DCLK1 (doublecortin-like kinase 1)

Identity

Other names	DCAMKL1
	DCDC3A
	DCLK
	KIAA0369
HGNC	DCLK1
Location	13q13.3
Location_base_pair	Starts at 35243478 and ends at 35603443 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	DCLK1   2700
Entrez_Gene	DCLK1  9201  doublecortin-like kinase 1
	Cards
GeneCards	DCLK1
Ensembl	DCLK1 [Search_View]   ENSG00000133083 [Gene_View]
Genatlas	DCLK1
GeneLynx	DCLK1
eGenome	DCLK1
euGene	9201
	Genomic and cartography
GoldenPath	DCLK1  -  13q13.3   chr13:35243478-35603443 -  13q13.3   [Description]    (hg18-March_2006)
Ensembl	DCLK1 - 13q13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DCLK1
	Gene and transcription
Genbank	AB002367 [ ENTREZ ]
Genbank	AF052152 [ ENTREZ ]
Genbank	AF070534 [ ENTREZ ]
Genbank	AK308925 [ ENTREZ ]
Genbank	AK311183 [ ENTREZ ]
RefSeq	NM_004734 [ SRS ]    NM_004734 [ ENTREZ ]
RefSeq	AC_000056 [ SRS ]    AC_000056 [ ENTREZ ]
RefSeq	AC_000145 [ SRS ]    AC_000145 [ ENTREZ ]
RefSeq	NC_000013 [ SRS ]    NC_000013 [ ENTREZ ]
RefSeq	NT_024524 [ SRS ]    NT_024524 [ ENTREZ ]
RefSeq	NW_001838072 [ SRS ]    NW_001838072 [ ENTREZ ]
RefSeq	NW_925473 [ SRS ]    NW_925473 [ ENTREZ ]
AceView	DCLK1 AceView - NCBI
Unigene	Hs.593611 [ SRS ]    Hs.593611 [ NCBI ]     HS593611 [ spliceNest ]
Fast-db	3017 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O15075 [ SRS]    O15075 [ EXPASY ]     O15075 [ INTERPRO ]     O15075 [ UNIPROT ]
Prosite	PS50309 DC [ SRS ]    PS50309 DC [ Expasy ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR003533 DCX [ SRS ]    IPR003533 DCX [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	O15075
Pfam	PF03607 DCX [ SRS ]    PF03607 DCX [ Sanger ]    pfam03607 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00537 DCX [EMBL]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	O15075 DCLK1_HUMAN [ Domain structure ]   O15075 DCLK1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	O15075
PDB	1MFW [ SRS ]    1MFW [ PdbSum ],   1MFW [ IMB ]   1MFW [ RSDB ]
PDB	1MG4 [ SRS ]    1MG4 [ PdbSum ],   1MG4 [ IMB ]   1MG4 [ RSDB ]
PDB	1UF0 [ SRS ]    1UF0 [ PdbSum ],   1UF0 [ IMB ]   1UF0 [ RSDB ]
HPRD	09202
	Protein Interaction databases
DIP	O15075
IntAct	O15075
	Polymorphism : SNP, mutations, diseases
OMIM	604742    [ map ]
GENECLINICS	604742
SNP	DCLK1 [dbSNP-NCBI]
SNP	NM_004734 [SNP-NCI]
SNP	DCLK1 [GeneSNPs - Utah]  DCLK1] [HGBASE - SRS]
HAPMAP	DCLK1 [HAPMAP]
COSMIC	DCLK1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DCLK1
	General knowledge
Family Browser	DCLK1 [UCSC Family Browser]
SOURCE	NM_004734
SMD	Hs.593611
SAGE	Hs.593611
Enzyme	2.7.11.1 [ Enzyme-Expasy ]   2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   2.7.11.1 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	receptor signaling protein activity [Amigo]  receptor signaling protein activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	central nervous system development [Amigo]  central nervous system development
GO	endosome transport [Amigo]  endosome transport
GO	kinase activity [Amigo]  kinase activity
GO	transferase activity [Amigo]  transferase activity
GO	cell differentiation [Amigo]  cell differentiation
PubGene	DCLK1
TreeFam	DCLK1
CTD	9201 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DCLK1 Related clones (RZPD - Berlin)
	PubMed
PubMed	12 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:09:46 2008