BMP7 (bone morphogenetic protein 7 (osteogenic protein 1))

Identity

Other names	OP-1
Hugo	BMP7
Location	20q13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	BMP7
GDB	BMP7
Entrez_Gene	BMP7  655  bone morphogenetic protein 7 (osteogenic protein 1)
	Cards
GeneCards	BMP7
Ensembl	BMP7 [Search_View]   ENSG00000101144 [Gene_View]
Genatlas	BMP7
GeneLynx	BMP7
eGenome	BMP7
euGene	655
	Genomic and cartography
GoldenPath	BMP7  -  20q13   chr20:55178962-55274708 -  20q13.31   [Description]    (hg18-March_2006)
Ensembl	BMP7 - 20q13.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	BMP7
	Gene and transcription
Genbank	AK094784 [ ENTREZ ]
Genbank	AK291186 [ ENTREZ ]
Genbank	BC004248 [ ENTREZ ]
Genbank	BC008584 [ ENTREZ ]
Genbank	CR610754 [ ENTREZ ]
RefSeq	NM_001719 [ SRS ]    NM_001719 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011362 [ SRS ]    NT_011362 [ ENTREZ ]
RefSeq	NW_927339 [ SRS ]    NW_927339 [ ENTREZ ]
AceView	BMP7 AceView - NCBI
Unigene	Hs.473163 [ SRS ]    Hs.473163 [ NCBI ]     HS473163 [ spliceNest ]
Fast-db	13750 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P18075 [ SRS]    P18075 [ EXPASY ]     P18075 [ INTERPRO ]
Prosite	PS00250 TGF_BETA_1 [ SRS ]    PS00250 TGF_BETA_1 [ Expasy ]
Prosite	PS51362 TGF_BETA_2 [ SRS ]    PS51362 TGF_BETA_2 [ Expasy ]
Interpro	IPR001839 TGFb [ SRS ]    IPR001839 TGFb [ EBI ]
Interpro	IPR001111 TGFb_N [ SRS ]    IPR001111 TGFb_N [ EBI ]
Interpro	IPR015615 TGFbeta [ SRS ]    IPR015615 TGFbeta [ EBI ]
CluSTr	P18075
Pfam	PF00019 TGF_beta [ SRS ]    PF00019 TGF_beta [ Sanger ]    pfam00019 [ NCBI-CDD ]
Pfam	PF00688 TGFb_propeptide [ SRS ]    PF00688 TGFb_propeptide [ Sanger ]    pfam00688 [ NCBI-CDD ]
Smart	SM00204 TGFB [EMBL]
Prodom	PD000357 TGFb[INRA-Toulouse]
Prodom	P18075 BMP7_HUMAN [ Domain structure ]   P18075 BMP7_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P18075
PDB	1BMP [ SRS ]    1BMP [ PdbSum ],   1BMP [ IMB ]   1BMP [ RSDB ]
PDB	1LX5 [ SRS ]    1LX5 [ PdbSum ],   1LX5 [ IMB ]   1LX5 [ RSDB ]
PDB	1LXI [ SRS ]    1LXI [ PdbSum ],   1LXI [ IMB ]   1LXI [ RSDB ]
PDB	1M4U [ SRS ]    1M4U [ PdbSum ],   1M4U [ IMB ]   1M4U [ RSDB ]
HPRD	00212
	Protein Interaction databases
DIP	P18075
IntAct	P18075
	Polymorphism : SNP, mutations, diseases
OMIM	112267    [ map ]
GENECLINICS	112267
SNP	BMP7 [dbSNP-NCBI]
SNP	NM_001719 [SNP-NCI]
SNP	BMP7 [GeneSNPs - Utah]  BMP7] [HGBASE - SRS]
HAPMAP	BMP7 [HAPMAP]
COSMIC	BMP7 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	BMP7
	General knowledge
Family Browser	BMP7 [UCSC Family Browser]
SOURCE	NM_001719
SMD	Hs.473163
SAGE	Hs.473163
GO	ossification [Amigo]  ossification
GO	epithelial to mesenchymal transition [Amigo]  epithelial to mesenchymal transition
GO	cytokine activity [Amigo]  cytokine activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	growth factor activity [Amigo]  growth factor activity
GO	cell differentiation [Amigo]  cell differentiation
GO	growth [Amigo]  growth
GO	negative regulation of cell cycle [Amigo]  negative regulation of cell cycle
GO	positive regulation of transcription [Amigo]  positive regulation of transcription
GO	cartilage development [Amigo]  cartilage development
BIOCARTA	ALK in cardiac myocytes    [Genes]
KEGG	Cytokine-cytokine receptor interaction
KEGG	Hedgehog signaling pathway
KEGG	TGF-beta signaling pathway
PubGene	BMP7
TreeFam	BMP7
CTD	655 [Comparative Genomics Database]
	Other databases
	Probes
Probe	BMP7 Related clones (RZPD - Berlin)
	PubMed
PubMed	66 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 19:57:52 2008