CCR4 (chemokine (C-C motif) receptor 4)

Identity

Other names	CC-CKR-4
	CD194
	CKR4
	CMKBR4
	ChemR13
	HGCN:14099
	K5-5
	MGC88293
HGNC	CCR4
Location	3p24-p21.3
Location_base_pair	Starts at 32968070 and ends at 32971407 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CCR4   1605
Entrez_Gene	CCR4  1233  chemokine (C-C motif) receptor 4
	Cards
GeneCards	CCR4
Ensembl	CCR4 [Search_View]   ENSG00000183813 [Gene_View]
Genatlas	CCR4
GeneLynx	CCR4
eGenome	CCR4
euGene	1233
	Genomic and cartography
GoldenPath	CCR4  -     chr3:32968070-32971407 +  3p22.3   [Description]    (hg18-March_2006)
Ensembl	CCR4 - 3p22.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CCR4
	Gene and transcription
Genbank	AK292674 [ ENTREZ ]
Genbank	BC069139 [ ENTREZ ]
Genbank	BC071751 [ ENTREZ ]
Genbank	BC074935 [ ENTREZ ]
Genbank	CD639869 [ ENTREZ ]
RefSeq	NM_005508 [ SRS ]    NM_005508 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838877 [ SRS ]    NW_001838877 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	CCR4 AceView - NCBI
Unigene	Hs.184926 [ SRS ]    Hs.184926 [ NCBI ]     HS184926 [ spliceNest ]
Fast-db	3550 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P51679 [ SRS]    P51679 [ EXPASY ]     P51679 [ INTERPRO ]     P51679 [ UNIPROT ]
Prosite	PS00237 G_PROTEIN_RECEP_F1_1 [ SRS ]    PS00237 G_PROTEIN_RECEP_F1_1 [ Expasy ]
Prosite	PS50262 G_PROTEIN_RECEP_F1_2 [ SRS ]    PS50262 G_PROTEIN_RECEP_F1_2 [ Expasy ]
Interpro	IPR000190 ATII_AT1_rcpt [ SRS ]    IPR000190 ATII_AT1_rcpt [ EBI ]
Interpro	IPR002239 CC_4_rcpt [ SRS ]    IPR002239 CC_4_rcpt [ EBI ]
Interpro	IPR000355 Chmkine_rcpt [ SRS ]    IPR000355 Chmkine_rcpt [ EBI ]
Interpro	IPR000276 GPCR_Rhodpsn [ SRS ]    IPR000276 GPCR_Rhodpsn [ EBI ]
Interpro	IPR017452 GPCR_Rhodpsn_supfam [ SRS ]    IPR017452 GPCR_Rhodpsn_supfam [ EBI ]
CluSTr	P51679
Pfam	PF00001 7tm_1 [ SRS ]    PF00001 7tm_1 [ Sanger ]    pfam00001 [ NCBI-CDD ]
Blocks	P51679
HPRD	05324
	Protein Interaction databases
DIP	P51679
IntAct	P51679
	Polymorphism : SNP, mutations, diseases
OMIM	604836    [ map ]
GENECLINICS	604836
SNP	CCR4 [dbSNP-NCBI]
SNP	NM_005508 [SNP-NCI]
SNP	CCR4 [GeneSNPs - Utah]  CCR4] [HGBASE - SRS]
HAPMAP	CCR4 [HAPMAP]
COSMIC	CCR4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CCR4
	General knowledge
Family Browser	CCR4 [UCSC Family Browser]
SOURCE	NM_005508
SMD	Hs.184926
SAGE	Hs.184926
GO	rhodopsin-like receptor activity [Amigo]  rhodopsin-like receptor activity
GO	neuron migration [Amigo]  neuron migration
GO	tolerance induction [Amigo]  tolerance induction
GO	receptor activity [Amigo]  receptor activity
GO	angiotensin type II receptor activity [Amigo]  angiotensin type II receptor activity
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	chemotaxis [Amigo]  chemotaxis
GO	inflammatory response [Amigo]  inflammatory response
GO	immune response [Amigo]  immune response
GO	signal transduction [Amigo]  signal transduction
GO	G-protein coupled receptor protein signaling pathway [Amigo]  G-protein coupled receptor protein signaling pathway
GO	elevation of cytosolic calcium ion concentration [Amigo]  elevation of cytosolic calcium ion concentration
GO	C-C chemokine receptor activity [Amigo]  C-C chemokine receptor activity
BIOCARTA	Selective expression of chemokine receptors during T-cell polarization    [Genes]
KEGG	Cytokine-cytokine receptor interaction
PubGene	CCR4
TreeFam	CCR4
CTD	1233 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CCR4 Related clones (RZPD - Berlin)
	PubMed
PubMed	35 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:34:05 2008