EIF5A (eukaryotic translation initiation factor 5A)

Identity

Other names	A
	EIF-5A
	EIF5A1
	MGC104255
	MGC99547
	uORF
	uORF A
HGNC	EIF5A
Location	17p13-p12
Location_base_pair	Starts at 7151693 and ends at 7156498 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	EIF5A   3300
Entrez_Gene	EIF5A  1984  eukaryotic translation initiation factor 5A
	Cards
GeneCards	EIF5A
Ensembl	EIF5A [Search_View]   ENSG00000132507 [Gene_View]
Genatlas	EIF5A
GeneLynx	EIF5A
eGenome	EIF5A
euGene	1984
	Genomic and cartography
GoldenPath	EIF5A  -     chr17:7151693-7156498 +  17p13.1   [Description]    (hg18-March_2006)
Ensembl	EIF5A - 17p13.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	EIF5A
	Gene and transcription
Genbank	AF087992 [ ENTREZ ]
Genbank	AF376057 [ ENTREZ ]
Genbank	AK222585 [ ENTREZ ]
Genbank	AK292615 [ ENTREZ ]
Genbank	AY129319 [ ENTREZ ]
RefSeq	NM_001970 [ SRS ]    NM_001970 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	EIF5A AceView - NCBI
Unigene	Hs.534314 [ SRS ]    Hs.534314 [ NCBI ]     HS534314 [ spliceNest ]
Fast-db	2860 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P63241 [ SRS]    P63241 [ EXPASY ]     P63241 [ INTERPRO ]     P63241 [ UNIPROT ]
Prosite	PS00302 IF5A_HYPUSINE [ SRS ]    PS00302 IF5A_HYPUSINE [ Expasy ]
Interpro	IPR001884 EIF5A_hypusine [ SRS ]    IPR001884 EIF5A_hypusine [ EBI ]
Interpro	IPR012340 NA-bd_OB-fold [ SRS ]    IPR012340 NA-bd_OB-fold [ EBI ]
Interpro	IPR014722 Transl_SH3_like_sub [ SRS ]    IPR014722 Transl_SH3_like_sub [ EBI ]
CluSTr	P63241
Pfam	PF01287 eIF-5a [ SRS ]    PF01287 eIF-5a [ Sanger ]    pfam01287 [ NCBI-CDD ]
Blocks	P63241
PDB	1FH4 [ SRS ]    1FH4 [ PdbSum ],   1FH4 [ IMB ]   1FH4 [ RSDB ]
PDB	3CPF [ SRS ]    3CPF [ PdbSum ],   3CPF [ IMB ]   3CPF [ RSDB ]
HPRD	02555
	Protein Interaction databases
DIP	P63241
IntAct	P63241
	Polymorphism : SNP, mutations, diseases
OMIM	600187    [ map ]
GENECLINICS	600187
SNP	EIF5A [dbSNP-NCBI]
SNP	NM_001970 [SNP-NCI]
SNP	EIF5A [GeneSNPs - Utah]  EIF5A] [HGBASE - SRS]
HAPMAP	EIF5A [HAPMAP]
HGMD	EIF5A
	General knowledge
Family Browser	EIF5A [UCSC Family Browser]
SOURCE	NM_001970
SMD	Hs.534314
SAGE	Hs.534314
GO	RNA binding [Amigo]  RNA binding
GO	translation initiation factor activity [Amigo]  translation initiation factor activity
GO	nucleus [Amigo]  nucleus
GO	annulate lamellae [Amigo]  annulate lamellae
GO	nuclear pore [Amigo]  nuclear pore
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	mRNA export from nucleus [Amigo]  mRNA export from nucleus
GO	protein export from nucleus [Amigo]  protein export from nucleus
GO	nucleocytoplasmic transport [Amigo]  nucleocytoplasmic transport
GO	nucleocytoplasmic transport [Amigo]  nucleocytoplasmic transport
GO	apoptosis [Amigo]  apoptosis
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	cell proliferation [Amigo]  cell proliferation
GO	peptidyl-lysine modification to hypusine [Amigo]  peptidyl-lysine modification to hypusine
GO	U6 snRNA binding [Amigo]  U6 snRNA binding
GO	viral genome replication [Amigo]  viral genome replication
GO	positive regulation of translational initiation [Amigo]  positive regulation of translational initiation
GO	protein N-terminus binding [Amigo]  protein N-terminus binding
PubGene	EIF5A
TreeFam	EIF5A
CTD	1984 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	EIF5A Related clones (RZPD - Berlin)
	PubMed
PubMed	51 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:39:45 2008