BCL10 (B-cell CLL/lymphoma 10)

Identity

Other names	CARMEN
	CIPER
	CLAP
	c-E10
	mE10
HGNC	BCL10
Location	1p22
Location_base_pair	Starts at 85504048 and ends at 85516171 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	BCL10   989
Entrez_Gene	BCL10  8915  B-cell CLL/lymphoma 10
	Cards
GeneCards	BCL10
Ensembl	BCL10 [Search_View]   ENSG00000142867 [Gene_View]
Genatlas	BCL10
GeneLynx	BCL10
eGenome	BCL10
euGene	8915
	Genomic and cartography
GoldenPath	BCL10  -  1p22   chr1:85504048-85516171 -  1p22.3   [Description]    (hg18-March_2006)
Ensembl	BCL10 - 1p22.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	BCL10
	Gene and transcription
Genbank	AF057700 [ ENTREZ ]
Genbank	AF082283 [ ENTREZ ]
Genbank	AF100338 [ ENTREZ ]
Genbank	AF105066 [ ENTREZ ]
Genbank	AF127386 [ ENTREZ ]
RefSeq	NM_003921 [ SRS ]    NM_003921 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NT_032977 [ SRS ]    NT_032977 [ ENTREZ ]
RefSeq	NW_001838589 [ SRS ]    NW_001838589 [ ENTREZ ]
RefSeq	NW_921795 [ SRS ]    NW_921795 [ ENTREZ ]
AceView	BCL10 AceView - NCBI
Unigene	Hs.193516 [ SRS ]    Hs.193516 [ NCBI ]     HS193516 [ spliceNest ]
Fast-db	16702 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O95999 [ SRS]    O95999 [ EXPASY ]     O95999 [ INTERPRO ]     O95999 [ UNIPROT ]
Prosite	PS50209 CARD [ SRS ]    PS50209 CARD [ Expasy ]
Interpro	IPR001315 CARD [ SRS ]    IPR001315 CARD [ EBI ]
Interpro	IPR011029 DEATH_like [ SRS ]    IPR011029 DEATH_like [ EBI ]
CluSTr	O95999
Pfam	PF00619 CARD [ SRS ]    PF00619 CARD [ Sanger ]    pfam00619 [ NCBI-CDD ]
Blocks	O95999
HPRD	04625
	Protein Interaction databases
DIP	O95999
IntAct	O95999
	Polymorphism : SNP, mutations, diseases
OMIM	603517    [ map ]
GENECLINICS	603517
SNP	BCL10 [dbSNP-NCBI]
SNP	NM_003921 [SNP-NCI]
SNP	BCL10 [GeneSNPs - Utah]  BCL10] [HGBASE - SRS]
HAPMAP	BCL10 [HAPMAP]
COSMIC	BCL10 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	BCL10
	General knowledge
Family Browser	BCL10 [UCSC Family Browser]
SOURCE	NM_003921
SMD	Hs.193516
SAGE	Hs.193516
GO	neural tube closure [Amigo]  neural tube closure
GO	toll-like receptor signaling pathway [Amigo]  toll-like receptor signaling pathway
GO	response to molecule of bacterial origin [Amigo]  response to molecule of bacterial origin
GO	adaptive immune response [Amigo]  adaptive immune response
GO	negative regulation of mature B cell apoptosis [Amigo]  negative regulation of mature B cell apoptosis
GO	transcription coactivator activity [Amigo]  transcription coactivator activity
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	lysosome [Amigo]  lysosome
GO	cytosol [Amigo]  cytosol
GO	cytosol [Amigo]  cytosol
GO	cellular defense response [Amigo]  cellular defense response
GO	protein C-terminus binding [Amigo]  protein C-terminus binding
GO	cell death [Amigo]  cell death
GO	response to fungus [Amigo]  response to fungus
GO	immunoglobulin mediated immune response [Amigo]  immunoglobulin mediated immune response
GO	kinase activator activity [Amigo]  kinase activator activity
GO	positive regulation of protein ubiquitination [Amigo]  positive regulation of protein ubiquitination
GO	ubiquitin protein ligase binding [Amigo]  ubiquitin protein ligase binding
GO	CBM complex [Amigo]  CBM complex
GO	positive regulation of mast cell cytokine production [Amigo]  positive regulation of mast cell cytokine production
GO	T cell receptor complex [Amigo]  T cell receptor complex
GO	lymphotoxin A biosynthetic process [Amigo]  lymphotoxin A biosynthetic process
GO	response to chemical stimulus [Amigo]  response to chemical stimulus
GO	interleukin-6 biosynthetic process [Amigo]  interleukin-6 biosynthetic process
GO	positive regulation of phosphorylation [Amigo]  positive regulation of phosphorylation
GO	regulation of apoptosis [Amigo]  regulation of apoptosis
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO	ubiquitin binding [Amigo]  ubiquitin binding
GO	protein kinase B binding [Amigo]  protein kinase B binding
GO	protein self-association [Amigo]  protein self-association
GO	innate immune response [Amigo]  innate immune response
GO	membrane raft [Amigo]  membrane raft
GO	positive regulation of interleukin-8 biosynthetic process [Amigo]  positive regulation of interleukin-8 biosynthetic process
GO	negative regulation of cell cycle [Amigo]  negative regulation of cell cycle
GO	positive regulation of transcription, DNA-dependent [Amigo]  positive regulation of transcription, DNA-dependent
GO	lipopolysaccharide receptor complex [Amigo]  lipopolysaccharide receptor complex
GO	perinuclear region of cytoplasm [Amigo]  perinuclear region of cytoplasm
GO	regulation of T cell receptor signaling pathway [Amigo]  regulation of T cell receptor signaling pathway
GO	positive regulation of T cell activation [Amigo]  positive regulation of T cell activation
GO	NF-kappaB binding [Amigo]  NF-kappaB binding
GO	positive regulation of NF-kappaB transcription factor activity [Amigo]  positive regulation of NF-kappaB transcription factor activity
GO	protein homooligomerization [Amigo]  protein homooligomerization
GO	protein homooligomerization [Amigo]  protein homooligomerization
KEGG	T cell receptor signaling pathway
KEGG	B cell receptor signaling pathway
PubGene	BCL10
TreeFam	BCL10
CTD	8915 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	BCL10 Related clones (RZPD - Berlin)
	PubMed
PubMed	68 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:32:05 2008