DLC1 (deleted in liver cancer 1)

Identity

Other names	ARHGAP7
	FLJ21120
	HP
	STARD12
	p122-RhoGAP
HGNC	DLC1
Location	8p22
Location_base_pair	Starts at 12985243 and ends at 13035180 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DLC1   2897
Entrez_Gene	DLC1  10395  deleted in liver cancer 1
	Cards
GeneCards	DLC1
Ensembl	DLC1 [Search_View]   ENSG00000164741 [Gene_View]
Genatlas	DLC1
GeneLynx	DLC1
eGenome	DLC1
euGene	10395
	Genomic and cartography
GoldenPath	DLC1  -  8p22   chr8:12985243-13035180 -  8p22   [Description]    (hg18-March_2006)
Ensembl	DLC1 - 8p22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DLC1
	Gene and transcription
Genbank	AB051510 [ ENTREZ ]
Genbank	AF026219 [ ENTREZ ]
Genbank	AF035119 [ ENTREZ ]
Genbank	AK023128 [ ENTREZ ]
Genbank	AK024773 [ ENTREZ ]
RefSeq	NM_006094 [ SRS ]    NM_006094 [ ENTREZ ]
RefSeq	NM_024767 [ SRS ]    NM_024767 [ ENTREZ ]
RefSeq	NM_182643 [ SRS ]    NM_182643 [ ENTREZ ]
RefSeq	AC_000051 [ SRS ]    AC_000051 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_030737 [ SRS ]    NT_030737 [ ENTREZ ]
RefSeq	NW_001839126 [ SRS ]    NW_001839126 [ ENTREZ ]
RefSeq	NW_923907 [ SRS ]    NW_923907 [ ENTREZ ]
AceView	DLC1 AceView - NCBI
Unigene	Hs.134296 [ SRS ]    Hs.134296 [ NCBI ]     HS134296 [ spliceNest ]
Fast-db	1473 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q45XF9 [ SRS]    Q45XF9 [ EXPASY ]     Q45XF9 [ INTERPRO ]     Q45XF9 [ UNIPROT ]
CluSTr	Q45XF9
Blocks	Q45XF9
HPRD	05035
	Protein Interaction databases
DIP	Q45XF9
IntAct	Q45XF9
	Polymorphism : SNP, mutations, diseases
OMIM	604258    [ map ]
GENECLINICS	604258
SNP	DLC1 [dbSNP-NCBI]
SNP	NM_006094 [SNP-NCI]
SNP	NM_024767 [SNP-NCI]
SNP	NM_182643 [SNP-NCI]
SNP	DLC1 [GeneSNPs - Utah]  DLC1] [HGBASE - SRS]
HAPMAP	DLC1 [HAPMAP]
COSMIC	DLC1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DLC1
	General knowledge
Family Browser	DLC1 [UCSC Family Browser]
SOURCE	NM_006094
SOURCE	NM_024767
SOURCE	NM_182643
SMD	Hs.134296
SAGE	Hs.134296
GO	neural tube closure [Amigo]  neural tube closure
GO	heart morphogenesis [Amigo]  heart morphogenesis
GO	GTPase activator activity [Amigo]  GTPase activator activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	caveola [Amigo]  caveola
GO	focal adhesion [Amigo]  focal adhesion
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	caspase activation [Amigo]  caspase activation
GO	signal transduction [Amigo]  signal transduction
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	regulation of cell shape [Amigo]  regulation of cell shape
GO	hindbrain morphogenesis [Amigo]  hindbrain morphogenesis
GO	negative regulation of cell migration [Amigo]  negative regulation of cell migration
GO	negative regulation of cell migration [Amigo]  negative regulation of cell migration
GO	Rac GTPase activator activity [Amigo]  Rac GTPase activator activity
GO	forebrain development [Amigo]  forebrain development
GO	regulation of actin cytoskeleton organization and biogenesis [Amigo]  regulation of actin cytoskeleton organization and biogenesis
GO	negative regulation of Rho protein signal transduction [Amigo]  negative regulation of Rho protein signal transduction
GO	positive regulation of protein amino acid dephosphorylation [Amigo]  positive regulation of protein amino acid dephosphorylation
GO	SH2 domain binding [Amigo]  SH2 domain binding
GO	focal adhesion formation [Amigo]  focal adhesion formation
GO	negative regulation of stress fiber formation [Amigo]  negative regulation of stress fiber formation
PubGene	DLC1
TreeFam	DLC1
CTD	10395 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DLC1 Related clones (RZPD - Berlin)
	PubMed
PubMed	33 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:38:28 2008