Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2))

Identity

Other namesBWCR
BWS
KIP2
WBS
p57
HGNC (Hugo) CDKN1C
Location 11p15.4
Location_base_pair Starts at 2861024 and ends at 2863571 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CDKN1C   1786
Entrez_Gene (NCBI)CDKN1C  1028  cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Cards
GeneCards (Weizmann)CDKN1C
Ensembl (Hinxton)ENSG00000129757 [Gene_View]  CDKN1C [Vega]
AceView (NCBI)CDKN1C
Genatlas (Paris)CDKN1C
euGene (Indiana)1028
SOURCE (Stanford)NM_000076 NM_001122630 NM_001122631
Gene Expression (Array Express) ENSG00000129757
Genomic and cartography
GoldenPath (UCSC)CDKN1C  -  11p15.4   chr11:2861024-2863571 -  11p15.4   [Description]    (hg18-March_2006)
EnsemblCDKN1C - 11p15.4 [CytoView]
Mapping of homologs : NCBICDKN1C [Mapview]
OMIM130650   600856   
Gene and transcription
Gene : Genbank (Entrez)BC039188 BC067842 BM673714 CD676249 CR591638
Reference sequence (RefSeq transcript) :SRSNM_000076 NM_001122630 NM_001122631
Reference transcript : EntrezNM_000076 NM_001122630 NM_001122631
RefSeq genomic : SRSAC_000054 AC_000143 NC_000011 NG_008022 NT_009237 NW_001838018 NW_924962
RefSeq genomic : EntrezAC_000054 AC_000143 NC_000011 NG_008022 NT_009237 NW_001838018 NW_924962
Consensus coding sequences : CCDS NCBICDKN1C
Cluster EST : UnigeneHs.106070 [ SRS ] Hs.106070 [ NCBI ]
Alternative Splicing : Fast-db (Paris)1034
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtP49918 (SRS) P49918 (Expasy) P49918 (Uniprot)
With graphics : InterProP49918
Splice isoforms : VarSplice FASTAP49918(VarSplice FASTA)
Domains : Interpro (SRS)CDI   
Domains : Interpro (EBI)CDI   
Related proteins : CluSTrP49918
Domain families : Pfam SRSCDI (PF02234)   
Domain families : Pfam SangerCDI (PF02234)   
Domain families : Pfam NCBIpfam02234   
Blocks (Seattle)P49918
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD02913
Protein Interaction databases
DIP (DOE-UCLA)P49918
IntAct (EBI)P49918
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBICDKN1C
SNP : GeneSNP UtahCDKN1C
SNP : HGBaseCDKN1C
Genetic variants : HAPMAPCDKN1C
Somatic Mutations in Cancer : COSMICCDKN1C 
Mutations and Diseases : HGMDCDKN1C
Hereditary diseases : OMIM130650    600856   
Hereditary diseases : GENETests130650    600856   
Diseases : Genetic AssociationCDKN1C
General knowledge
Homologs : HomoloGeneCDKN1C
Homology/Alignments : Family Browser UCSCCDKN1C
Phylogenetic Trees/Animal Genes : TreeFamCDKN1C
Chemical/Protein Interactions : CTD1028
Keywords Ontology : AmiGOregulation of cyclin-dependent protein kinase activity  G1 phase of mitotic cell cycle  negative regulation of transcription from RNA polymerase II promoter  protein kinase inhibitor activity  cyclin-dependent protein kinase inhibitor activity  protein binding  nucleus  nucleolus  cytoplasm  cell cycle  cell cycle arrest  transcription activator activity  transcription repressor activity  positive regulation of transforming growth factor beta receptor signaling pathway  negative regulation of gene-specific transcription  negative regulation of kinase activity  negative regulation of phosphorylation  neuron maturation  negative regulation of epithelial cell proliferation  
Keywords Ontology : EGO-EBIregulation of cyclin-dependent protein kinase activity  G1 phase of mitotic cell cycle  negative regulation of transcription from RNA polymerase II promoter  protein kinase inhibitor activity  cyclin-dependent protein kinase inhibitor activity  protein binding  nucleus  nucleolus  cytoplasm  cell cycle  cell cycle arrest  transcription activator activity  transcription repressor activity  positive regulation of transforming growth factor beta receptor signaling pathway  negative regulation of gene-specific transcription  negative regulation of kinase activity  negative regulation of phosphorylation  neuron maturation  negative regulation of epithelial cell proliferation  
Pathways : BIOCARTA
Pathways : KEGGCell cycle
Other databases
Probes
Probes : ImagenesCDKN1C Related clones (RZPD - Berlin)
Literature
PubMed87 Pubmed reference(s) in Entrez
PubGeneCDKN1C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:33:33 CET 2010
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.