CASP10 (caspase 10, apoptosis-related cysteine peptidase)

Identity

Other names	ALPS2
	FLICE2
	MCH4
HGNC	CASP10
Location	2q33-q34
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CASP10   1500
Entrez_Gene	CASP10  843  caspase 10, apoptosis-related cysteine peptidase
	Cards
GeneCards	CASP10
Ensembl	CASP10 [Search_View]   ENSG00000003400 [Gene_View]
Genatlas	CASP10
GeneLynx	CASP10
eGenome	CASP10
euGene	843
	Genomic and cartography
GoldenPath	CASP10  -     chr2:201755866-201794628 +  2q33.1   [Description]    (hg18-March_2006)
Ensembl	CASP10 - 2q33.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CASP10
	Gene and transcription
Genbank	AF111344 [ ENTREZ ]
Genbank	AF111345 [ ENTREZ ]
Genbank	AI696103 [ ENTREZ ]
Genbank	AJ487678 [ ENTREZ ]
Genbank	AJ487679 [ ENTREZ ]
RefSeq	NM_001230 [ SRS ]    NM_001230 [ ENTREZ ]
RefSeq	NM_032974 [ SRS ]    NM_032974 [ ENTREZ ]
RefSeq	NM_032977 [ SRS ]    NM_032977 [ ENTREZ ]
RefSeq	AC_000045 [ SRS ]    AC_000045 [ ENTREZ ]
RefSeq	AC_000134 [ SRS ]    AC_000134 [ ENTREZ ]
RefSeq	NC_000002 [ SRS ]    NC_000002 [ ENTREZ ]
RefSeq	NG_007265 [ SRS ]    NG_007265 [ ENTREZ ]
RefSeq	NG_007497 [ SRS ]    NG_007497 [ ENTREZ ]
RefSeq	NT_005403 [ SRS ]    NT_005403 [ ENTREZ ]
RefSeq	NW_001838863 [ SRS ]    NW_001838863 [ ENTREZ ]
RefSeq	NW_921618 [ SRS ]    NW_921618 [ ENTREZ ]
AceView	CASP10 AceView - NCBI
Unigene	Hs.5353 [ SRS ]    Hs.5353 [ NCBI ]     HS5353 [ spliceNest ]
Fast-db	14314 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q68HC0 [ SRS]    Q68HC0 [ EXPASY ]     Q68HC0 [ INTERPRO ]     Q68HC0 [ UNIPROT ]
Prosite	PS50168 DED [ SRS ]    PS50168 DED [ Expasy ]
Interpro	IPR011029 DEATH_like [ SRS ]    IPR011029 DEATH_like [ EBI ]
Interpro	IPR001875 DED [ SRS ]    IPR001875 DED [ EBI ]
Interpro	IPR002398 Pept_C14_p45 [ SRS ]    IPR002398 Pept_C14_p45 [ EBI ]
CluSTr	Q68HC0
Pfam	PF01335 DED [ SRS ]    PF01335 DED [ Sanger ]    pfam01335 [ NCBI-CDD ]
Smart	SM00031 DED [EMBL]
Blocks	Q68HC0
HPRD	03458
	Protein Interaction databases
DIP	Q68HC0
IntAct	Q68HC0
	Polymorphism : SNP, mutations, diseases
OMIM	137215;601762;603909;605027    [ map ]
GENECLINICS	137215;601762;603909;605027
SNP	CASP10 [dbSNP-NCBI]
SNP	NM_001230 [SNP-NCI]
SNP	NM_032974 [SNP-NCI]
SNP	NM_032977 [SNP-NCI]
SNP	CASP10 [GeneSNPs - Utah]  CASP10] [HGBASE - SRS]
HAPMAP	CASP10 [HAPMAP]
COSMIC	CASP10 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CASP10
	General knowledge
Family Browser	CASP10 [UCSC Family Browser]
SOURCE	NM_001230
SOURCE	NM_032974
SOURCE	NM_032977
SMD	Hs.5353
SAGE	Hs.5353
GO	protein binding [Amigo]  protein binding
GO	proteolysis [Amigo]  proteolysis
GO	cysteine-type peptidase activity [Amigo]  cysteine-type peptidase activity
GO	induction of apoptosis by extracellular signals [Amigo]  induction of apoptosis by extracellular signals
GO	caspase activity [Amigo]  caspase activity
GO	caspase activity [Amigo]  caspase activity
GO	identical protein binding [Amigo]  identical protein binding
GO	regulation of apoptosis [Amigo]  regulation of apoptosis
BIOCARTA	Caspase Cascade in Apoptosis    [Genes]
BIOCARTA	D4-GDI Signaling Pathway    [Genes]
BIOCARTA	Induction of apoptosis through DR3 and DR4/5 Death Receptors    [Genes]
BIOCARTA	FAS signaling pathway ( CD95 )    [Genes]
KEGG	MAPK signaling pathway
KEGG	Apoptosis
PubGene	CASP10
TreeFam	CASP10
CTD	843 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CASP10 Related clones (RZPD - Berlin)
	PubMed
PubMed	59 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:03:13 2008