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CDH2 (cadherin 2, type 1, N-cadherin (neuronal))

Identity

Other namesCD325
CDHN
CDw325
NCAD
HGNC (Hugo) CDH2
Location 18q12.1
Location_base_pair Starts at 23784928 and ends at 24011443 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CDH2   1759
Entrez_Gene (NCBI)CDH2  1000  cadherin 2, type 1, N-cadherin (neuronal)
Cards
GeneCards (Weizmann)CDH2
Ensembl (Hinxton)ENSG00000170558 [Gene_View]  CDH2 [Vega]
AceView (NCBI)CDH2
Genatlas (Paris)CDH2
euGene (Indiana)1000
SOURCE (Stanford)NM_001792
Gene Expression (Array Express) ENSG00000170558
Genomic and cartography
GoldenPath (UCSC)CDH2  -  18q12.1   chr18:23784928-24011443 -  18q12.1   [Description]    (hg18-March_2006)
EnsemblCDH2 - 18q12.1 [CytoView]
Mapping of homologs : NCBICDH2 [Mapview]
OMIM114020   
Gene and transcription
Gene : Genbank (Entrez)AA661623 AI675151 AI752179 AI752180 AK302831
Reference sequence (RefSeq transcript) :SRSNM_001792
Reference transcript : EntrezNM_001792
RefSeq genomic : SRSAC_000061 AC_000150 NC_000018 NG_011959 NT_010966 NW_001838467 NW_927095
RefSeq genomic : EntrezAC_000061 AC_000150 NC_000018 NG_011959 NT_010966 NW_001838467 NW_927095
Consensus coding sequences : CCDS NCBICDH2
Cluster EST : UnigeneHs.606106 [ SRS ] Hs.606106 [ NCBI ]
Alternative Splicing : Fast-db (Paris)2907
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtP19022 (SRS) P19022 (Expasy) P19022 (Uniprot)
With graphics : InterProP19022
Splice isoforms : VarSplice FASTAP19022(VarSplice FASTA)
Domaine pattern : Prosite (SRS)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domain pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (SRS)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Cadherin_pro    Desmocollin   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Cadherin_pro    Desmocollin   
Related proteins : CluSTrP19022
Domain families : Pfam SRSCadherin (PF00028)    Cadherin_C (PF01049)    Cadherin_pro (PF08758)   
Domain families : Pfam SangerCadherin (PF00028)    Cadherin_C (PF01049)    Cadherin_pro (PF08758)   
Domain families : Pfam NCBIpfam00028    pfam01049    pfam08758   
Domain families : Smart EMBLCA (SM00112)  
Blocks (Seattle)P19022
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD00226
Protein Interaction databases
DIP (DOE-UCLA)P19022
IntAct (EBI)P19022
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBICDH2
SNP : GeneSNP UtahCDH2
SNP : HGBaseCDH2
Genetic variants : HAPMAPCDH2
Somatic Mutations in Cancer : COSMICCDH2 
Mutations and Diseases : HGMDCDH2
Hereditary diseases : OMIM114020   
Hereditary diseases : GENETests114020   
Diseases : Genetic AssociationCDH2
General knowledge
Homologs : HomoloGeneCDH2
Homology/Alignments : Family Browser UCSCCDH2
Phylogenetic Trees/Animal Genes : TreeFamCDH2
Chemical/Protein Interactions : CTD1000
Keywords Ontology : AmiGOcalcium ion binding  plasma membrane  adherens junction  fascia adherens  cell adhesion  homophilic cell adhesion  heterophilic cell adhesion  synapse assembly  beta-catenin binding  integral to membrane  calcium-dependent cell-cell adhesion  cell migration  protein kinase binding  protein phosphatase binding  lamellipodium  regulation of myelination  regulation of protein localization  regulation of Rho protein signal transduction  RPTP-like protein binding  protein complex  synapse  blood vessel morphogenesis  regulation of axonogenesis  protein heterooligomerization  
Keywords Ontology : EGO-EBIcalcium ion binding  plasma membrane  adherens junction  fascia adherens  cell adhesion  homophilic cell adhesion  heterophilic cell adhesion  synapse assembly  beta-catenin binding  integral to membrane  calcium-dependent cell-cell adhesion  cell migration  protein kinase binding  protein phosphatase binding  lamellipodium  regulation of myelination  regulation of protein localization  regulation of Rho protein signal transduction  RPTP-like protein binding  protein complex  synapse  blood vessel morphogenesis  regulation of axonogenesis  protein heterooligomerization  
Pathways : BIOCARTA
Pathways : KEGGCell adhesion molecules (CAMs)
Other databases
Probes
Probes : ImagenesCDH2 Related clones (RZPD - Berlin)
Literature
PubMed113 Pubmed reference(s) in Entrez
PubGeneCDH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:38:59 CET 2010
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