CAPN9 (calpain 9)

2003-02-01  

Identity

HGNC
LOCATION
1q42.2
LOCUSID
ALIAS
GC36,nCL-4

Other Information

Locus ID:

NCBI: 10753
MIM: 606401
HGNC: 1486
Ensembl: ENSG00000135773

Variants:

dbSNP: 10753
ClinVar: 10753
TCGA: ENSG00000135773
COSMIC: CAPN9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135773ENST00000271971O14815
ENSG00000135773ENST00000354537O14815
ENSG00000135773ENST00000366666E7ESS6

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
190748852008Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.25
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.23
171573132007The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition.18
255395772014Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer.5
274048912016Decreased expression of Calpain-9 predicts unfavorable prognosis in patients with gastric cancer.5

Citation

Dessen P

CAPN9 (calpain 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/910/capn9