EEF2K (eukaryotic elongation factor-2 kinase)

Identity

Other names	HSU93850
	MGC45041
	eEF-2K
HGNC	EEF2K
Location	16p12
Location_base_pair	Starts at 22125093 and ends at 22207567 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	EEF2K   24615
Entrez_Gene	EEF2K  29904  eukaryotic elongation factor-2 kinase
	Cards
GeneCards	EEF2K
Ensembl	EEF2K [Search_View]   ENSG00000103319 [Gene_View]
Genatlas	EEF2K
GeneLynx	EEF2K
eGenome	EEF2K
euGene	29904
	Genomic and cartography
GoldenPath	EEF2K  -  16p12   chr16:22125093-22207567 +  16p12.1   [Description]    (hg18-March_2006)
Ensembl	EEF2K - 16p12.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	EEF2K
	Gene and transcription
Genbank	AK022569 [ ENTREZ ]
Genbank	AK308757 [ ENTREZ ]
Genbank	AW675420 [ ENTREZ ]
Genbank	BC032665 [ ENTREZ ]
Genbank	CA397138 [ ENTREZ ]
RefSeq	NM_013302 [ SRS ]    NM_013302 [ ENTREZ ]
RefSeq	AC_000059 [ SRS ]    AC_000059 [ ENTREZ ]
RefSeq	AC_000148 [ SRS ]    AC_000148 [ ENTREZ ]
RefSeq	NC_000016 [ SRS ]    NC_000016 [ ENTREZ ]
RefSeq	NT_010393 [ SRS ]    NT_010393 [ ENTREZ ]
RefSeq	NW_001838389 [ SRS ]    NW_001838389 [ ENTREZ ]
RefSeq	NW_926195 [ SRS ]    NW_926195 [ ENTREZ ]
AceView	EEF2K AceView - NCBI
Unigene	Hs.713571 [ SRS ]    Hs.713571 [ NCBI ]     HS713571 [ spliceNest ]
Fast-db	5277 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O00418 [ SRS]    O00418 [ EXPASY ]     O00418 [ INTERPRO ]     O00418 [ UNIPROT ]
Prosite	PS51158 ALPHA_KINASE [ SRS ]    PS51158 ALPHA_KINASE [ Expasy ]
Interpro	IPR017400 Elongation_factor_2_kinase [ SRS ]    IPR017400 Elongation_factor_2_kinase [ EBI ]
Interpro	IPR004166 MHCK_EF2_kinase [ SRS ]    IPR004166 MHCK_EF2_kinase [ EBI ]
Interpro	IPR006597 Sel1_like [ SRS ]    IPR006597 Sel1_like [ EBI ]
Interpro	IPR011990 TPR-like_helical [ SRS ]    IPR011990 TPR-like_helical [ EBI ]
CluSTr	O00418
Pfam	PF02816 Alpha_kinase [ SRS ]    PF02816 Alpha_kinase [ Sanger ]    pfam02816 [ NCBI-CDD ]
Pfam	PF08238 Sel1 [ SRS ]    PF08238 Sel1 [ Sanger ]    pfam08238 [ NCBI-CDD ]
Smart	SM00811 Alpha_kinase [EMBL]
Blocks	O00418
HPRD	07369
	Protein Interaction databases
DIP	O00418
IntAct	O00418
	Polymorphism : SNP, mutations, diseases
OMIM	606968    [ map ]
GENECLINICS	606968
SNP	EEF2K [dbSNP-NCBI]
SNP	NM_013302 [SNP-NCI]
SNP	EEF2K [GeneSNPs - Utah]  EEF2K] [HGBASE - SRS]
HAPMAP	EEF2K [HAPMAP]
COSMIC	EEF2K [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	EEF2K
	General knowledge
Family Browser	EEF2K [UCSC Family Browser]
SOURCE	NM_013302
SMD	Hs.713571
SAGE	Hs.713571
Enzyme	2.7.11.20 [ Enzyme-Expasy ]   2.7.11.20 [ Enzyme-SRS ]   2.7.11.20 [ IntEnz-EBI ]   2.7.11.20 [ BRENDA ]   2.7.11.20 [ KEGG ]   2.7.11.20 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	elongation factor-2 kinase activity [Amigo]  elongation factor-2 kinase activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	calmodulin binding [Amigo]  calmodulin binding
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	translational elongation [Amigo]  translational elongation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	translation factor activity, nucleic acid binding [Amigo]  translation factor activity, nucleic acid binding
GO	transferase activity [Amigo]  transferase activity
BIOCARTA	Eukaryotic protein translation    [Genes]
PubGene	EEF2K
TreeFam	EEF2K
CTD	29904 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	EEF2K Related clones (RZPD - Berlin)
	PubMed
PubMed	22 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:39:30 2008