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DSC2 (desmocollin 2)

Identity

Other namesARVD11
CDHF2
DG2
DGII/III
DKFZp686I11137
DSC3
HGNC (Hugo) DSC2
Location 18q12.1
Location_base_pair Starts at 26899940 and ends at 26936386 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DSC2   3036
Entrez_Gene (NCBI)DSC2  1824  desmocollin 2
Cards
GeneCards (Weizmann)DSC2
Ensembl (Hinxton)ENSG00000134755 [Gene_View]  DSC2 [Vega]
AceView (NCBI)DSC2
Genatlas (Paris)DSC2
euGene (Indiana)1824
SOURCE (Stanford)NM_004949 NM_024422
Gene Expression (Array Express) ENSG00000134755
Genomic and cartography
GoldenPath (UCSC)DSC2  -  18q12.1   chr18:26899940-26936386 -  18q12.1   [Description]    (hg18-March_2006)
EnsemblDSC2 - 18q12.1 [CytoView]
Mapping of homologs : NCBIDSC2 [Mapview]
OMIM125645   610476   
Gene and transcription
Gene : Genbank (Entrez)AK290313 AK297029 BC063291 BE813598 BU735677
Reference sequence (RefSeq transcript) :SRSNM_004949 NM_024422
Reference transcript : EntrezNM_004949 NM_024422
RefSeq genomic : SRSAC_000061 AC_000150 NC_000018 NG_008208 NT_010966 NW_001838467 NW_927095
RefSeq genomic : EntrezAC_000061 AC_000150 NC_000018 NG_008208 NT_010966 NW_001838467 NW_927095
Consensus coding sequences : CCDS NCBIDSC2
Cluster EST : UnigeneHs.95612 [ SRS ] Hs.95612 [ NCBI ]
Alternative Splicing : Fast-db (Paris)2956
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ02487 (SRS) Q02487 (Expasy) Q02487 (Uniprot)
With graphics : InterProQ02487
Splice isoforms : VarSplice FASTAQ02487(VarSplice FASTA)
Domaine pattern : Prosite (SRS)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domain pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (SRS)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Cadherin_pro    Desmo_cadherin    Desmocollin   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Cadherin_pro    Desmo_cadherin    Desmocollin   
Related proteins : CluSTrQ02487
Domain families : Pfam SRSCadherin (PF00028)    Cadherin_C (PF01049)    Cadherin_pro (PF08758)   
Domain families : Pfam SangerCadherin (PF00028)    Cadherin_C (PF01049)    Cadherin_pro (PF08758)   
Domain families : Pfam NCBIpfam00028    pfam01049    pfam08758   
Domain families : Smart EMBLCA (SM00112)  
Blocks (Seattle)Q02487
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD00512
Protein Interaction databases
DIP (DOE-UCLA)Q02487
IntAct (EBI)Q02487
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIDSC2
SNP : GeneSNP UtahDSC2
SNP : HGBaseDSC2
Genetic variants : HAPMAPDSC2
Somatic Mutations in Cancer : COSMICDSC2 
Mutations and Diseases : HGMDDSC2
Hereditary diseases : OMIM125645    610476   
Hereditary diseases : GENETests125645    610476   
Diseases : Genetic AssociationDSC2
General knowledge
Homologs : HomoloGeneDSC2
Homology/Alignments : Family Browser UCSCDSC2
Phylogenetic Trees/Animal Genes : TreeFamDSC2
Chemical/Protein Interactions : CTD1824
Keywords Ontology : AmiGOcalcium ion binding  protein binding  plasma membrane  cell adhesion  homophilic cell adhesion  integral to membrane  cell junction  desmosome  
Keywords Ontology : EGO-EBIcalcium ion binding  protein binding  plasma membrane  cell adhesion  homophilic cell adhesion  integral to membrane  cell junction  desmosome  
Pathways : BIOCARTA
Pathways : KEGGCell Communication
Other databases
Probes
Probes : ImagenesDSC2 Related clones (RZPD - Berlin)
Literature
PubMed35 Pubmed reference(s) in Entrez
PubGeneDSC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:33:36 CET 2010
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