DYRK4 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4)

Identity

Other names	-
HGNC	DYRK4
Location	12p13.32
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DYRK4   3095
Entrez_Gene	DYRK4  8798  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
	Cards
GeneCards	DYRK4
Ensembl	DYRK4 [Search_View]   ENSG00000010219 [Gene_View]
Genatlas	DYRK4
GeneLynx	DYRK4
eGenome	DYRK4
euGene	8798
	Genomic and cartography
GoldenPath	DYRK4  -  12p13.32   chr12:4569505-4593302 +  12p13.32   [Description]    (hg18-March_2006)
Ensembl	DYRK4 - 12p13.32 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DYRK4
	Gene and transcription
Genbank	AF263541 [ ENTREZ ]
Genbank	AK292322 [ ENTREZ ]
Genbank	AK308260 [ ENTREZ ]
Genbank	AK308702 [ ENTREZ ]
Genbank	BC031244 [ ENTREZ ]
RefSeq	NM_003845 [ SRS ]    NM_003845 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NT_009759 [ SRS ]    NT_009759 [ ENTREZ ]
RefSeq	NW_001838049 [ SRS ]    NW_001838049 [ ENTREZ ]
RefSeq	NW_925295 [ SRS ]    NW_925295 [ ENTREZ ]
AceView	DYRK4 AceView - NCBI
Unigene	Hs.439530 [ SRS ]    Hs.439530 [ NCBI ]     HS439530 [ spliceNest ]
Fast-db	762 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9NR20 [ SRS]    Q9NR20 [ EXPASY ]     Q9NR20 [ INTERPRO ]     Q9NR20 [ UNIPROT ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q9NR20
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q9NR20 DYRK4_HUMAN [ Domain structure ]   Q9NR20 DYRK4_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q9NR20
HPRD	10926
	Protein Interaction databases
DIP	Q9NR20
IntAct	Q9NR20
	Polymorphism : SNP, mutations, diseases
OMIM	609181    [ map ]
GENECLINICS	609181
SNP	DYRK4 [dbSNP-NCBI]
SNP	NM_003845 [SNP-NCI]
SNP	DYRK4 [GeneSNPs - Utah]  DYRK4] [HGBASE - SRS]
HAPMAP	DYRK4 [HAPMAP]
COSMIC	DYRK4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DYRK4
	General knowledge
Family Browser	DYRK4 [UCSC Family Browser]
SOURCE	NM_003845
SMD	Hs.439530
SAGE	Hs.439530
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein tyrosine kinase activity [Amigo]  protein tyrosine kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	cellular_component [Amigo]  cellular_component
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	transferase activity [Amigo]  transferase activity
KEGG	Inositol phosphate metabolism
KEGG	Benzoate degradation via CoA ligation
KEGG	Nicotinate and nicotinamide metabolism
KEGG	Phosphatidylinositol signaling system
PubGene	DYRK4
TreeFam	DYRK4
CTD	8798 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DYRK4 Related clones (RZPD - Berlin)
	PubMed
PubMed	6 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:08:55 2008