CD274 (CD274 molecule)

Identity

Other names	B7-H
	B7H1
	MGC142294
	MGC142296
	PD-L1
	PDCD1L1
	PDCD1LG1
	PDL1
HGNC	CD274
Location	9p24.1
Location_base_pair	Starts at 5440559 and ends at 5458477 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CD274   17635
Entrez_Gene	CD274  29126  CD274 molecule
	Cards
GeneCards	CD274
Ensembl	CD274 [Search_View]   ENSG00000120217 [Gene_View]
Genatlas	CD274
GeneLynx	CD274
eGenome	CD274
euGene	29126
	Genomic and cartography
GoldenPath	CD274  -  9p24.1   chr9:5440559-5458477 +  9p24.1   [Description]    (hg18-March_2006)
Ensembl	CD274 - 9p24.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CD274
	Gene and transcription
Genbank	AF177937 [ ENTREZ ]
Genbank	AF233516 [ ENTREZ ]
Genbank	AK001894 [ ENTREZ ]
Genbank	AK314567 [ ENTREZ ]
Genbank	AY254342 [ ENTREZ ]
RefSeq	NM_014143 [ SRS ]    NM_014143 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	CD274 AceView - NCBI
Unigene	Hs.521989 [ SRS ]    Hs.521989 [ NCBI ]     HS521989 [ spliceNest ]
Fast-db	1806 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q0GN75 [ SRS]    Q0GN75 [ EXPASY ]     Q0GN75 [ INTERPRO ]     Q0GN75 [ UNIPROT ]
Prosite	PS50835 IG_LIKE [ SRS ]    PS50835 IG_LIKE [ Expasy ]
Interpro	IPR007110 Ig-like [ SRS ]    IPR007110 Ig-like [ EBI ]
Interpro	IPR013783 Ig-like_fold [ SRS ]    IPR013783 Ig-like_fold [ EBI ]
Interpro	IPR003599 Ig_sub [ SRS ]    IPR003599 Ig_sub [ EBI ]
CluSTr	Q0GN75
Smart	SM00409 IG [EMBL]
Blocks	Q0GN75
HPRD	05655
	Protein Interaction databases
DIP	Q0GN75
IntAct	Q0GN75
	Polymorphism : SNP, mutations, diseases
OMIM	605402    [ map ]
GENECLINICS	605402
SNP	CD274 [dbSNP-NCBI]
SNP	NM_014143 [SNP-NCI]
SNP	CD274 [GeneSNPs - Utah]  CD274] [HGBASE - SRS]
HAPMAP	CD274 [HAPMAP]
COSMIC	CD274 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CD274
	General knowledge
Family Browser	CD274 [UCSC Family Browser]
SOURCE	NM_014143
SMD	Hs.521989
SAGE	Hs.521989
GO	receptor activity [Amigo]  receptor activity
GO	protein binding [Amigo]  protein binding
GO	plasma membrane [Amigo]  plasma membrane
GO	immune response [Amigo]  immune response
GO	cell surface receptor linked signal transduction [Amigo]  cell surface receptor linked signal transduction
GO	cell proliferation [Amigo]  cell proliferation
GO	external side of plasma membrane [Amigo]  external side of plasma membrane
GO	endomembrane system [Amigo]  endomembrane system
GO	integral to membrane [Amigo]  integral to membrane
GO	negative regulation of T cell proliferation [Amigo]  negative regulation of T cell proliferation
KEGG	Cell adhesion molecules (CAMs)
PubGene	CD274
TreeFam	CD274
CTD	29126 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CD274 Related clones (RZPD - Berlin)
	PubMed
PubMed	58 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:34:17 2008