DEFA1 (defensin, alpha 1)

Identity

Other names	DEF1
	DEFA2
	HNP-1
	HP-1
	MGC138393
	MRS
HGNC	DEFA1
Location	8p23.1
Location_base_pair	Starts at 6822581 and ends at 6825012 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DEFA1   2761
Entrez_Gene	DEFA1  1667  defensin, alpha 1
	Cards
GeneCards	DEFA1
Ensembl	DEFA1 [Search_View]   ENSG00000206047 [Gene_View]
Genatlas	DEFA1
GeneLynx	DEFA1
eGenome	DEFA1
euGene	1667
	Genomic and cartography
GoldenPath	DEFA1  -  8p23.1   chr8:6822581-6825012 -  8p23.1   [Description]    (hg18-March_2006)
Ensembl	DEFA1 - 8p23.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DEFA1
	Gene and transcription
Genbank	BC069423 [ ENTREZ ]
Genbank	BC093791 [ ENTREZ ]
Genbank	BC112188 [ ENTREZ ]
Genbank	DQ890545 [ ENTREZ ]
Genbank	DQ890546 [ ENTREZ ]
RefSeq	NM_004084 [ SRS ]    NM_004084 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_023736 [ SRS ]    NT_023736 [ ENTREZ ]
AceView	DEFA1 AceView - NCBI
Unigene	Hs.380781 [ SRS ]    Hs.380781 [ NCBI ]     HS380781 [ spliceNest ]
	Protein : pattern, domain, 3D structure
SwissProt	P59665 [ SRS]    P59665 [ EXPASY ]     P59665 [ INTERPRO ]     P59665 [ UNIPROT ]
Prosite	PS00269 DEFENSIN [ SRS ]    PS00269 DEFENSIN [ Expasy ]
Interpro	IPR016327 Alpha-defensin [ SRS ]    IPR016327 Alpha-defensin [ EBI ]
Interpro	IPR006081 Defensin_alpha [ SRS ]    IPR006081 Defensin_alpha [ EBI ]
Interpro	IPR006080 Defensin_mammal [ SRS ]    IPR006080 Defensin_mammal [ EBI ]
Interpro	IPR002366 Defensin_propep [ SRS ]    IPR002366 Defensin_propep [ EBI ]
CluSTr	P59665
Pfam	PF00323 Defensin_1 [ SRS ]    PF00323 Defensin_1 [ Sanger ]    pfam00323 [ NCBI-CDD ]
Pfam	PF00879 Defensin_propep [ SRS ]    PF00879 Defensin_propep [ Sanger ]    pfam00879 [ NCBI-CDD ]
Smart	SM00048 DEFSN [EMBL]
Blocks	P59665
PDB	1DFN [ SRS ]    1DFN [ PdbSum ],   1DFN [ IMB ]   1DFN [ RSDB ]
PDB	2PM1 [ SRS ]    2PM1 [ PdbSum ],   2PM1 [ IMB ]   2PM1 [ RSDB ]
HPRD	00499
	Protein Interaction databases
DIP	P59665
IntAct	P59665
	Polymorphism : SNP, mutations, diseases
OMIM	125220    [ map ]
GENECLINICS	125220
SNP	DEFA1 [dbSNP-NCBI]
SNP	NM_004084 [SNP-NCI]
SNP	DEFA1 [GeneSNPs - Utah]  DEFA1] [HGBASE - SRS]
HAPMAP	DEFA1 [HAPMAP]
HGMD	DEFA1
	General knowledge
Family Browser	DEFA1 [UCSC Family Browser]
SOURCE	NM_004084
SMD	Hs.380781
SAGE	Hs.380781
GO	extracellular region [Amigo]  extracellular region
GO	xenobiotic metabolic process [Amigo]  xenobiotic metabolic process
GO	chemotaxis [Amigo]  chemotaxis
GO	immune response [Amigo]  immune response
GO	response to virus [Amigo]  response to virus
GO	defense response to bacterium [Amigo]  defense response to bacterium
GO	defense response to fungus [Amigo]  defense response to fungus
KEGG	Neuroactive ligand-receptor interaction
PubGene	DEFA1
TreeFam	DEFA1
CTD	1667 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DEFA1 Related clones (RZPD - Berlin)
	PubMed
PubMed	58 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:38:05 2008