ARHGEF7 (Rho guanine nucleotide exchange factor (GEF) 7)

Identity

Other names	BETA-PIX
	COOL1
	DKFZp686C12170
	DKFZp761K1021
	KIAA0142
	KIAA0412
	Nbla10314
	P50
	P50BP
	P85
	P85COOL1
	P85SPR
	PAK3
	PIXB
HGNC	ARHGEF7
Location	13q33.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ARHGEF7   15607
Entrez_Gene	ARHGEF7  8874  Rho guanine nucleotide exchange factor (GEF) 7
	Cards
GeneCards	ARHGEF7
Ensembl	ARHGEF7 [Search_View]   ENSG00000102606 [Gene_View]
Genatlas	ARHGEF7
GeneLynx	ARHGEF7
eGenome	ARHGEF7
euGene	8874
	Genomic and cartography
GoldenPath	ARHGEF7  -  13q33.3   chr13:110565625-110745543 +  13q34   [Description]    (hg18-March_2006)
Ensembl	ARHGEF7 - 13q34 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ARHGEF7
	Gene and transcription
Genbank	AA457036 [ ENTREZ ]
Genbank	AB075521 [ ENTREZ ]
Genbank	AB177848 [ ENTREZ ]
Genbank	AB177849 [ ENTREZ ]
Genbank	AJ844629 [ ENTREZ ]
RefSeq	NM_001113511 [ SRS ]    NM_001113511 [ ENTREZ ]
RefSeq	NM_001113512 [ SRS ]    NM_001113512 [ ENTREZ ]
RefSeq	NM_001113513 [ SRS ]    NM_001113513 [ ENTREZ ]
RefSeq	NM_003899 [ SRS ]    NM_003899 [ ENTREZ ]
RefSeq	NM_145735 [ SRS ]    NM_145735 [ ENTREZ ]
RefSeq	AC_000056 [ SRS ]    AC_000056 [ ENTREZ ]
RefSeq	AC_000145 [ SRS ]    AC_000145 [ ENTREZ ]
RefSeq	NC_000013 [ SRS ]    NC_000013 [ ENTREZ ]
RefSeq	NT_009952 [ SRS ]    NT_009952 [ ENTREZ ]
RefSeq	NW_001838084 [ SRS ]    NW_001838084 [ ENTREZ ]
RefSeq	NW_925517 [ SRS ]    NW_925517 [ ENTREZ ]
AceView	ARHGEF7 AceView - NCBI
Unigene	Hs.508738 [ SRS ]    Hs.508738 [ NCBI ]     HS508738 [ spliceNest ]
Fast-db	9191 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q14155 [ SRS]    Q14155 [ EXPASY ]     Q14155 [ INTERPRO ]     Q14155 [ UNIPROT ]
Prosite	PS50021 CH [ SRS ]    PS50021 CH [ Expasy ]
Prosite	PS00741 DH_1 [ SRS ]    PS00741 DH_1 [ Expasy ]
Prosite	PS50010 DH_2 [ SRS ]    PS50010 DH_2 [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR016146 Calponin-homology [ SRS ]    IPR016146 Calponin-homology [ EBI ]
Interpro	IPR001715 Calponin_act_bd [ SRS ]    IPR001715 Calponin_act_bd [ EBI ]
Interpro	IPR000219 DH-domain [ SRS ]    IPR000219 DH-domain [ EBI ]
Interpro	IPR001331 GDS_CDC24_CS [ SRS ]    IPR001331 GDS_CDC24_CS [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
CluSTr	Q14155
Pfam	PF00307 CH [ SRS ]    PF00307 CH [ Sanger ]    pfam00307 [ NCBI-CDD ]
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00621 RhoGEF [ SRS ]    PF00621 RhoGEF [ Sanger ]    pfam00621 [ NCBI-CDD ]
Pfam	PF00018 SH3_1 [ SRS ]    PF00018 SH3_1 [ Sanger ]    pfam00018 [ NCBI-CDD ]
Smart	SM00033 CH [EMBL]
Smart	SM00233 PH [EMBL]
Smart	SM00325 RhoGEF [EMBL]
Smart	SM00326 SH3 [EMBL]
Prodom	PD000066 SH3[INRA-Toulouse]
Prodom	Q14155 ARHG7_HUMAN [ Domain structure ]   Q14155 ARHG7_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q14155
PDB	1BY1 [ SRS ]    1BY1 [ PdbSum ],   1BY1 [ IMB ]   1BY1 [ RSDB ]
PDB	1ZSG [ SRS ]    1ZSG [ PdbSum ],   1ZSG [ IMB ]   1ZSG [ RSDB ]
HPRD	05688
	Protein Interaction databases
DIP	Q14155
IntAct	Q14155
	Polymorphism : SNP, mutations, diseases
OMIM	605477    [ map ]
GENECLINICS	605477
SNP	ARHGEF7 [dbSNP-NCBI]
SNP	NM_001113511 [SNP-NCI]
SNP	NM_001113512 [SNP-NCI]
SNP	NM_001113513 [SNP-NCI]
SNP	NM_003899 [SNP-NCI]
SNP	NM_145735 [SNP-NCI]
SNP	ARHGEF7 [GeneSNPs - Utah]  ARHGEF7] [HGBASE - SRS]
HAPMAP	ARHGEF7 [HAPMAP]
COSMIC	ARHGEF7 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	ARHGEF7
	General knowledge
Family Browser	ARHGEF7 [UCSC Family Browser]
SOURCE	NM_001113511
SOURCE	NM_001113512
SOURCE	NM_001113513
SOURCE	NM_003899
SOURCE	NM_145735
SMD	Hs.508738
SAGE	Hs.508738
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	Rho guanyl-nucleotide exchange factor activity [Amigo]  Rho guanyl-nucleotide exchange factor activity
GO	intracellular [Amigo]  intracellular
GO	cytosol [Amigo]  cytosol
GO	signal transduction [Amigo]  signal transduction
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	regulation of Rho protein signal transduction [Amigo]  regulation of Rho protein signal transduction
KEGG	Regulation of actin cytoskeleton
PubGene	ARHGEF7
TreeFam	ARHGEF7
CTD	8874 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ARHGEF7 Related clones (RZPD - Berlin)
	PubMed
PubMed	43 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:00:55 2008