CRK (v-crk sarcoma virus CT10 oncogene homolog (avian))

Identity

Other names	CRKII
HGNC	CRK
Location	17p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CRK   2362
Entrez_Gene	CRK  1398  v-crk sarcoma virus CT10 oncogene homolog (avian)
	Cards
GeneCards	CRK
Ensembl	CRK [Search_View]   ENSG00000167193 [Gene_View]
Genatlas	CRK
GeneLynx	CRK
eGenome	CRK
euGene	1398
	Genomic and cartography
GoldenPath	CRK  -  17p13   chr17:1272208-1306294 -  17p13.3   [Description]    (hg18-March_2006)
Ensembl	CRK - 17p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CRK
	Gene and transcription
Genbank	AK291060 [ ENTREZ ]
Genbank	AU125411 [ ENTREZ ]
Genbank	BC001718 [ ENTREZ ]
Genbank	BC008506 [ ENTREZ ]
Genbank	BC009837 [ ENTREZ ]
RefSeq	NM_005206 [ SRS ]    NM_005206 [ ENTREZ ]
RefSeq	NM_016823 [ SRS ]    NM_016823 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	CRK AceView - NCBI
Unigene	Hs.638121 [ SRS ]    Hs.638121 [ NCBI ]     HS638121 [ spliceNest ]
Fast-db	389 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P46108 [ SRS]    P46108 [ EXPASY ]     P46108 [ INTERPRO ]     P46108 [ UNIPROT ]
Prosite	PS50001 SH2 [ SRS ]    PS50001 SH2 [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR000980 SH2 [ SRS ]    IPR000980 SH2 [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
Interpro	IPR011511 SH3_2 [ SRS ]    IPR011511 SH3_2 [ EBI ]
CluSTr	P46108
Pfam	PF00017 SH2 [ SRS ]    PF00017 SH2 [ Sanger ]    pfam00017 [ NCBI-CDD ]
Pfam	PF00018 SH3_1 [ SRS ]    PF00018 SH3_1 [ Sanger ]    pfam00018 [ NCBI-CDD ]
Pfam	PF07653 SH3_2 [ SRS ]    PF07653 SH3_2 [ Sanger ]    pfam07653 [ NCBI-CDD ]
Smart	SM00252 SH2 [EMBL]
Smart	SM00326 SH3 [EMBL]
Prodom	PD000093 SH2[INRA-Toulouse]
Prodom	P46108 CRK_HUMAN [ Domain structure ]   P46108 CRK_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000093[INRA-Toulouse]
Prodom	P46108 CRK_HUMAN [ Domain structure ]   P46108 CRK_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P46108
PDB	1JU5 [ SRS ]    1JU5 [ PdbSum ],   1JU5 [ IMB ]   1JU5 [ RSDB ]
PDB	2DVJ [ SRS ]    2DVJ [ PdbSum ],   2DVJ [ IMB ]   2DVJ [ RSDB ]
PDB	2EYV [ SRS ]    2EYV [ PdbSum ],   2EYV [ IMB ]   2EYV [ RSDB ]
PDB	2EYW [ SRS ]    2EYW [ PdbSum ],   2EYW [ IMB ]   2EYW [ RSDB ]
PDB	2EYX [ SRS ]    2EYX [ PdbSum ],   2EYX [ IMB ]   2EYX [ RSDB ]
PDB	2EYY [ SRS ]    2EYY [ PdbSum ],   2EYY [ IMB ]   2EYY [ RSDB ]
PDB	2EYZ [ SRS ]    2EYZ [ PdbSum ],   2EYZ [ IMB ]   2EYZ [ RSDB ]
HPRD	01267
	Protein Interaction databases
DIP	P46108
IntAct	P46108
	Polymorphism : SNP, mutations, diseases
OMIM	164762    [ map ]
GENECLINICS	164762
SNP	CRK [dbSNP-NCBI]
SNP	NM_005206 [SNP-NCI]
SNP	NM_016823 [SNP-NCI]
SNP	CRK [GeneSNPs - Utah]  CRK] [HGBASE - SRS]
HAPMAP	CRK [HAPMAP]
COSMIC	CRK [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CRK
	General knowledge
Family Browser	CRK [UCSC Family Browser]
SOURCE	NM_005206
SOURCE	NM_016823
SMD	Hs.638121
SAGE	Hs.638121
GO	protein binding [Amigo]  protein binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	endosome [Amigo]  endosome
GO	cytosol [Amigo]  cytosol
GO	plasma membrane [Amigo]  plasma membrane
GO	regulation of transcription from RNA polymerase II promoter [Amigo]  regulation of transcription from RNA polymerase II promoter
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	actin cytoskeleton organization and biogenesis [Amigo]  actin cytoskeleton organization and biogenesis
GO	SH2 domain binding [Amigo]  SH2 domain binding
GO	protein phosphorylated amino acid binding [Amigo]  protein phosphorylated amino acid binding
BIOCARTA	CXCR4 Signaling Pathway    [Genes]
BIOCARTA	Signaling of Hepatocyte Growth Factor Receptor    [Genes]
KEGG	MAPK signaling pathway
KEGG	Focal adhesion
KEGG	Regulation of actin cytoskeleton
KEGG	Insulin signaling pathway
PubGene	CRK
TreeFam	CRK
CTD	1398 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CRK Related clones (RZPD - Berlin)
	PubMed
PubMed	130 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:06:08 2008