DDX4 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 4)

Identity

Other names	MGC111074
	VASA
HGNC	DDX4
Location	5p15.2-p13.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DDX4   18700
Entrez_Gene	DDX4  54514  DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
	Cards
GeneCards	DDX4
Ensembl	DDX4 [Search_View]   ENSG00000152670 [Gene_View]
Genatlas	DDX4
GeneLynx	DDX4
eGenome	DDX4
euGene	54514
	Genomic and cartography
GoldenPath	DDX4  -     chr5:55070533-55148362 +  5q11.2   [Description]    (hg18-March_2006)
Ensembl	DDX4 - 5q11.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DDX4
	Gene and transcription
Genbank	AF262962 [ ENTREZ ]
Genbank	AK093439 [ ENTREZ ]
Genbank	AK292417 [ ENTREZ ]
Genbank	AK308300 [ ENTREZ ]
Genbank	AL137462 [ ENTREZ ]
RefSeq	NM_024415 [ SRS ]    NM_024415 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_006713 [ SRS ]    NT_006713 [ ENTREZ ]
RefSeq	NW_001838934 [ SRS ]    NW_001838934 [ ENTREZ ]
RefSeq	NW_922607 [ SRS ]    NW_922607 [ ENTREZ ]
AceView	DDX4 AceView - NCBI
Unigene	Hs.223581 [ SRS ]    Hs.223581 [ NCBI ]     HS223581 [ spliceNest ]
Fast-db	4241 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9NQI0 [ SRS]    Q9NQI0 [ EXPASY ]     Q9NQI0 [ INTERPRO ]     Q9NQI0 [ UNIPROT ]
Prosite	PS00039 DEAD_ATP_HELICASE [ SRS ]    PS00039 DEAD_ATP_HELICASE [ Expasy ]
Prosite	PS51192 HELICASE_ATP_BIND_1 [ SRS ]    PS51192 HELICASE_ATP_BIND_1 [ Expasy ]
Prosite	PS51194 HELICASE_CTER [ SRS ]    PS51194 HELICASE_CTER [ Expasy ]
Prosite	PS51195 Q_MOTIF [ SRS ]    PS51195 Q_MOTIF [ Expasy ]
Interpro	IPR014001 DEAD-like_N [ SRS ]    IPR014001 DEAD-like_N [ EBI ]
Interpro	IPR001650 DNA/RNA_helicase_C [ SRS ]    IPR001650 DNA/RNA_helicase_C [ EBI ]
Interpro	IPR011545 DNA/RNA_helicase_DEAD/DEAH_N [ SRS ]    IPR011545 DNA/RNA_helicase_DEAD/DEAH_N [ EBI ]
Interpro	IPR014021 Helicase_SF1/SF2_ATP-bd [ SRS ]    IPR014021 Helicase_SF1/SF2_ATP-bd [ EBI ]
Interpro	IPR000629 RNA-helicase_DEAD-box_CS [ SRS ]    IPR000629 RNA-helicase_DEAD-box_CS [ EBI ]
Interpro	IPR014014 RNA_helicase_DEAD_Q_motif [ SRS ]    IPR014014 RNA_helicase_DEAD_Q_motif [ EBI ]
CluSTr	Q9NQI0
Pfam	PF00270 DEAD [ SRS ]    PF00270 DEAD [ Sanger ]    pfam00270 [ NCBI-CDD ]
Pfam	PF00271 Helicase_C [ SRS ]    PF00271 Helicase_C [ Sanger ]    pfam00271 [ NCBI-CDD ]
Smart	SM00487 DEXDc [EMBL]
Smart	SM00490 HELICc [EMBL]
Blocks	Q9NQI0
HPRD	05593
	Protein Interaction databases
DIP	Q9NQI0
IntAct	Q9NQI0
	Polymorphism : SNP, mutations, diseases
OMIM	605281    [ map ]
GENECLINICS	605281
SNP	DDX4 [dbSNP-NCBI]
SNP	NM_024415 [SNP-NCI]
SNP	DDX4 [GeneSNPs - Utah]  DDX4] [HGBASE - SRS]
HAPMAP	DDX4 [HAPMAP]
COSMIC	DDX4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DDX4
	General knowledge
Family Browser	DDX4 [UCSC Family Browser]
SOURCE	NM_024415
SMD	Hs.223581
SAGE	Hs.223581
Enzyme	3.6.1.- [ Enzyme-Expasy ]   3.6.1.- [ Enzyme-SRS ]   3.6.1.- [ IntEnz-EBI ]   3.6.1.- [ BRENDA ]   3.6.1.- [ KEGG ]   3.6.1.- [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	nucleic acid binding [Amigo]  nucleic acid binding
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	ATP-dependent helicase activity [Amigo]  ATP-dependent helicase activity
GO	hydrolase activity [Amigo]  hydrolase activity
PubGene	DDX4
TreeFam	DDX4
CTD	54514 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DDX4 Related clones (RZPD - Berlin)
	PubMed
PubMed	7 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:07:34 2008