DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58)

Identity

Other names	DKFZp434J1111
	DKFZp686N19181
	FLJ13599
	RIG-I
HGNC	DDX58
Location	9p12
Location_base_pair	Starts at 32445300 and ends at 32516322 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DDX58   19102
Entrez_Gene	DDX58  23586  DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
	Cards
GeneCards	DDX58
Ensembl	DDX58 [Search_View]   ENSG00000107201 [Gene_View]
Genatlas	DDX58
GeneLynx	DDX58
eGenome	DDX58
euGene	23586
	Genomic and cartography
GoldenPath	DDX58  -  9p12   chr9:32445300-32516322 -  9p21.1   [Description]    (hg18-March_2006)
Ensembl	DDX58 - 9p21.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DDX58
	Gene and transcription
Genbank	AA862613 [ ENTREZ ]
Genbank	AF038963 [ ENTREZ ]
Genbank	AK023661 [ ENTREZ ]
Genbank	AK125989 [ ENTREZ ]
Genbank	AK315040 [ ENTREZ ]
RefSeq	NM_014314 [ SRS ]    NM_014314 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	DDX58 AceView - NCBI
Unigene	Hs.190622 [ SRS ]    Hs.190622 [ NCBI ]     HS190622 [ spliceNest ]
Fast-db	3972 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O95786 [ SRS]    O95786 [ EXPASY ]     O95786 [ INTERPRO ]     O95786 [ UNIPROT ]
Prosite	PS50209 CARD [ SRS ]    PS50209 CARD [ Expasy ]
Prosite	PS51192 HELICASE_ATP_BIND_1 [ SRS ]    PS51192 HELICASE_ATP_BIND_1 [ Expasy ]
Prosite	PS51194 HELICASE_CTER [ SRS ]    PS51194 HELICASE_CTER [ Expasy ]
Interpro	IPR003593 AAA+_ATPase_core [ SRS ]    IPR003593 AAA+_ATPase_core [ EBI ]
Interpro	IPR001315 CARD [ SRS ]    IPR001315 CARD [ EBI ]
Interpro	IPR014001 DEAD-like_N [ SRS ]    IPR014001 DEAD-like_N [ EBI ]
Interpro	IPR001650 DNA/RNA_helicase_C [ SRS ]    IPR001650 DNA/RNA_helicase_C [ EBI ]
Interpro	IPR011545 DNA/RNA_helicase_DEAD/DEAH_N [ SRS ]    IPR011545 DNA/RNA_helicase_DEAD/DEAH_N [ EBI ]
Interpro	IPR014021 Helicase_SF1/SF2_ATP-bd [ SRS ]    IPR014021 Helicase_SF1/SF2_ATP-bd [ EBI ]
CluSTr	O95786
Pfam	PF00270 DEAD [ SRS ]    PF00270 DEAD [ Sanger ]    pfam00270 [ NCBI-CDD ]
Pfam	PF00271 Helicase_C [ SRS ]    PF00271 Helicase_C [ Sanger ]    pfam00271 [ NCBI-CDD ]
Smart	SM00382 AAA [EMBL]
Smart	SM00487 DEXDc [EMBL]
Smart	SM00490 HELICc [EMBL]
Blocks	O95786
PDB	2QFB [ SRS ]    2QFB [ PdbSum ],   2QFB [ IMB ]   2QFB [ RSDB ]
PDB	2QFD [ SRS ]    2QFD [ PdbSum ],   2QFD [ IMB ]   2QFD [ RSDB ]
PDB	2RMJ [ SRS ]    2RMJ [ PdbSum ],   2RMJ [ IMB ]   2RMJ [ RSDB ]
HPRD	13131
	Protein Interaction databases
DIP	O95786
IntAct	O95786
	Polymorphism : SNP, mutations, diseases
OMIM	609631    [ map ]
GENECLINICS	609631
SNP	DDX58 [dbSNP-NCBI]
SNP	NM_014314 [SNP-NCI]
SNP	DDX58 [GeneSNPs - Utah]  DDX58] [HGBASE - SRS]
HAPMAP	DDX58 [HAPMAP]
COSMIC	DDX58 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DDX58
	General knowledge
Family Browser	DDX58 [UCSC Family Browser]
SOURCE	NM_014314
SMD	Hs.190622
SAGE	Hs.190622
Enzyme	3.6.1.- [ Enzyme-Expasy ]   3.6.1.- [ Enzyme-SRS ]   3.6.1.- [ IntEnz-EBI ]   3.6.1.- [ BRENDA ]   3.6.1.- [ KEGG ]   3.6.1.- [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	RNA binding [Amigo]  RNA binding
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	ATP-dependent helicase activity [Amigo]  ATP-dependent helicase activity
GO	response to virus [Amigo]  response to virus
GO	hydrolase activity [Amigo]  hydrolase activity
GO	nucleoside-triphosphatase activity [Amigo]  nucleoside-triphosphatase activity
GO	innate immune response [Amigo]  innate immune response
PubGene	DDX58
TreeFam	DDX58
CTD	23586 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DDX58 Related clones (RZPD - Berlin)
	PubMed
PubMed	43 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:38:01 2008