E2F1 (E2F transcription factor 1)

Identity

Other names	E2F-1
	RBAP1
	RBBP3
	RBP3
HGNC	E2F1
Location	20q11
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	E2F1   3113
Entrez_Gene	E2F1  1869  E2F transcription factor 1
	Cards
GeneCards	E2F1
Ensembl	E2F1 [Search_View]   ENSG00000101412 [Gene_View]
Genatlas	E2F1
GeneLynx	E2F1
eGenome	E2F1
euGene	1869
	Genomic and cartography
GoldenPath	E2F1  -  20q11   chr20:31726953-31737871 -  20q11.22   [Description]    (hg18-March_2006)
Ensembl	E2F1 - 20q11.22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	E2F1
	Gene and transcription
Genbank	AF086380 [ ENTREZ ]
Genbank	BC005098 [ ENTREZ ]
Genbank	BC050369 [ ENTREZ ]
Genbank	BC058902 [ ENTREZ ]
Genbank	CR593152 [ ENTREZ ]
RefSeq	NM_005225 [ SRS ]    NM_005225 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_028392 [ SRS ]    NT_028392 [ ENTREZ ]
RefSeq	NW_001838664 [ SRS ]    NW_001838664 [ ENTREZ ]
RefSeq	NW_927339 [ SRS ]    NW_927339 [ ENTREZ ]
AceView	E2F1 AceView - NCBI
Unigene	Hs.654393 [ SRS ]    Hs.654393 [ NCBI ]     HS654393 [ spliceNest ]
Fast-db	8421 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q01094 [ SRS]    Q01094 [ EXPASY ]     Q01094 [ INTERPRO ]     Q01094 [ UNIPROT ]
Interpro	IPR015633 E2F [ SRS ]    IPR015633 E2F [ EBI ]
Interpro	IPR015634 E2F1 [ SRS ]    IPR015634 E2F1 [ EBI ]
Interpro	IPR003316 E2F_TDP [ SRS ]    IPR003316 E2F_TDP [ EBI ]
Interpro	IPR011991 Wing_hlx_DNA_bd [ SRS ]    IPR011991 Wing_hlx_DNA_bd [ EBI ]
CluSTr	Q01094
Pfam	PF02319 E2F_TDP [ SRS ]    PF02319 E2F_TDP [ Sanger ]    pfam02319 [ NCBI-CDD ]
Blocks	Q01094
PDB	1H24 [ SRS ]    1H24 [ PdbSum ],   1H24 [ IMB ]   1H24 [ RSDB ]
PDB	1O9K [ SRS ]    1O9K [ PdbSum ],   1O9K [ IMB ]   1O9K [ RSDB ]
PDB	2AZE [ SRS ]    2AZE [ PdbSum ],   2AZE [ IMB ]   2AZE [ RSDB ]
HPRD	01806
	Protein Interaction databases
DIP	Q01094
IntAct	Q01094
	Polymorphism : SNP, mutations, diseases
OMIM	189971    [ map ]
GENECLINICS	189971
SNP	E2F1 [dbSNP-NCBI]
SNP	NM_005225 [SNP-NCI]
SNP	E2F1 [GeneSNPs - Utah]  E2F1] [HGBASE - SRS]
HAPMAP	E2F1 [HAPMAP]
COSMIC	E2F1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	E2F1
	General knowledge
Family Browser	E2F1 [UCSC Family Browser]
SOURCE	NM_005225
SMD	Hs.654393
SAGE	Hs.654393
GO	G1 phase of mitotic cell cycle [Amigo]  G1 phase of mitotic cell cycle
GO	negative regulation of transcription from RNA polymerase II promoter [Amigo]  negative regulation of transcription from RNA polymerase II promoter
GO	transcription factor activity [Amigo]  transcription factor activity
GO	transcription factor activity [Amigo]  transcription factor activity
GO	transcription corepressor activity [Amigo]  transcription corepressor activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	transcription factor complex [Amigo]  transcription factor complex
GO	cytoplasm [Amigo]  cytoplasm
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	apoptosis [Amigo]  apoptosis
GO	cell cycle [Amigo]  cell cycle
GO	cell proliferation [Amigo]  cell proliferation
GO	transcription activator activity [Amigo]  transcription activator activity
GO	forebrain development [Amigo]  forebrain development
GO	positive regulation of transcription from RNA polymerase II promoter [Amigo]  positive regulation of transcription from RNA polymerase II promoter
PubGene	E2F1
TreeFam	E2F1
CTD	1869 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	E2F1 Related clones (RZPD - Berlin)
	PubMed
PubMed	241 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:08:56 2008