CAMK1 (calcium/calmodulin-dependent protein kinase I)

Identity

Other names	CAMKI
	MGC120317
	MGC120318
HGNC	CAMK1
Location	3p25.3
Location_base_pair	Starts at 9774031 and ends at 9786661 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CAMK1   1459
Entrez_Gene	CAMK1  8536  calcium/calmodulin-dependent protein kinase I
	Cards
GeneCards	CAMK1
Ensembl	CAMK1 [Search_View]   ENSG00000134072 [Gene_View]
Genatlas	CAMK1
GeneLynx	CAMK1
eGenome	CAMK1
euGene	8536
	Genomic and cartography
GoldenPath	CAMK1  -  3p25.3   chr3:9774031-9786661 -  3p25.3   [Description]    (hg18-March_2006)
Ensembl	CAMK1 - 3p25.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CAMK1
	Gene and transcription
Genbank	AK314917 [ ENTREZ ]
Genbank	BC106754 [ ENTREZ ]
Genbank	BC106755 [ ENTREZ ]
Genbank	BI546222 [ ENTREZ ]
Genbank	CR607002 [ ENTREZ ]
RefSeq	NM_003656 [ SRS ]    NM_003656 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838876 [ SRS ]    NW_001838876 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	CAMK1 AceView - NCBI
Unigene	Hs.434875 [ SRS ]    Hs.434875 [ NCBI ]     HS434875 [ spliceNest ]
Fast-db	1452 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q14012 [ SRS]    Q14012 [ EXPASY ]     Q14012 [ INTERPRO ]     Q14012 [ UNIPROT ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR015734 CaMKI [ SRS ]    IPR015734 CaMKI [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q14012
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q14012 KCC1A_HUMAN [ Domain structure ]   Q14012 KCC1A_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q14012
HPRD	05412
	Protein Interaction databases
DIP	Q14012
IntAct	Q14012
	Polymorphism : SNP, mutations, diseases
OMIM	604998    [ map ]
GENECLINICS	604998
SNP	CAMK1 [dbSNP-NCBI]
SNP	NM_003656 [SNP-NCI]
SNP	CAMK1 [GeneSNPs - Utah]  CAMK1] [HGBASE - SRS]
HAPMAP	CAMK1 [HAPMAP]
COSMIC	CAMK1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CAMK1
	General knowledge
Family Browser	CAMK1 [UCSC Family Browser]
SOURCE	NM_003656
SMD	Hs.434875
SAGE	Hs.434875
Enzyme	2.7.11.17 [ Enzyme-Expasy ]   2.7.11.17 [ Enzyme-SRS ]   2.7.11.17 [ IntEnz-EBI ]   2.7.11.17 [ BRENDA ]   2.7.11.17 [ KEGG ]   2.7.11.17 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	calmodulin-dependent protein kinase activity [Amigo]  calmodulin-dependent protein kinase activity
GO	calmodulin binding [Amigo]  calmodulin binding
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	nucleocytoplasmic transport [Amigo]  nucleocytoplasmic transport
GO	signal transduction [Amigo]  signal transduction
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	nervous system development [Amigo]  nervous system development
GO	transferase activity [Amigo]  transferase activity
GO	cell differentiation [Amigo]  cell differentiation
BIOCARTA	Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling    [Genes]
BIOCARTA	Ca++/ Calmodulin-dependent Protein Kinase Activation    [Genes]
BIOCARTA	Pertussis toxin-insensitive CCR5 Signaling in Macrophage    [Genes]
BIOCARTA	Signal Dependent Regulation of Myogenesis by Corepressor MITR    [Genes]
BIOCARTA	BCR Signaling Pathway    [Genes]
BIOCARTA	Bioactive Peptide Induced Signaling Pathway    [Genes]
BIOCARTA	Effects of calcineurin in Keratinocyte Differentiation    [Genes]
BIOCARTA	fMLP induced chemokine gene expression in HMC-1 cells    [Genes]
BIOCARTA	Fc Epsilon Receptor I Signaling in Mast Cells    [Genes]
BIOCARTA	Corticosteroids and cardioprotection    [Genes]
BIOCARTA	Signaling Pathway from G-Protein Families    [Genes]
BIOCARTA	Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK)    [Genes]
BIOCARTA	Role of MEF2D in T-cell Apoptosis    [Genes]
BIOCARTA	Endocytotic role of NDK, Phosphins and Dynamin    [Genes]
BIOCARTA	NFAT and Hypertrophy of the heart (Transcription in the broken heart)    [Genes]
BIOCARTA	Actions of Nitric Oxide in the Heart    [Genes]
BIOCARTA	Nitric Oxide Signaling Pathway    [Genes]
BIOCARTA	Regulation of PGC-1a    [Genes]
BIOCARTA	Links between Pyk2 and Map Kinases    [Genes]
BIOCARTA	T Cell Receptor Signaling Pathway    [Genes]
BIOCARTA	Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells    [Genes]
PubGene	CAMK1
TreeFam	CAMK1
CTD	8536 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CAMK1 Related clones (RZPD - Berlin)
	PubMed
PubMed	30 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:33:21 2008