CARD11 (caspase recruitment domain family, member 11)

Identity

Other names	BIMP3
	CARMA1
	MGC133069
HGNC	CARD11
Location	7p22
Location_base_pair	Starts at 2912295 and ends at 3050105 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CARD11   16393
Entrez_Gene	CARD11  84433  caspase recruitment domain family, member 11
	Cards
GeneCards	CARD11
Ensembl	ENSG00000198286 [Gene_View]  CARD11 [Vega]
Genatlas	CARD11
	Genomic and cartography
GoldenPath	CARD11  -  7p22   chr7:2912295-3050105 -  7p22.2   [Description]    (hg18-March_2006)
Ensembl	CARD11 - 7p22.2 [CytoView]
NCBI	Mapview
OMIM	607210 Disease map [OMIM]
HomoloGene	CARD11
	Gene and transcription
Genbank	AA194010 [ ENTREZ ]
Genbank	AF322641 [ ENTREZ ]
Genbank	AF352576 [ ENTREZ ]
Genbank	AK074049 [ ENTREZ ]
Genbank	AK097139 [ ENTREZ ]
RefSeq	NM_032415 [ SRS ]    NM_032415 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001838998 [ SRS ]    NW_001838998 [ ENTREZ ]
RefSeq	NW_923206 [ SRS ]    NW_923206 [ ENTREZ ]
CCDS	CARD11 CCDS - NCBI
AceView	CARD11 AceView - NCBI
Unigene	Hs.665701 [ SRS ]    Hs.665701 [ NCBI ]
Fast-db	1162 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9BXL7 [ SRS]    Q9BXL7 [ EXPASY ]     Q9BXL7 [ INTERPRO ]     Q9BXL7 [ UNIPROT ] Q9BXL7 [ VarSplice FASTA ]
Prosite	PS50209 CARD [ SRS ]    PS50209 CARD [ Expasy ]
Prosite	PS00856 GUANYLATE_KINASE_1 [ SRS ]    PS00856 GUANYLATE_KINASE_1 [ Expasy ]
Prosite	PS50052 GUANYLATE_KINASE_2 [ SRS ]    PS50052 GUANYLATE_KINASE_2 [ Expasy ]
Prosite	PS50106 PDZ [ SRS ]    PS50106 PDZ [ Expasy ]
Interpro	IPR001315 CARD [ SRS ]    IPR001315 CARD [ EBI ]
Interpro	IPR008144 Guanylate_kin [ SRS ]    IPR008144 Guanylate_kin [ EBI ]
Interpro	IPR001478 PDZ [ SRS ]    IPR001478 PDZ [ EBI ]
CluSTr	Q9BXL7
Pfam	PF00619 CARD [ SRS ]    PF00619 CARD [ Sanger ]    pfam00619 [ NCBI-CDD ]
Smart	SM00228 PDZ [EMBL]
Blocks	Q9BXL7
HPRD	06234
	Protein Interaction databases
DIP	Q9BXL7
IntAct	Q9BXL7
	Polymorphism : SNP, mutations, diseases
OMIM	607210    [ map ]
GENETests	607210
SNP	CARD11 [dbSNP-NCBI]
SNP	NM_032415 [SNP-NCI]
SNP	CARD11 [GeneSNPs - Utah]  CARD11] [HGBASE - SRS]
HAPMAP	CARD11 [HAPMAP]
COSMIC	CARD11 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CARD11
Genetic Association	CARD11
CDC HuGE	CARD11
	General knowledge
Family Browser	CARD11 [UCSC Family Browser]
SOURCE	NM_032415
SMD	Hs.665701
SAGE	Hs.665701
GO	positive regulation of cytokine production [Amigo]  positive regulation of cytokine production
GO	guanylate kinase activity [Amigo]  guanylate kinase activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	plasma membrane [Amigo]  plasma membrane
GO	signal transduction [Amigo]  signal transduction
GO	positive regulation of B cell proliferation [Amigo]  positive regulation of B cell proliferation
GO	T cell receptor complex [Amigo]  T cell receptor complex
GO	positive regulation of T cell proliferation [Amigo]  positive regulation of T cell proliferation
GO	regulation of apoptosis [Amigo]  regulation of apoptosis
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO	thymic T cell selection [Amigo]  thymic T cell selection
GO	positive regulation of interleukin-2 biosynthetic process [Amigo]  positive regulation of interleukin-2 biosynthetic process
GO	membrane raft [Amigo]  membrane raft
GO	regulation of B cell differentiation [Amigo]  regulation of B cell differentiation
GO	regulation of T cell differentiation [Amigo]  regulation of T cell differentiation
GO	CARD domain binding [Amigo]  CARD domain binding
GO	regulation of immune response [Amigo]  regulation of immune response
GO	positive regulation of NF-kappaB transcription factor activity [Amigo]  positive regulation of NF-kappaB transcription factor activity
KEGG	T cell receptor signaling pathway
KEGG	B cell receptor signaling pathway
PubGene	CARD11
TreeFam	CARD11
CTD	84433 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CARD11 Related clones (RZPD - Berlin)
	PubMed
PubMed	29 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Dec 6 16:37:33 2008