CAPN6 (calpain 6)

2008-12-01  

Identity

HGNC
LOCATION
Xq23
LOCUSID
ALIAS
CANPX,CAPNX,CalpM,DJ914P14.1
FUSION GENES

Other Information

Locus ID:

NCBI: 827
MIM: 300146
HGNC: 1483
Ensembl: ENSG00000077274

Variants:

dbSNP: 827
ClinVar: 827
TCGA: ENSG00000077274
COSMIC: CAPN6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077274ENST00000324068Q9Y6Q1

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
263754402016miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1.20
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
216817442012Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma.9
186579002008Calpain 6 supports tumorigenesis by inhibiting apoptosis and facilitating angiogenesis.7
275254422016Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.7
204141412010Family-based association study for bipolar affective disorder.0

Citation

Dessen P

CAPN6 (calpain 6)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50536/capn6