DYRK1A (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A)

Identity

Other names	DYRK
	DYRK1
	HP86
	MNB
	MNBH
HGNC	DYRK1A
Location	21q22.13
Location_base_pair	Starts at 37714472 and ends at 37809549 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DYRK1A   3091
Entrez_Gene	DYRK1A  1859  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
	Cards
GeneCards	DYRK1A
Ensembl	DYRK1A [Search_View]   ENSG00000157540 [Gene_View]
Genatlas	DYRK1A
GeneLynx	DYRK1A
eGenome	DYRK1A
euGene	1859
	Genomic and cartography
GoldenPath	DYRK1A  -  21q22.13   chr21:37714472-37809549 +  21q22.13   [Description]    (hg18-March_2006)
Ensembl	DYRK1A - 21q22.13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DYRK1A
	Gene and transcription
Genbank	AB015282 [ ENTREZ ]
Genbank	AB015283 [ ENTREZ ]
Genbank	AB015284 [ ENTREZ ]
Genbank	AF108830 [ ENTREZ ]
Genbank	AJ001870 [ ENTREZ ]
RefSeq	NM_001396 [ SRS ]    NM_001396 [ ENTREZ ]
RefSeq	NM_101395 [ SRS ]    NM_101395 [ ENTREZ ]
RefSeq	NM_130436 [ SRS ]    NM_130436 [ ENTREZ ]
RefSeq	NM_130437 [ SRS ]    NM_130437 [ ENTREZ ]
RefSeq	NM_130438 [ SRS ]    NM_130438 [ ENTREZ ]
RefSeq	AC_000064 [ SRS ]    AC_000064 [ ENTREZ ]
RefSeq	AC_000153 [ SRS ]    AC_000153 [ ENTREZ ]
RefSeq	NC_000021 [ SRS ]    NC_000021 [ ENTREZ ]
RefSeq	NT_011512 [ SRS ]    NT_011512 [ ENTREZ ]
RefSeq	NW_001838706 [ SRS ]    NW_001838706 [ ENTREZ ]
RefSeq	NW_927384 [ SRS ]    NW_927384 [ ENTREZ ]
AceView	DYRK1A AceView - NCBI
Unigene	Hs.368240 [ SRS ]    Hs.368240 [ NCBI ]     HS368240 [ spliceNest ]
Fast-db	2758 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O60770 [ SRS]    O60770 [ EXPASY ]     O60770 [ INTERPRO ]     O60770 [ UNIPROT ]
CluSTr	O60770
Blocks	O60770
HPRD	09018
	Protein Interaction databases
DIP	O60770
IntAct	O60770
	Polymorphism : SNP, mutations, diseases
OMIM	600855    [ map ]
GENECLINICS	600855
SNP	DYRK1A [dbSNP-NCBI]
SNP	NM_001396 [SNP-NCI]
SNP	NM_101395 [SNP-NCI]
SNP	NM_130436 [SNP-NCI]
SNP	NM_130437 [SNP-NCI]
SNP	NM_130438 [SNP-NCI]
SNP	DYRK1A [GeneSNPs - Utah]  DYRK1A] [HGBASE - SRS]
HAPMAP	DYRK1A [HAPMAP]
COSMIC	DYRK1A [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DYRK1A
	General knowledge
Family Browser	DYRK1A [UCSC Family Browser]
SOURCE	NM_001396
SOURCE	NM_101395
SOURCE	NM_130436
SOURCE	NM_130437
SOURCE	NM_130438
SMD	Hs.368240
SAGE	Hs.368240
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	non-membrane spanning protein tyrosine kinase activity [Amigo]  non-membrane spanning protein tyrosine kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	nervous system development [Amigo]  nervous system development
GO	kinase activity [Amigo]  kinase activity
GO	nuclear speck [Amigo]  nuclear speck
GO	transferase activity [Amigo]  transferase activity
GO	peptidyl-tyrosine phosphorylation [Amigo]  peptidyl-tyrosine phosphorylation
GO	protein self-association [Amigo]  protein self-association
GO	protein amino acid autophosphorylation [Amigo]  protein amino acid autophosphorylation
BIOCARTA	Sonic Hedgehog (Shh) Pathway    [Genes]
PubGene	DYRK1A
TreeFam	DYRK1A
CTD	1859 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DYRK1A Related clones (RZPD - Berlin)
	PubMed
PubMed	47 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:39:17 2008