CSNK2A1 (casein kinase 2, alpha 1 polypeptide)

Identity

Other names	CK2A1
	CKII
HGNC	CSNK2A1
Location	20p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CSNK2A1   2457
Entrez_Gene	CSNK2A1  1457  casein kinase 2, alpha 1 polypeptide
	Cards
GeneCards	CSNK2A1
Ensembl	CSNK2A1 [Search_View]   ENSG00000101266 [Gene_View]
Genatlas	CSNK2A1
GeneLynx	CSNK2A1
eGenome	CSNK2A1
euGene	1457
	Genomic and cartography
GoldenPath	CSNK2A1  -  20p13   chr20:411338-472482 -  20p13   [Description]    (hg18-March_2006)
Ensembl	CSNK2A1 - 20p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CSNK2A1
	Gene and transcription
Genbank	AK302583 [ ENTREZ ]
Genbank	AK312535 [ ENTREZ ]
Genbank	AU130091 [ ENTREZ ]
Genbank	AU131227 [ ENTREZ ]
Genbank	AU132198 [ ENTREZ ]
RefSeq	NM_001895 [ SRS ]    NM_001895 [ ENTREZ ]
RefSeq	NM_177559 [ SRS ]    NM_177559 [ ENTREZ ]
RefSeq	NM_177560 [ SRS ]    NM_177560 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	CSNK2A1 AceView - NCBI
Unigene	Hs.644056 [ SRS ]    Hs.644056 [ NCBI ]     HS644056 [ spliceNest ]
Fast-db	903 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P68400 [ SRS]    P68400 [ EXPASY ]     P68400 [ INTERPRO ]     P68400 [ UNIPROT ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	P68400
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P68400 CSK21_HUMAN [ Domain structure ]   P68400 CSK21_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P68400
PDB	1JWH [ SRS ]    1JWH [ PdbSum ],   1JWH [ IMB ]   1JWH [ RSDB ]
PDB	1NA7 [ SRS ]    1NA7 [ PdbSum ],   1NA7 [ IMB ]   1NA7 [ RSDB ]
PDB	1PJK [ SRS ]    1PJK [ PdbSum ],   1PJK [ IMB ]   1PJK [ RSDB ]
PDB	1YMI [ SRS ]    1YMI [ PdbSum ],   1YMI [ IMB ]   1YMI [ RSDB ]
PDB	2PVR [ SRS ]    2PVR [ PdbSum ],   2PVR [ IMB ]   2PVR [ RSDB ]
PDB	2RKP [ SRS ]    2RKP [ PdbSum ],   2RKP [ IMB ]   2RKP [ RSDB ]
PDB	3BQC [ SRS ]    3BQC [ PdbSum ],   3BQC [ IMB ]   3BQC [ RSDB ]
PDB	3BW5 [ SRS ]    3BW5 [ PdbSum ],   3BW5 [ IMB ]   3BW5 [ RSDB ]
PDB	3C13 [ SRS ]    3C13 [ PdbSum ],   3C13 [ IMB ]   3C13 [ RSDB ]
HPRD	00277
	Protein Interaction databases
DIP	P68400
IntAct	P68400
	Polymorphism : SNP, mutations, diseases
OMIM	115440    [ map ]
GENECLINICS	115440
SNP	CSNK2A1 [dbSNP-NCBI]
SNP	NM_001895 [SNP-NCI]
SNP	NM_177559 [SNP-NCI]
SNP	NM_177560 [SNP-NCI]
SNP	CSNK2A1 [GeneSNPs - Utah]  CSNK2A1] [HGBASE - SRS]
HAPMAP	CSNK2A1 [HAPMAP]
COSMIC	CSNK2A1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CSNK2A1
	General knowledge
Family Browser	CSNK2A1 [UCSC Family Browser]
SOURCE	NM_001895
SOURCE	NM_177559
SOURCE	NM_177560
SMD	Hs.644056
SAGE	Hs.644056
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein kinase CK2 activity [Amigo]  protein kinase CK2 activity
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	plasma membrane [Amigo]  plasma membrane
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	signal transduction [Amigo]  signal transduction
GO	Wnt receptor signaling pathway [Amigo]  Wnt receptor signaling pathway
GO	transferase activity [Amigo]  transferase activity
GO	protein N-terminus binding [Amigo]  protein N-terminus binding
BIOCARTA	Lissencephaly gene (LIS1) in neuronal migration and development    [Genes]
BIOCARTA	TPO Signaling Pathway    [Genes]
BIOCARTA	EGF Signaling Pathway    [Genes]
BIOCARTA	EPO Signaling Pathway    [Genes]
BIOCARTA	IGF-1 Signaling Pathway    [Genes]
BIOCARTA	IL 2 signaling pathway    [Genes]
BIOCARTA	IL 6 signaling pathway    [Genes]
BIOCARTA	Insulin Signaling Pathway    [Genes]
BIOCARTA	Nerve growth factor pathway (NGF)    [Genes]
BIOCARTA	PDGF Signaling Pathway    [Genes]
BIOCARTA	WNT Signaling Pathway    [Genes]
KEGG	Wnt signaling pathway
KEGG	Adherens junction
KEGG	Tight junction
PubGene	CSNK2A1
TreeFam	CSNK2A1
CTD	1457 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CSNK2A1 Related clones (RZPD - Berlin)
	PubMed
PubMed	316 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:06:18 2008