FAS (Fas (TNF receptor superfamily, member 6))

Identity

Other names	ALPS1A
	APO-1
	APT1
	CD95
	FAS1
	FASTM
	TNFRSF6
HGNC	FAS
Location	10q24.1
Location_base_pair	Starts at 90740268 and ends at 90765522 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	FAS   11920
Entrez_Gene	FAS  355  Fas (TNF receptor superfamily, member 6)
	Cards
GeneCards	FAS
Ensembl	FAS [Search_View]   ENSG00000026103 [Gene_View]
Genatlas	FAS
GeneLynx	FAS
eGenome	FAS
euGene	355
	Genomic and cartography
GoldenPath	FAS  -  10q24.1   chr10:90740268-90765522 +  10q23.31   [Description]    (hg18-March_2006)
Ensembl	FAS - 10q23.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	FAS
	Gene and transcription
Genbank	AB209361 [ ENTREZ ]
Genbank	AK290978 [ ENTREZ ]
Genbank	AK311164 [ ENTREZ ]
Genbank	AK311424 [ ENTREZ ]
Genbank	AK311499 [ ENTREZ ]
RefSeq	NM_000043 [ SRS ]    NM_000043 [ ENTREZ ]
RefSeq	NM_152871 [ SRS ]    NM_152871 [ ENTREZ ]
RefSeq	NM_152872 [ SRS ]    NM_152872 [ ENTREZ ]
RefSeq	NM_152873 [ SRS ]    NM_152873 [ ENTREZ ]
RefSeq	NM_152874 [ SRS ]    NM_152874 [ ENTREZ ]
RefSeq	NM_152875 [ SRS ]    NM_152875 [ ENTREZ ]
RefSeq	NM_152876 [ SRS ]    NM_152876 [ ENTREZ ]
RefSeq	NM_152877 [ SRS ]    NM_152877 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_030059 [ SRS ]    NT_030059 [ ENTREZ ]
RefSeq	NW_001838005 [ SRS ]    NW_001838005 [ ENTREZ ]
RefSeq	NW_924884 [ SRS ]    NW_924884 [ ENTREZ ]
AceView	FAS AceView - NCBI
Unigene	Hs.244139 [ SRS ]    Hs.244139 [ NCBI ]     HS244139 [ spliceNest ]
Fast-db	15295 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P25445 [ SRS]    P25445 [ EXPASY ]     P25445 [ INTERPRO ]     P25445 [ UNIPROT ]
Prosite	PS50017 DEATH_DOMAIN [ SRS ]    PS50017 DEATH_DOMAIN [ Expasy ]
Prosite	PS00652 TNFR_NGFR_1 [ SRS ]    PS00652 TNFR_NGFR_1 [ Expasy ]
Prosite	PS50050 TNFR_NGFR_2 [ SRS ]    PS50050 TNFR_NGFR_2 [ Expasy ]
Interpro	IPR000488 Death [ SRS ]    IPR000488 Death [ EBI ]
Interpro	IPR011029 DEATH_like [ SRS ]    IPR011029 DEATH_like [ EBI ]
Interpro	IPR008063 Fas_rcpt [ SRS ]    IPR008063 Fas_rcpt [ EBI ]
Interpro	IPR001368 TNFR_c6 [ SRS ]    IPR001368 TNFR_c6 [ EBI ]
CluSTr	P25445
Pfam	PF00531 Death [ SRS ]    PF00531 Death [ Sanger ]    pfam00531 [ NCBI-CDD ]
Pfam	PF00020 TNFR_c6 [ SRS ]    PF00020 TNFR_c6 [ Sanger ]    pfam00020 [ NCBI-CDD ]
Smart	SM00005 DEATH [EMBL]
Smart	SM00208 TNFR [EMBL]
Blocks	P25445
PDB	1BZI [ SRS ]    1BZI [ PdbSum ],   1BZI [ IMB ]   1BZI [ RSDB ]
PDB	1DDF [ SRS ]    1DDF [ PdbSum ],   1DDF [ IMB ]   1DDF [ RSDB ]
HPRD	00609
	Protein Interaction databases
DIP	P25445
IntAct	P25445
	Polymorphism : SNP, mutations, diseases
OMIM	134637;601859    [ map ]
GENECLINICS	134637;601859
SNP	FAS [dbSNP-NCBI]
SNP	NM_000043 [SNP-NCI]
SNP	NM_152871 [SNP-NCI]
SNP	NM_152872 [SNP-NCI]
SNP	NM_152873 [SNP-NCI]
SNP	NM_152874 [SNP-NCI]
SNP	NM_152875 [SNP-NCI]
SNP	NM_152876 [SNP-NCI]
SNP	NM_152877 [SNP-NCI]
SNP	FAS [GeneSNPs - Utah]  FAS] [HGBASE - SRS]
HAPMAP	FAS [HAPMAP]
COSMIC	FAS [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	FAS
	General knowledge
Family Browser	FAS [UCSC Family Browser]
SOURCE	NM_000043
SOURCE	NM_152871
SOURCE	NM_152872
SOURCE	NM_152873
SOURCE	NM_152874
SOURCE	NM_152875
SOURCE	NM_152876
SOURCE	NM_152877
SMD	Hs.244139
SAGE	Hs.244139
GO	transmembrane receptor activity [Amigo]  transmembrane receptor activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	soluble fraction [Amigo]  soluble fraction
GO	cytosol [Amigo]  cytosol
GO	plasma membrane [Amigo]  plasma membrane
GO	plasma membrane [Amigo]  plasma membrane
GO	protein complex assembly [Amigo]  protein complex assembly
GO	apoptosis [Amigo]  apoptosis
GO	anti-apoptosis [Amigo]  anti-apoptosis
GO	immune response [Amigo]  immune response
GO	signal transduction [Amigo]  signal transduction
GO	signal transduction [Amigo]  signal transduction
GO	induction of apoptosis by extracellular signals [Amigo]  induction of apoptosis by extracellular signals
GO	activation of pro-apoptotic gene products [Amigo]  activation of pro-apoptotic gene products
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	identical protein binding [Amigo]  identical protein binding
GO	regulation of apoptosis [Amigo]  regulation of apoptosis
BIOCARTA	HIV-I Nef: negative effector of Fas and TNF    [Genes]
BIOCARTA	Antigen Dependent B Cell Activation    [Genes]
BIOCARTA	Bystander B Cell Activation    [Genes]
BIOCARTA	CTL mediated immune response against target cells    [Genes]
BIOCARTA	FAS signaling pathway ( CD95 )    [Genes]
BIOCARTA	Stress Induction of HSP Regulation    [Genes]
BIOCARTA	IL-2 Receptor Beta Chain in T cell Activation    [Genes]
BIOCARTA	Keratinocyte Differentiation    [Genes]
BIOCARTA	Regulation of transcriptional activity by PML    [Genes]
BIOCARTA	HIV Induced T Cell Apoptosis    [Genes]
KEGG	MAPK signaling pathway
KEGG	Cytokine-cytokine receptor interaction
KEGG	Apoptosis
KEGG	Natural killer cell mediated cytotoxicity
KEGG	Type I diabetes mellitus
PubGene	FAS
TreeFam	FAS
CTD	355 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	FAS Related clones (RZPD - Berlin)
	PubMed
PubMed	499 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:40:56 2008