BMP6 (bone morphogenetic protein 6)

Identity

Other names	VGR
	VGR1
HGNC	BMP6
Location	6p24-p23
Location_base_pair	Starts at 7672010 and ends at 7826960 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	BMP6   1073
Entrez_Gene	BMP6  654  bone morphogenetic protein 6
	Cards
GeneCards	BMP6
Ensembl	BMP6 [Search_View]   ENSG00000153162 [Gene_View]
Genatlas	BMP6
GeneLynx	BMP6
eGenome	BMP6
euGene	654
	Genomic and cartography
GoldenPath	BMP6  -     chr6:7672010-7826960 +  6p24.3   [Description]    (hg18-March_2006)
Ensembl	BMP6 - 6p24.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	BMP6
	Gene and transcription
Genbank	BC096084 [ ENTREZ ]
Genbank	BC096085 [ ENTREZ ]
Genbank	BC099624 [ ENTREZ ]
Genbank	BC099625 [ ENTREZ ]
Genbank	BC111763 [ ENTREZ ]
RefSeq	NM_001718 [ SRS ]    NM_001718 [ ENTREZ ]
RefSeq	AC_000049 [ SRS ]    AC_000049 [ ENTREZ ]
RefSeq	AC_000138 [ SRS ]    AC_000138 [ ENTREZ ]
RefSeq	NC_000006 [ SRS ]    NC_000006 [ ENTREZ ]
RefSeq	NT_034880 [ SRS ]    NT_034880 [ ENTREZ ]
RefSeq	NW_001838973 [ SRS ]    NW_001838973 [ ENTREZ ]
RefSeq	NW_922984 [ SRS ]    NW_922984 [ ENTREZ ]
AceView	BMP6 AceView - NCBI
Unigene	Hs.285671 [ SRS ]    Hs.285671 [ NCBI ]     HS285671 [ spliceNest ]
Fast-db	2016 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P22004 [ SRS]    P22004 [ EXPASY ]     P22004 [ INTERPRO ]     P22004 [ UNIPROT ]
Prosite	PS00250 TGF_BETA_1 [ SRS ]    PS00250 TGF_BETA_1 [ Expasy ]
Prosite	PS51362 TGF_BETA_2 [ SRS ]    PS51362 TGF_BETA_2 [ Expasy ]
Interpro	IPR001839 TGFb [ SRS ]    IPR001839 TGFb [ EBI ]
Interpro	IPR001111 TGFb_N [ SRS ]    IPR001111 TGFb_N [ EBI ]
Interpro	IPR015615 TGFbeta [ SRS ]    IPR015615 TGFbeta [ EBI ]
CluSTr	P22004
Pfam	PF00019 TGF_beta [ SRS ]    PF00019 TGF_beta [ Sanger ]    pfam00019 [ NCBI-CDD ]
Pfam	PF00688 TGFb_propeptide [ SRS ]    PF00688 TGFb_propeptide [ Sanger ]    pfam00688 [ NCBI-CDD ]
Smart	SM00204 TGFB [EMBL]
Prodom	PD000357 TGFb[INRA-Toulouse]
Prodom	P22004 BMP6_HUMAN [ Domain structure ]   P22004 BMP6_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P22004
PDB	2QCW [ SRS ]    2QCW [ PdbSum ],   2QCW [ IMB ]   2QCW [ RSDB ]
PDB	2R52 [ SRS ]    2R52 [ PdbSum ],   2R52 [ IMB ]   2R52 [ RSDB ]
PDB	2R53 [ SRS ]    2R53 [ PdbSum ],   2R53 [ IMB ]   2R53 [ RSDB ]
HPRD	00211
	Protein Interaction databases
DIP	P22004
IntAct	P22004
	Polymorphism : SNP, mutations, diseases
OMIM	112266    [ map ]
GENECLINICS	112266
SNP	BMP6 [dbSNP-NCBI]
SNP	NM_001718 [SNP-NCI]
SNP	BMP6 [GeneSNPs - Utah]  BMP6] [HGBASE - SRS]
HAPMAP	BMP6 [HAPMAP]
HGMD	BMP6
	General knowledge
Family Browser	BMP6 [UCSC Family Browser]
SOURCE	NM_001718
SMD	Hs.285671
SAGE	Hs.285671
GO	cytokine activity [Amigo]  cytokine activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	inflammatory response [Amigo]  inflammatory response
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	growth factor activity [Amigo]  growth factor activity
GO	positive regulation of bone mineralization [Amigo]  positive regulation of bone mineralization
GO	BMP signaling pathway [Amigo]  BMP signaling pathway
GO	positive regulation of aldosterone biosynthetic process [Amigo]  positive regulation of aldosterone biosynthetic process
GO	growth [Amigo]  growth
GO	positive regulation of osteoblast differentiation [Amigo]  positive regulation of osteoblast differentiation
GO	positive regulation of transcription from RNA polymerase II promoter [Amigo]  positive regulation of transcription from RNA polymerase II promoter
GO	cartilage development [Amigo]  cartilage development
KEGG	Hedgehog signaling pathway
KEGG	TGF-beta signaling pathway
PubGene	BMP6
TreeFam	BMP6
CTD	654 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	BMP6 Related clones (RZPD - Berlin)
	PubMed
PubMed	43 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:32:25 2008