CUL2 (cullin 2)

Identity

Other names	MGC131970
HGNC	CUL2
Location	10p11.2
Location_base_pair	Starts at 35338812 and ends at 35419300 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CUL2   2552
Entrez_Gene	CUL2  8453  cullin 2
	Cards
GeneCards	CUL2
Ensembl	CUL2 [Search_View]   ENSG00000108094 [Gene_View]
Genatlas	CUL2
GeneLynx	CUL2
eGenome	CUL2
euGene	8453
	Genomic and cartography
GoldenPath	CUL2  -  10p11.2   chr10:35338812-35419300 -  10p11.21   [Description]    (hg18-March_2006)
Ensembl	CUL2 - 10p11.21 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CUL2
	Gene and transcription
Genbank	AF126404 [ ENTREZ ]
Genbank	AK095217 [ ENTREZ ]
Genbank	AK310225 [ ENTREZ ]
Genbank	AL832733 [ ENTREZ ]
Genbank	BC009591 [ ENTREZ ]
RefSeq	NM_003591 [ SRS ]    NM_003591 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_008705 [ SRS ]    NT_008705 [ ENTREZ ]
RefSeq	NW_001837932 [ SRS ]    NW_001837932 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
AceView	CUL2 AceView - NCBI
Unigene	Hs.82919 [ SRS ]    Hs.82919 [ NCBI ]     HS82919 [ spliceNest ]
Fast-db	8755 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q13617 [ SRS]    Q13617 [ EXPASY ]     Q13617 [ INTERPRO ]     Q13617 [ UNIPROT ]
Prosite	PS01256 CULLIN_1 [ SRS ]    PS01256 CULLIN_1 [ Expasy ]
Prosite	PS50069 CULLIN_2 [ SRS ]    PS50069 CULLIN_2 [ Expasy ]
Interpro	IPR016157 Cullin_CS [ SRS ]    IPR016157 Cullin_CS [ EBI ]
Interpro	IPR016158 Cullin_homology [ SRS ]    IPR016158 Cullin_homology [ EBI ]
Interpro	IPR001373 Cullin_N [ SRS ]    IPR001373 Cullin_N [ EBI ]
Interpro	IPR011991 Wing_hlx_DNA_bd [ SRS ]    IPR011991 Wing_hlx_DNA_bd [ EBI ]
CluSTr	Q13617
Pfam	PF00888 Cullin [ SRS ]    PF00888 Cullin [ Sanger ]    pfam00888 [ NCBI-CDD ]
Smart	SM00182 CULLIN [EMBL]
Blocks	Q13617
HPRD	06786
	Protein Interaction databases
DIP	Q13617
IntAct	Q13617
	Polymorphism : SNP, mutations, diseases
OMIM	603135    [ map ]
GENECLINICS	603135
SNP	CUL2 [dbSNP-NCBI]
SNP	NM_003591 [SNP-NCI]
SNP	CUL2 [GeneSNPs - Utah]  CUL2] [HGBASE - SRS]
HAPMAP	CUL2 [HAPMAP]
COSMIC	CUL2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CUL2
	General knowledge
Family Browser	CUL2 [UCSC Family Browser]
SOURCE	NM_003591
SMD	Hs.82919
SAGE	Hs.82919
GO	G1/S transition of mitotic cell cycle [Amigo]  G1/S transition of mitotic cell cycle
GO	protein binding [Amigo]  protein binding
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	cell cycle arrest [Amigo]  cell cycle arrest
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	induction of apoptosis by intracellular signals [Amigo]  induction of apoptosis by intracellular signals
GO	cullin-RING ubiquitin ligase complex [Amigo]  cullin-RING ubiquitin ligase complex
GO	ubiquitin protein ligase binding [Amigo]  ubiquitin protein ligase binding
KEGG	Ubiquitin mediated proteolysis
PubGene	CUL2
TreeFam	CUL2
CTD	8453 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CUL2 Related clones (RZPD - Berlin)
	PubMed
PubMed	29 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:37:03 2008