ASAH1 (N-acylsphingosine amidohydrolase (acid ceramidase) 1)

Identity

Other names	AC
	ASAH
	FLJ21558
	FLJ22079
	PHP
	PHP32
HGNC	ASAH1
Location	8p22
Location_base_pair	Starts at 17958205 and ends at 17986787 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	ASAH1   735
Entrez_Gene	ASAH1  427  N-acylsphingosine amidohydrolase (acid ceramidase) 1
	Cards
GeneCards	ASAH1
Ensembl	ASAH1 [Search_View]   ENSG00000104763 [Gene_View]
Genatlas	ASAH1
GeneLynx	ASAH1
eGenome	ASAH1
euGene	427
	Genomic and cartography
GoldenPath	ASAH1  -  8p22   chr8:17958205-17986787 -  8p22   [Description]    (hg18-March_2006)
Ensembl	ASAH1 - 8p22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ASAH1
	Gene and transcription
Genbank	AK025211 [ ENTREZ ]
Genbank	AK025732 [ ENTREZ ]
Genbank	AK098299 [ ENTREZ ]
Genbank	AK222780 [ ENTREZ ]
Genbank	AK289481 [ ENTREZ ]
RefSeq	NM_001127505 [ SRS ]    NM_001127505 [ ENTREZ ]
RefSeq	NM_004315 [ SRS ]    NM_004315 [ ENTREZ ]
RefSeq	NM_177924 [ SRS ]    NM_177924 [ ENTREZ ]
RefSeq	AC_000051 [ SRS ]    AC_000051 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_030737 [ SRS ]    NT_030737 [ ENTREZ ]
RefSeq	NW_001839126 [ SRS ]    NW_001839126 [ ENTREZ ]
RefSeq	NW_923907 [ SRS ]    NW_923907 [ ENTREZ ]
AceView	ASAH1 AceView - NCBI
Unigene	Hs.633993 [ SRS ]    Hs.633993 [ NCBI ]     HS633993 [ spliceNest ]
	Protein : pattern, domain, 3D structure
SwissProt	Q13510 [ SRS]    Q13510 [ EXPASY ]     Q13510 [ INTERPRO ]     Q13510 [ UNIPROT ]
Interpro	IPR016699 Acid_ceramidase-like [ SRS ]    IPR016699 Acid_ceramidase-like [ EBI ]
Interpro	IPR003199 Chologlycine_hydro [ SRS ]    IPR003199 Chologlycine_hydro [ EBI ]
CluSTr	Q13510
Pfam	PF02275 CBAH [ SRS ]    PF02275 CBAH [ Sanger ]    pfam02275 [ NCBI-CDD ]
Blocks	Q13510
HPRD	01969
	Protein Interaction databases
DIP	Q13510
IntAct	Q13510
	Polymorphism : SNP, mutations, diseases
OMIM	228000    [ map ]
GENECLINICS	228000
SNP	ASAH1 [dbSNP-NCBI]
SNP	NM_001127505 [SNP-NCI]
SNP	NM_004315 [SNP-NCI]
SNP	NM_177924 [SNP-NCI]
SNP	ASAH1 [GeneSNPs - Utah]  ASAH1] [HGBASE - SRS]
HAPMAP	ASAH1 [HAPMAP]
HGMD	ASAH1
	General knowledge
Family Browser	ASAH1 [UCSC Family Browser]
SOURCE	NM_001127505
SOURCE	NM_004315
SOURCE	NM_177924
SMD	Hs.633993
SAGE	Hs.633993
Enzyme	3.5.1.23 [ Enzyme-Expasy ]   3.5.1.23 [ Enzyme-SRS ]   3.5.1.23 [ IntEnz-EBI ]   3.5.1.23 [ BRENDA ]   3.5.1.23 [ KEGG ]   3.5.1.23 [ WIT ]
GO	lysosome [Amigo]  lysosome
GO	ceramide metabolic process [Amigo]  ceramide metabolic process
GO	response to organic substance [Amigo]  response to organic substance
GO	hydrolase activity [Amigo]  hydrolase activity
GO	ceramidase activity [Amigo]  ceramidase activity
GO	carboxylic acid metabolic process [Amigo]  carboxylic acid metabolic process
GO	lung development [Amigo]  lung development
GO	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Amigo]  transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
BIOCARTA	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor    [Genes]
BIOCARTA	Thrombin signaling and protease-activated receptors    [Genes]
BIOCARTA	Roles of §-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling    [Genes]
BIOCARTA	§-arrestins in GPCR Desensitization    [Genes]
BIOCARTA	Regulation of BAD phosphorylation    [Genes]
BIOCARTA	Role of §-arrestins in the activation and targeting of MAP kinases    [Genes]
BIOCARTA	Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway    [Genes]
BIOCARTA	ChREBP regulation by carbohydrates and cAMP    [Genes]
BIOCARTA	Transcription factor CREB and its extracellular signals    [Genes]
BIOCARTA	Regulation of Spermatogenesis by CREM    [Genes]
BIOCARTA	Phospholipids as signalling intermediaries    [Genes]
BIOCARTA	Signaling Pathway from G-Protein Families    [Genes]
BIOCARTA	Activation of cAMP-dependent protein kinase, PKA    [Genes]
BIOCARTA	Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation    [Genes]
BIOCARTA	How Progesterone Initiates the Oocyte Maturation    [Genes]
BIOCARTA	Phospholipase C-epsilon pathway    [Genes]
BIOCARTA	Ion Channels and Their Functional Role in Vascular Endothelium    [Genes]
KEGG	Sphingolipid metabolism
PubGene	ASAH1
TreeFam	ASAH1
CTD	427 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ASAH1 Related clones (RZPD - Berlin)
	PubMed
PubMed	28 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:31:24 2008