euGene	27237
	Genomic and cartography
GoldenPath	ARHGEF16  -  1p36.3   chr1:3361007-3387537 +  1p36.32   [Description]    (hg18-March_2006)
Ensembl	ARHGEF16 - 1p36.32 [CytoView]
NCBI	Mapview
HomoloGene	ARHGEF16
	Gene and transcription
Genbank	AK091910 [ ENTREZ ]
Genbank	AK095984 [ ENTREZ ]
Genbank	AK310408 [ ENTREZ ]
Genbank	BC002681 [ ENTREZ ]
Genbank	BC051838 [ ENTREZ ]
RefSeq	NM_014448 [ SRS ]    NM_014448 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NT_004321 [ SRS ]    NT_004321 [ ENTREZ ]
RefSeq	NW_001838618 [ SRS ]    NW_001838618 [ ENTREZ ]
RefSeq	NW_923572 [ SRS ]    NW_923572 [ ENTREZ ]
AceView	ARHGEF16 AceView - NCBI
Unigene	Hs.87435 [ SRS ]    Hs.87435 [ NCBI ]     HS87435 [ spliceNest ]
Fast-db	1680 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q5VV41 [ SRS]    Q5VV41 [ EXPASY ]     Q5VV41 [ INTERPRO ]     Q5VV41 [ UNIPROT ]
Prosite	PS00741 DH_1 [ SRS ]    PS00741 DH_1 [ Expasy ]
Prosite	PS50010 DH_2 [ SRS ]    PS50010 DH_2 [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR000219 DH-domain [ SRS ]    IPR000219 DH-domain [ EBI ]
Interpro	IPR001331 GDS_CDC24_CS [ SRS ]    IPR001331 GDS_CDC24_CS [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
CluSTr	Q5VV41
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00621 RhoGEF [ SRS ]    PF00621 RhoGEF [ Sanger ]    pfam00621 [ NCBI-CDD ]
Pfam	PF00018 SH3_1 [ SRS ]    PF00018 SH3_1 [ Sanger ]    pfam00018 [ NCBI-CDD ]
Smart	SM00233 PH [EMBL]
Smart	SM00325 RhoGEF [EMBL]
Smart	SM00326 SH3 [EMBL]
Prodom	PD000066 SH3[INRA-Toulouse]
Prodom	Q5VV41 ARHGG_HUMAN [ Domain structure ]   Q5VV41 ARHGG_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q5VV41
PDB	1X6B [ SRS ]    1X6B [ PdbSum ],   1X6B [ IMB ]   1X6B [ RSDB ]
HPRD	12478
	Protein Interaction databases
DIP	Q5VV41
IntAct	Q5VV41
	Polymorphism : SNP, mutations, diseases
SNP	ARHGEF16 [dbSNP-NCBI]
SNP	NM_014448 [SNP-NCI]
SNP	ARHGEF16 [GeneSNPs - Utah]  ARHGEF16] [HGBASE - SRS]
HAPMAP	ARHGEF16 [HAPMAP]
COSMIC	ARHGEF16 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ARHGEF16
	General knowledge
Family Browser	ARHGEF16 [UCSC Family Browser]
SOURCE	NM_014448
SMD	Hs.87435
SAGE	Hs.87435
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	Rho guanyl-nucleotide exchange factor activity [Amigo]  Rho guanyl-nucleotide exchange factor activity
GO	intracellular [Amigo]  intracellular
GO	regulation of Rho protein signal transduction [Amigo]  regulation of Rho protein signal transduction
PubGene	ARHGEF16
TreeFam	ARHGEF16
CTD	27237 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ARHGEF16 Related clones (RZPD - Berlin)
	PubMed
PubMed	6 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:00:52 2008