DFFA (DNA fragmentation factor, 45kDa, alpha polypeptide)

Identity

Other names	DFF-45
	DFF1
	ICAD
HGNC	DFFA
Location	1p36.3-p36.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DFFA   2772
Entrez_Gene	DFFA  1676  DNA fragmentation factor, 45kDa, alpha polypeptide
	Cards
GeneCards	DFFA
Ensembl	DFFA [Search_View]   ENSG00000160049 [Gene_View]
Genatlas	DFFA
GeneLynx	DFFA
eGenome	DFFA
euGene	1676
	Genomic and cartography
GoldenPath	DFFA  -     chr1:10443190-10455200 -  1p36.22   [Description]    (hg18-March_2006)
Ensembl	DFFA - 1p36.22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DFFA
	Gene and transcription
Genbank	AF087573 [ ENTREZ ]
Genbank	AF103799 [ ENTREZ ]
Genbank	AK222546 [ ENTREZ ]
Genbank	AK313317 [ ENTREZ ]
Genbank	AU121791 [ ENTREZ ]
RefSeq	NM_004401 [ SRS ]    NM_004401 [ ENTREZ ]
RefSeq	NM_213566 [ SRS ]    NM_213566 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NT_021937 [ SRS ]    NT_021937 [ ENTREZ ]
RefSeq	NW_001838523 [ SRS ]    NW_001838523 [ ENTREZ ]
RefSeq	NW_923572 [ SRS ]    NW_923572 [ ENTREZ ]
AceView	DFFA AceView - NCBI
Unigene	Hs.484782 [ SRS ]    Hs.484782 [ NCBI ]     HS484782 [ spliceNest ]
Fast-db	4735 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O00273 [ SRS]    O00273 [ EXPASY ]     O00273 [ INTERPRO ]     O00273 [ UNIPROT ]
Prosite	PS51135 CIDE_N [ SRS ]    PS51135 CIDE_N [ Expasy ]
Interpro	IPR003508 CAD [ SRS ]    IPR003508 CAD [ EBI ]
Interpro	IPR015121 DFF-C [ SRS ]    IPR015121 DFF-C [ EBI ]
Interpro	IPR017299 DNA_fragmentation_factor_asu [ SRS ]    IPR017299 DNA_fragmentation_factor_asu [ EBI ]
CluSTr	O00273
Pfam	PF02017 CIDE-N [ SRS ]    PF02017 CIDE-N [ Sanger ]    pfam02017 [ NCBI-CDD ]
Pfam	PF09033 DFF-C [ SRS ]    PF09033 DFF-C [ Sanger ]    pfam09033 [ NCBI-CDD ]
Smart	SM00266 CAD [EMBL]
Blocks	O00273
PDB	1IBX [ SRS ]    1IBX [ PdbSum ],   1IBX [ IMB ]   1IBX [ RSDB ]
PDB	1IYR [ SRS ]    1IYR [ PdbSum ],   1IYR [ IMB ]   1IYR [ RSDB ]
PDB	1KOY [ SRS ]    1KOY [ PdbSum ],   1KOY [ IMB ]   1KOY [ RSDB ]
HPRD	03531
	Protein Interaction databases
DIP	O00273
IntAct	O00273
	Polymorphism : SNP, mutations, diseases
OMIM	601882    [ map ]
GENECLINICS	601882
SNP	DFFA [dbSNP-NCBI]
SNP	NM_004401 [SNP-NCI]
SNP	NM_213566 [SNP-NCI]
SNP	DFFA [GeneSNPs - Utah]  DFFA] [HGBASE - SRS]
HAPMAP	DFFA [HAPMAP]
HGMD	DFFA
	General knowledge
Family Browser	DFFA [UCSC Family Browser]
SOURCE	NM_004401
SOURCE	NM_213566
SMD	Hs.484782
SAGE	Hs.484782
GO	caspase-activated deoxyribonuclease activity [Amigo]  caspase-activated deoxyribonuclease activity
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	DNA fragmentation during apoptosis [Amigo]  DNA fragmentation during apoptosis
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	identical protein binding [Amigo]  identical protein binding
GO	negative regulation of apoptosis [Amigo]  negative regulation of apoptosis
BIOCARTA	Apoptotic DNA fragmentation and tissue homeostasis    [Genes]
BIOCARTA	HIV-I Nef: negative effector of Fas and TNF    [Genes]
BIOCARTA	Caspase Cascade in Apoptosis    [Genes]
BIOCARTA	Induction of apoptosis through DR3 and DR4/5 Death Receptors    [Genes]
BIOCARTA	FAS signaling pathway ( CD95 )    [Genes]
BIOCARTA	Role of Mitochondria in Apoptotic Signaling    [Genes]
BIOCARTA	Granzyme A mediated Apoptosis Pathway    [Genes]
BIOCARTA	TNFR1 Signaling Pathway    [Genes]
KEGG	Apoptosis
PubGene	DFFA
TreeFam	DFFA
CTD	1676 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DFFA Related clones (RZPD - Berlin)
	PubMed
PubMed	40 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:07:46 2008